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How to get fromSanta Cruz to Mendozaby bus (Flixbus), car, bus, plane, or train

Find Transport to Mendoza

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There are 6 ways to get from Santa Cruz to Mendoza by bus (Flixbus), car, bus, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Santa Cruz to Terminal Sur de Santiagobus bus FlixBus CL027
    2. Take the bus from Terminal Alameda - Turbus to Terminal Mendozabus bus Santiago
    9h 44m
    $36,701–157,533

  2. Bus #2

    cheapest
    1. Take the bus from Terminal de Buses Santa Cruz to Terminal Sur de Santiagobus bus Santiago
    2. Take the bus from Terminal Sur de Santiago to Terminal Mendozabus bus Santiago
    11h
    $28,321–78,382

  3. Drive 517.6 km

    1. Drive from Santa Cruz to Mendozacar car 517.6 km
    6h 44m
    $95,565–138,038

  4. Bus, fly

    1. Take the bus from Santa Cruz to Terminal Sur de Santiagobus bus
    2. Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Governor Francisco Gabrielli International Airport (MDZ)plane plane SCL - MDZ
    6h 45m
    $153,237–412,069

  5. Bus via Potrerillos

    1. Take the bus from Hospital to Terminal Sur de Santiagobus bus
    2. Take the bus from Terminal Sur de Santiago to Potrerillosbus bus
    3. Take the bus from Potrerillos to Terminal Mendozabus bus
    9h 50m
    $67,353–81,954

  6. Bus, train

    1. Take the bus from Santa Cruz to San Fernandobus bus
    2. Take the train from San Fernando to Estacion Central Alamedatrain train
    3. Take the bus from Terminal Alameda - Turbus to Terminal Mendozabus bus
    10h 54m
    $36,122–161,457

Comodoro Arturo Merino Benítez International Airport (SCL) to Governor Francisco Gabrielli International Airport (MDZ) flights

Calendar28Weekly Planes
Duration1h 5mAverage Duration
Ticket$84,812Cheapest Price
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Questions & Answers

Map of how to get from Santa Cruz to Mendoza.ExpandLaunch map view
  • Distance: 537.9 km
  • Duration: 9h 44m

What companies run services between Santa Cruz, O'Higgins, Chile and Mendoza, Argentina?

You can take a bus from Santa Cruz to Terminal Mendoza via Terminal Sur de Santiago and Terminal Alameda - Turbus in around 9h 44m.

Airlines
Train operators
Bus operators

Want to know more about travelling around the world?

Rome2Rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including How to plan an amazing trip around Scandinavia, Train travel in France: A guide to SNCF, and Why you should take the train in the US - to help you get the most out of your next trip.

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