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How to get fromSanta Cruz to Hesperiaby bus (Amtrak, Greyhound, Flixbus), bus, train, car, plane, or bus (Amtrak)

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There are 11 ways to get from Santa Cruz to Hesperia by bus (Amtrak, Greyhound, Flixbus), bus, train, car, plane, or bus (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus via Los Angeles

    best
    1. Take the bus from Front to Diridon Stationbus bus 17
    2. Take the bus from San Jose Diridon Station to Los Angeles Union Stationbus bus
    3. Take the bus from Downtown Los Angeles to Hesperia, CAbus bus
    12h 48m
    $92–180

  2. Drive 372.9 mi

    cheapest
    1. Drive from Santa Cruz to Hesperiacar car 372.9 mi
    7h 5m
    $69–99

  3. Bus, train

    1. Take the bus from Front to Diridon Stationbus bus 17
    2. Take the train from San Jose to Los Angelestrain train
    3. Take the train from Los Angeles to Victorville Amtraktrain train
    16h 37m
    $204–409

  4. Bus to Norman Y. Mineta San José International Airport, fly to Ontario International Airport, bus

    1. Take the bus from Front to Diridon Stationbus bus
    2. Fly from Norman Y. Mineta San José International Airport (SJC) to Ontario International Airport (ONT)plane plane SJC - ONT
    3. Take the bus from 285 S East End Ave - Pomona to Hesperia, CAbus bus
    8h 4m
    $228–888

  5. Bus

    1. Take the bus from Ocean & Water to Diridon Stationbus bus 17
    2. Take the bus from San Jose Diridon to Gilroy Transit Centerbus bus 68
    3. Take the bus from Gilroy to 285 S East End Ave - Pomonabus bus
    4. Take the bus from 285 S East End Ave - Pomona to Hesperia, CAbus bus
    15h 45m
    $117–180

  6. Bus to Norman Y. Mineta San José International Airport, fly to Burbank Bob Hope Airport, bus

    1. Take the bus from Front to Diridon Stationbus bus
    2. Fly from Norman Y. Mineta San José International Airport (SJC) to Burbank Bob Hope Airport (BUR)plane plane SJC - BUR
    3. Take the bus from Downtown Los Angeles to Hesperia, CAbus bus
    8h 16m
    $539–837

  7. Bus to Norman Y. Mineta San José International Airport, fly to Los Angeles International Airport, bus

    1. Take the bus from Front to Diridon Stationbus bus
    2. Fly from Norman Y. Mineta San José International Airport (SJC) to Los Angeles International Airport (LAX)plane plane SJC - LAX
    3. Take the bus from Downtown Los Angeles to Hesperia, CAbus bus
    8h 22m
    $156–700

  8. Bus, Caltrain to San Francisco International Airport, fly to Ontario International Airport

    1. Take the bus from Front to Diridon Stationbus bus
    2. Take the train from San Jose Diridon Caltrain Northbound to Millbrae Caltrain Northboundtrain train
    3. Fly from San Francisco International Airport (SFO) to Ontario International Airport (ONT)plane plane SFO - ONT
    4. Take the bus from 285 S East End Ave - Pomona to Hesperia, CAbus bus
    8h 53m
    $127–470

  9. Bus, train to Oakland International Airport, fly to Ontario International Airport

    1. Take the bus from Front to Diridon Stationbus bus
    2. Take the train from San Jose to Oakland Coliseum/Airport Amtraktrain train
    3. Fly from Oakland International Airport (OAK) to Ontario International Airport (ONT)plane plane OAK - ONT
    4. Take the bus from 285 S East End Ave - Pomona to Hesperia, CAbus bus
    9h 34m
    $296–858

  10. Bus to Norman Y. Mineta San José International Airport, fly to Long Beach Airport, bus

    1. Take the bus from Front to Diridon Stationbus bus
    2. Fly from Norman Y. Mineta San José International Airport (SJC) to Long Beach Airport (LGB)plane plane SJC - LGB
    3. Take the bus from Downtown Los Angeles to Hesperia, CAbus bus
    9h 37m
    $81–263

  11. Bus to Norman Y. Mineta San José International Airport, fly to John Wayne Airport Orange County, train

    1. Take the bus from Front to Diridon Stationbus bus
    2. Fly from Norman Y. Mineta San José International Airport (SJC) to John Wayne Airport Orange County (SNA)plane plane SJC - SNA
    3. Take the train from Fullerton Amtrak Station to Victorville Amtraktrain train
    11h 36m
    $239–894

Santa Cruz to Hesperia by bus and foot

Calendar14Weekly Services
Duration12h 48mAverage Duration
Ticket$92Cheapest Price
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Questions & Answers

Map of how to get from Santa Cruz to Hesperia.ExpandLaunch map view
  • Distance: 463.5 mi
  • Duration: 12h 48m

What companies run services between Santa Cruz, CA, USA and Hesperia, CA, USA?

You can take a bus from Front to Main St EB & 3rd Ave via Diridon Station, San Jose Diridon Station, Patsaouras Transit Plaza at Union Station, Spring St & 7th St, Downtown Los Angeles, Hesperia, CA, and Main St EB & Escondido Ave NS in around 12h 48m.

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