There are 4 ways to get from Santa Cruz to Uyuni by plane, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Viru Viru International Airport (VVI) to Uyuni Airport (UYU)plane VVI - UYU
4h 27m$217–429Bus
cheapest- Take the bus from Santa Cruz to Sucrebus Santa Cruz de la Sierra
- Take the bus from Sucre to Uyunibus Uyuni
20h 4m$27–59Bus via Samaipata
- Take the bus from Santa Cruz to Samaipatabus
- Take the bus from Samaipata to Sucrebus
- Take the bus from Sucre to Uyunibus
18h 40m$59–88Drive 813.4 km
- Drive from Santa Cruz de la Sierra to Uyunicar 813.4 km
12h 29m$40–58
Viru Viru International Airport (VVI) to Uyuni Airport (UYU) flights
Questions & Answers
The cheapest way to get from Santa Cruz to Uyuni is to drive which costs $35 - $60 and takes 12h 29m.
The fastest way to get from Santa Cruz to Uyuni is to fly which takes 4h 27m and costs $210 - $430.
No, there is no direct bus from Santa Cruz to Uyuni. However, there are services departing from Santa Cruz and arriving at Uyuni via Samaipata and Sucre. The journey, including transfers, takes approximately 18h 40m.
The distance between Santa Cruz and Uyuni is 520 km. The road distance is 813.4 km.
The best way to get from Santa Cruz to Uyuni without a car is to bus via Samaipata which takes 18h 40m and costs $55 - $90.
It takes approximately 4h 27m to get from Santa Cruz to Uyuni, including transfers.
Santa Cruz to Uyuni bus services, operated by Trufi Expreso Samaipata, depart from Santa Cruz station.
The best way to get from Santa Cruz to Uyuni is to fly which takes 4h 27m and costs $210 - $430. Alternatively, you can bus via Samaipata, which costs $55 - $90 and takes 18h 40m.
Santa Cruz to Uyuni bus services, operated by Trufi Expreso Samaipata, arrive at Samaipata station.
Yes, the driving distance between Santa Cruz to Uyuni is 813 km. It takes approximately 12h 29m to drive from Santa Cruz to Uyuni.
What companies run services between Santa Cruz, Bolivia and Uyuni, Potosí, Bolivia?
Boliviana de Aviación and Eco Jet fly from Viru Viru International Airport (VVI) to Uyuni Airport (UYU) 4 times a day. Alternatively, you can take a bus from Santa Cruz to Uyuni via Samaipata and Sucre in around 18h 40m.
- Website
- boa.bo
Flights from Viru Viru International Airport to Uyuni Airport via La Paz
- Ave. Duration
- 3h 36m
- When
- Every day
- Estimated price
- $110–650
Flights from Viru Viru International Airport to Uyuni Airport via Cochabamba, La Paz
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $210–410
- Phone
- +591 71355988
- Website
- facebook.com
Bus from Santa Cruz to Samaipata
- Ave. Duration
- 2h 40m
- Frequency
- Hourly
- Estimated price
- $4
- Schedules at
- facebook.com
- Phone
- +591 7116 2591
- Website
- busbud.com
Bus from Samaipata to Sucre
- Ave. Duration
- 8h
- Frequency
- Once daily
- Estimated price
- $26–40
- Book at
- ticketsbolivia.com.bo
Bus from Sucre to Uyuni
- Ave. Duration
- 8h
- Frequency
- Once daily
- Estimated price
- $30–45
- Book at
- ticketsbolivia.com.bo
- Phone
- +591 71162386
- Website
- facebook.com
Bus from Sucre to Uyuni
- Ave. Duration
- 6h
- Frequency
- Once daily
- Estimated price
- $6
- Schedules at
- facebook.com
- Rioad
- $6
- Phone
- +591-72233555
- [email protected]
- Website
- transcopacabanasa.com
Bus from Santa Cruz to Sucre
- Ave. Duration
- 11h
- Frequency
- Once daily
- Estimated price
- $10–16
- Schedules at
- transcopacabanasa.com
- Phone
- +591 72323251
- Website
- facebook.com
Bus from Sucre to Uyuni
- Ave. Duration
- 8h
- Frequency
- Once daily
- Estimated price
- $14–40
- Book at
- busbud.com
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