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How to get fromSanta Cruz to Irvineby bus, plane, train, car, or bus (Amtrak, Greyhound)

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There are 7 ways to get from Santa Cruz to Irvine by bus, plane, train, car, or bus (Amtrak, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Norman Y. Mineta San José International Airport, fly

    best
    1. Take the bus from Front to Diridon Stationbus bus
    2. Fly from Norman Y. Mineta San José International Airport (SJC) to John Wayne Airport Orange County (SNA)plane plane SJC - SNA
    3h 53m
    $206–823

  2. Bus via Westminster, CA - ABC Supermarket

    cheapest
    1. Take the bus from Ocean & Water to Diridon Stationbus bus 17
    2. Take the bus from San Jose, CA - Huong Lan Sandwich to Westminster, CA - ABC Supermarketbus bus San Jose
    11h 5m
    $53–78

  3. Bus, train

    1. Take the bus from Front to Diridon Stationbus bus 17
    2. Take the train from San Jose to Los Angelestrain train
    3. Take the train from L.A. Union Station to Tustintrain train
    14h 39m
    $148–306

  4. Drive 378.2 mi

    1. Drive from Santa Cruz to Irvinecar car 378.2 mi
    6h 38m
    $69–100

  5. Bus, Caltrain to San Francisco International Airport, fly

    1. Take the bus from Front to Diridon Stationbus bus
    2. Take the train from San Jose Diridon Caltrain Northbound to Millbrae Caltrain Northboundtrain train
    3. Fly from San Francisco International Airport (SFO) to John Wayne Airport Orange County (SNA)plane plane SFO - SNA
    4h 50m
    $205–735

  6. Bus, train to Oakland International Airport, fly

    1. Take the bus from Front to Diridon Stationbus bus
    2. Take the train from San Jose to Oakland Coliseum/Airport Amtraktrain train
    3. Fly from Oakland International Airport (OAK) to John Wayne Airport Orange County (SNA)plane plane OAK - SNA
    5h 24m
    $264–793

  7. Bus

    1. Take the bus from Front to Diridon Stationbus bus 17
    2. Take the bus from San Jose Diridon Station to Anaheim Regional Transportation Intermodal Centerbus bus Greyhound US0831
    12h 1m
    $67–126

Santa Cruz to Irvine by bus

Calendar14Weekly Buses
Duration11h 5mAverage Duration
Ticket$53Cheapest Price
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Questions & Answers

Map of how to get from Santa Cruz to Irvine.ExpandLaunch map view
  • Distance: 379.4 mi
  • Duration: 3h 53m

What companies run services between Santa Cruz, CA, USA and Irvine, CA, USA?

You can take a bus from Ocean & Water to Culver-San Leandro via Diridon Station, San Jose Diridon, Santa Clara & 1st, Tully & King, San Jose, CA - Huong Lan Sandwich, Westminster, CA - ABC Supermarket, Bolsa-Magnolia, and 1St-Centennial in around 11h 5m.

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