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How to get fromSanta Cruz to Des Moinesby taxi, plane, bus (Amtrak, Greyhound, Flixbus), bus, train, or car

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There are 9 ways to get from Santa Cruz to Des Moines by taxi, plane, bus (Amtrak, Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Monterey Regional Airport, fly

    best
    1. Take the taxi from Santa Cruz to Monterey Regional Airport (MRY)taxi taxi
    2. Fly from Monterey Regional Airport (MRY) to Des Moines (DSM)plane plane MRY - DSM
    6h 33m
    $371–1,091

  2. Bus, Caltrain to San Francisco International Airport, fly

    cheapest
    1. Take the bus from Front to Diridon Stationbus bus
    2. Take the train from San Jose Diridon Caltrain Northbound to Millbrae Caltrain Northboundtrain train
    3. Fly from San Francisco International Airport (SFO) to Des Moines (DSM)plane plane SFO - DSM
    8h 42m
    $232–706

  3. Bus

    1. Take the bus from Front to Diridon Stationbus bus 17
    2. Take the bus from San Jose Diridon Station to Oaklandbus bus
    3. Take the bus from Oakland to Sparks Transit Centerbus bus
    4. Take the bus from Sparks Transit Center to Denver Union Stationbus bus
    5. Take the bus from Denver Union Station to Des Moinesbus bus
    45h 14m
    $296–592

  4. Bus, train

    1. Take the bus from Front to Diridon Stationbus bus 17
    2. Take the train from San Jose to Emeryvilletrain train
    3. Take the train from Emeryville to Denvertrain train
    4. Take the bus from Denver Union Station to Des Moinesbus bus
    2d 3h
    $555–1,149

  5. Drive 1,853.9 mi

    1. Drive from Santa Cruz to Des Moinescar car 1,853.9 mi
    28h 26m
    $339–489

  6. Bus to Norman Y. Mineta San José International Airport, fly

    1. Take the bus from Front to Diridon Stationbus bus
    2. Fly from Norman Y. Mineta San José International Airport (SJC) to Des Moines (DSM)plane plane SJC - DSM
    8h 9m
    $233–944

  7. Bus, train to Oakland International Airport, fly

    1. Take the bus from Front to Diridon Stationbus bus
    2. Take the train from San Jose to Oakland Coliseum/Airport Amtraktrain train
    3. Fly from Oakland International Airport (OAK) to Des Moines (DSM)plane plane OAK - DSM
    9h 20m
    $251–1,014

  8. Bus, train via Omaha

    1. Take the bus from Ocean & Water to Diridon Stationbus bus 17
    2. Take the bus from San Jose to Emeryvillebus bus
    3. Take the train from Emeryville to Denvertrain train
    4. Take the bus from Denver to Omaha, NEbus bus
    5. Take the bus from Omaha, NE to Des Moinesbus bus
    2d 4h
    $621–1,154

  9. Bus, train #2

    1. Take the bus from Front to Diridon Stationbus bus 17
    2. Take the train from San Jose to Los Angelestrain train
    3. Take the train from Los Angeles to Kansas Citytrain train
    4. Take the bus from Kansas City Bus Station to Des Moinesbus bus
    2d 5h
    $719–1,554

Santa Cruz to Des Moines by bus

Calendar14Weekly Buses
Duration45h 14mAverage Duration
Ticket$296Cheapest Price
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Questions & Answers

Map of how to get from Santa Cruz to Des Moines.ExpandLaunch map view
  • Distance: 1,592.6 mi
  • Duration: 6h 33m

What companies run services between Santa Cruz, CA, USA and Des Moines, IA, USA?

You can take a bus from Front to Des Moines via Diridon Station, San Jose Diridon Station, Oakland, Sparks Transit Center, and Denver Union Station in around 45h 14m.

Airlines
Train operators
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