Rome2Rio

How to get fromSanta Cruz to Louisvilleby taxi, plane, bus (Amtrak, Greyhound, Flixbus), bus, train, or car

Find Transport to Louisville

See all options

There are 7 ways to get from Santa Cruz to Louisville by taxi, plane, bus (Amtrak, Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Monterey Regional Airport, fly

    best
    1. Take the taxi from Santa Cruz to Monterey Regional Airport (MRY)taxi taxi
    2. Fly from Monterey Regional Airport (MRY) to Louisville International Airport (SDF)plane plane MRY - SDF
    8h 30m
    $365–1,123

  2. Bus, Caltrain to San Francisco International Airport, fly

    cheapest
    1. Take the bus from Front to Diridon Stationbus bus
    2. Take the train from San Jose Diridon Caltrain Northbound to Millbrae Caltrain Northboundtrain train
    3. Fly from San Francisco International Airport (SFO) to Louisville International Airport (SDF)plane plane SFO - SDF
    8h 52m
    $226–638

  3. Bus

    1. Take the bus from Front to Diridon Stationbus bus 17
    2. Take the bus from San Jose Diridon Station to Los Angeles Union Stationbus bus
    3. Take the bus from Los Angeles Union Station to St Louis Bus Stationbus bus
    4. Take the bus from St Louis Bus Station to Evansville Bus Stationbus bus
    5. Take the bus from Evansville, IN to Louisville, KYbus bus
    2d 9h
    $399–769

  4. Bus, train

    1. Take the bus from Ocean & Water to Diridon Stationbus bus 17
    2. Take the bus from San Jose to Emeryvillebus bus
    3. Take the train from Emeryville to Chicago Union Stationtrain train
    4. Take the bus from Chicago Union Station to Louisville, KYbus bus
    2d 16h
    $821–1,694

  5. Drive 2,323 mi

    1. Drive from Santa Cruz to Louisvillecar car 2,323 mi
    37h 36m
    $424–613

  6. Bus to Norman Y. Mineta San José International Airport, fly

    1. Take the bus from Front to Diridon Stationbus bus
    2. Fly from Norman Y. Mineta San José International Airport (SJC) to Louisville International Airport (SDF)plane plane SJC - SDF
    10h
    $237–976

  7. Bus, train to Oakland International Airport, fly

    1. Take the bus from Front to Diridon Stationbus bus
    2. Take the train from San Jose to Oakland Coliseum/Airport Amtraktrain train
    3. Fly from Oakland International Airport (OAK) to Louisville International Airport (SDF)plane plane OAK - SDF
    11h 5m
    $245–996

Santa Cruz to Louisville by bus

Calendar7Weekly Buses
Duration2d 9hAverage Duration
Ticket$399Cheapest Price
See schedules

Questions & Answers

Map of how to get from Santa Cruz to Louisville.ExpandLaunch map view
  • Distance: 2,021.2 mi
  • Duration: 8h 30m

What companies run services between Santa Cruz, CA, USA and Louisville, KY, USA?

You can take a bus from Front to Louisville, KY via Diridon Station, San Jose Diridon Station, Los Angeles Union Station, St Louis Bus Station, and Evansville, IN in around 2d 9h.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers