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How to get fromSanta Cruz to Uyuniby bus, plane, bus (Flixbus), car, shuttle, or helicopter

Find Transport to Uyuni

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There are 6 ways to get from Santa Cruz to Uyuni by bus, plane, bus (Flixbus), car, shuttle, or helicopter

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, fly to Uyuni Airport

    best
    1. Take the bus from Santa Cruz to Terminal Sur de Santiagobus bus
    2. Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Uyuni Airport (UYU)plane plane SCL - UYU
    13h 59m
    $425–818

  2. Bus

    cheapest
    1. Take the bus from Santa Cruz to Terminal Sur de Santiagobus bus
    2. Take the bus from Terminal Alameda - Turbus to Terminal Rodoviario Calamabus bus
    3. Take the bus from Terminal Rodoviario Calama to Uyunibus bus
    32h 29m
    $74–145

  3. Drive 2,068.7 km

    1. Drive from Santa Cruz to Uyunicar car 2,068.7 km
    26h 19m
    $256–369

  4. Bus, fly to Calama Airport, shuttle, Tour

    1. Take the bus from Santa Cruz to Terminal Sur de Santiagobus bus
    2. Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Calama Airport (CJC)plane plane SCL - CJC
    3. Take a shuttle bus from Calama Airport to San Pedro de Atacamashuttle bus
    4. Take a shuttle bus from San Pedro de Atacama to Uyunishuttle bus
    12h 13m
    $479–630

  5. Bus, fly to Antofagasta Airport, helicopter, Tour

    1. Take the bus from Santa Cruz to Terminal Sur de Santiagobus bus
    2. Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Antofagasta Airport (ANF)plane plane SCL - ANF
    3. Take the helicopter from Antofagasta Airport to San Pedro de Atacama Airporthelicopter helicopter
    4. Take a shuttle bus from San Pedro de Atacama to Uyunishuttle bus
    12h 15m
    $9,234–9,400

  6. Bus via Santiago

    1. Take the bus from Terminal de Buses Santa Cruz to Terminal Sur de Santiagobus bus
    2. Take the bus from Santiago to Calamabus bus
    3. Take the bus from Terminal Rodoviario Calama to Uyunibus bus
    33h 51m
    $182–310

Comodoro Arturo Merino Benítez International Airport (SCL) to Uyuni Airport (UYU) flights

Calendar4Weekly Planes
Duration8h 20mAverage Duration
Ticket$339Cheapest Price
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Questions & Answers

Map of how to get from Santa Cruz to Uyuni.ExpandLaunch map view
  • Distance: 1,696.5 km
  • Duration: 13h 59m

What companies run services between Santa Cruz, O'Higgins, Chile and Uyuni, Potosí, Bolivia?

You can take a bus from Santa Cruz to Uyuni via Terminal Sur de Santiago, Terminal Alameda - Turbus, and Terminal Rodoviario Calama in around 32h 29m.

Airlines
Bus operators

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