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How to get fromSanta Cruz to Cuscoby bus, plane, or car

Find Transport to Cusco

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There are 4 ways to get from Santa Cruz to Cusco by bus, plane, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, fly

    best
    1. Take the bus from Hospital to Terminal Sur de Santiagobus bus
    2. Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Alejandro Velasco Astete International Airport (CUZ)plane plane SCL - CUZ
    9h 3m
    $173–361

  2. Bus

    cheapest
    1. Take the bus from Terminal de Buses Santa Cruz to Terminal Sur de Santiagobus bus
    2. Take the bus from Terminal San Borja to Terminal Rodoviario de Aricabus bus
    3. Take the bus from Terminal Internacional to Tacnabus bus
    4. Take the bus from Tacna Bus Station to Cusco Bus Stationbus bus
    2d 3h
    $94–192

  3. Drive 3,003.5 km

    1. Drive from Santa Cruz to Cuscocar car 3,003.5 km
    40h 9m
    $452–653

  4. Bus via Oruro Airport (ORU)

    1. Take the bus from Hospital to Terminal Sur de Santiagobus bus
    2. Take the bus from Terminal Alameda - Turbus to Orurobus bus
    3. Take the bus from Oruro to La Pazbus bus
    4. Take the bus from La Paz to Cuscobus bus
    2d 9h
    $106–124

Comodoro Arturo Merino Benítez International Airport (SCL) to Alejandro Velasco Astete International Airport (CUZ) flights

Calendar71Weekly Planes
Duration6h 21mAverage Duration
Ticket$133Cheapest Price
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Questions & Answers

Map of how to get from Santa Cruz to Cusco.ExpandLaunch map view
  • Distance: 2,444.9 km
  • Duration: 9h 3m

What companies run services between Santa Cruz, O'Higgins, Chile and Cusco, Peru?

You can take a bus from Terminal de Buses Santa Cruz to Cusco Bus Station via Terminal Sur de Santiago, Terminal San Borja, Terminal Rodoviario de Arica, Terminal Internacional, and Tacna Bus Station in around 2d 3h.

Airlines
Bus operators

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