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How to get fromSanta Cruz to Santiagoby bus (Flixbus), bus, train, car, or taxi

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There are 5 ways to get from Santa Cruz to Santiago by bus (Flixbus), bus, train, car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Hospital to Terminal Sur de Santiagobus bus Santiago
    2h 42m
    $4–35

  2. Bus, train

    1. Take the bus from Santa Cruz to San Fernandobus bus FlixBus CL027 / ...
    2. Take the train from San Fernando to Estacion Central Alamedatrain train San Fernando / ...
    3h 42m
    $10–36

  3. Drive 180 km

    1. Drive from Santa Cruz to Santiagocar car 180 km
    2h 4m
    $23–33

  4. Taxi

    1. Take the taxi from Santa Cruz to Santiagotaxi taxi 180 km
    2h 4m
    $140–170

  5. Bus via Marchihue

    1. Take the bus from Marchihue to Terminal Sur de Santiagobus bus Santiago / ...
    4h 32m
    $5–19

Santa Cruz to Santiago by bus

Calendar977Weekly Buses
Duration2h 42mAverage Duration
Ticket$4Cheapest Price
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Questions & Answers

Map of how to get from Santa Cruz to Santiago.ExpandLaunch map view
  • Distance: 217.6 km
  • Duration: 2h 42m

What companies run services between Santa Cruz, O'Higgins, Chile and Santiago, Chile?

Andimar operates a bus from Hospital to Terminal Sur de Santiago hourly. Tickets cost $4–13 and the journey takes 2h 42m. Five other operators also service this route.

Train operators
Bus operators
Other operators

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