There are 4 ways to get from Santa Cruz to Santiago by plane, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Viru Viru International Airport (VVI) to Comodoro Arturo Merino Benítez International Airport (SCL)plane VVI - SCL
5h 59m$172–554Bus
cheapest- Take the bus from Santa Cruz to Terminal Alameda - Turbusbus Santa Cruz
40h 11m$48Bus via Mendoza
- Take the bus from Santa Cruz to Terminal Mendozabus
- Take the bus from Terminal Mendoza to Terminal Sur de Santiagobus Santiago
38h 4m$118–193Drive 2,429.6 km
- Drive from Santa Cruz de la Sierra to Santiagocar 2,429.6 km
31h 26m$300–433
Viru Viru International Airport (VVI) to Comodoro Arturo Merino Benítez International Airport (SCL) flights
Questions & Answers
The cheapest way to get from Santa Cruz to Santiago is to bus which costs $47 - $48 and takes 40h 11m.
The fastest way to get from Santa Cruz to Santiago is to fly which takes 5h 59m and costs $170 - $600.
No, there is no direct bus from Santa Cruz to Santiago. However, there are services departing from Santa Cruz and arriving at Terminal Sur de Santiago via Terminal Mendoza. The journey, including transfers, takes approximately 38h 4m.
The distance between Santa Cruz and Santiago is 1941 km. The road distance is 2429.6 km.
The best way to get from Santa Cruz to Santiago without a car is to bus via Mendoza which takes 38h 4m and costs $110 - $200.
It takes approximately 5h 59m to get from Santa Cruz to Santiago, including transfers.
Santa Cruz to Santiago bus services, operated by Autobuses Quirquincho, depart from Santa Cruz station.
The best way to get from Santa Cruz to Santiago is to fly which takes 5h 59m and costs $170 - $600. Alternatively, you can bus via Mendoza, which costs $110 - $200 and takes 38h 4m.
Santa Cruz to Santiago bus services, operated by Autobuses Quirquincho, arrive at Terminal Mendoza station.
Yes, the driving distance between Santa Cruz to Santiago is 2430 km. It takes approximately 31h 26m to drive from Santa Cruz to Santiago.
What companies run services between Santa Cruz, Bolivia and Santiago, Chile?
Boliviana de Aviación and LATAM Chile fly from Viru Viru International Airport (VVI) to Comodoro Arturo Merino Benítez International Airport (SCL) 5 times a week. Alternatively, you can take a vehicle from Santa Cruz de la Sierra to Terminal Sur de Santiago via Santa Cruz and Terminal Mendoza in around 38h 4m.
- Website
- latam.com
Flights from Viru Viru International Airport to Comodoro Arturo Merino Benítez International Airport
- Ave. Duration
- 3h 9m
- When
- Wednesday, Thursday, and Saturday
- Estimated price
- $220–550
- Website
- boa.bo
Flights from Viru Viru International Airport to Comodoro Arturo Merino Benítez International Airport
- Ave. Duration
- 3h 15m
- When
- Tuesday and Friday
- Estimated price
- $160–470
- Phone
- +59171291772
- Website
- grupoempresarialquirquincho.com
Bus from Santa Cruz to Terminal Mendoza
- Ave. Duration
- 31h
- Frequency
- Twice a week
- Estimated price
- $100–150
- Schedules at
- grupoempresarialquirquincho.com
- Phone
- +56 9 5950 0854
- [email protected]
- Website
- chiarinternacional.cl
Bus from Terminal Mendoza to Terminal Sur de Santiago
- Ave. Duration
- 6h
- Frequency
- Twice daily
- Estimated price
- $38
- Schedules at
- chiarinternacional.cl
- Phone
- 0800 122 2282
- [email protected]
- Website
- catainternacional.com
Bus from Terminal Mendoza to Terminal Sur de Santiago
- Ave. Duration
- 9h
- Frequency
- Twice daily
- Estimated price
- $18–44
- Website
- https://www.catainternacional.com/en
- Ejecutivo
- $23–35
- Semi Cama
- $18–26
- Ejecutivo Individual
- $26–35
- Phone
- 0810 122 1122
- [email protected]
- Website
- andesmar.com
Bus from Terminal Mendoza to Terminal Sur de Santiago
- Ave. Duration
- 9h
- Frequency
- Twice daily
- Estimated price
- $15–41
- Schedules at
- andesmar.com
- Book at
- andesmar.com
- Bed
- $18–26
- Semi bed
- $15–21
- Phone
- +56 9 7242 8977
- [email protected]
- Website
- mathostour.cl
Bus from Terminal Mendoza to Terminal Sur de Santiago
- Ave. Duration
- 8h 30m
- Frequency
- Once daily
- Estimated price
- $38
- Schedules at
- mathostour.cl
- Book at
- kupos.cl
- Phone
- 0810 122 1122
- [email protected]
- Website
- andesmar.com
Bus from Terminal Mendoza to Terminal Sur de Santiago
- Ave. Duration
- 7h
- Frequency
- Twice a week
- Estimated price
- $34
- Schedules at
- andesmar.com
- Phone
- +591 2527 7355
- [email protected]
- Website
- facebook.com
Bus from Santa Cruz to Terminal Alameda - Turbus
- Ave. Duration
- 40h
- Frequency
- 4 times a week
- Estimated price
- $44
- Schedules at
- facebook.com
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