There are 5 ways to get from Santa Fe Depot to Los Angeles by train (Amtrak), bus (Amtrak), car, plane, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Amtrak)
best- Take the train from San Diego to Los Angelestrain Pacific Surfliner
2h 56m$40–85Bus via San Diego
cheapest- Take the bus from San Diego to Los Angeles Union Station Arrivalsbus FlixBus 2017
3h 54m$21–40Bus (Amtrak)
- Take the bus from San Diego to Los Angelesbus Amtrak Thruway Connecting Service
3h 20m$40–65Drive 120.1 mi
- Drive from Santa Fe Depot to Los Angelescar 120.1 mi
2h 7m$22–32Fly
- Fly from San Diego International Airport (SAN) to Los Angeles International Airport (LAX)plane SAN - LAX
3h 14m$160–818
Santa Fe Depot to Los Angeles by train (Amtrak)
Questions & Answers
The cheapest way to get from Santa Fe Depot to Los Angeles is to bus via San Diego which costs $21 - $40 and takes 3h 54m.
The fastest way to get from Santa Fe Depot to Los Angeles is to drive which takes 2h 7m and costs $21 - $35.
Yes, there is a direct bus departing from San Diego and arriving at Los Angeles. Services depart once daily, and operate every day. The journey takes approximately 3h 20m.
Yes, there is a direct train departing from San Diego and arriving at Los Angeles. Services depart hourly, and operate every day. The journey takes approximately 2h 56m.
The distance between Santa Fe Depot and Los Angeles is 127 miles. The road distance is 120.8 miles.
The best way to get from Santa Fe Depot to Los Angeles without a car is to train which takes 2h 56m and costs $40 - $85.
The train from San Diego to Los Angeles takes 2h 56m including transfers and departs hourly.
Santa Fe Depot to Los Angeles bus services, operated by Amtrak, depart from San Diego station.
Santa Fe Depot to Los Angeles train services, operated by Amtrak, depart from San Diego station.
The best way to get from Santa Fe Depot to Los Angeles is to train which takes 2h 56m and costs $40 - $85. Alternatively, you can bus, which costs $40 - $65 and takes 3h 20m, you could also fly, which costs $160 - $850 and takes 3h 14m.
What companies run services between Santa Fe Depot, San Diego County, CA, USA and Los Angeles, CA, USA?
Amtrak operates a train from San Diego to Los Angeles hourly. Tickets cost $40–85 and the journey takes 2h 56m. Alternatively, Amtrak operates a bus from San Diego to Los Angeles once daily. Tickets cost $40–65 and the journey takes 3h 20m.
- Website
- delta.com
Flights from San Diego International Airport to Los Angeles International Airport
- Ave. Duration
- 1h 14m
- When
- Every day
- Estimated price
- $24–180
- Website
- united.com
Flights from San Diego International Airport to Los Angeles International Airport
- Ave. Duration
- 1h 3m
- When
- Every day
- Estimated price
- $24–180
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from San Diego to Los Angeles
- Ave. Duration
- 2h 56m
- Frequency
- Hourly
- Estimated price
- $40–85
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from San Diego to Los Angeles
- Ave. Duration
- 3h 20m
- Frequency
- Once daily
- Estimated price
- $40–65
- Website
- https://www.amtrak.com/home.html
- Website
- flixbus.com
Bus from San Diego to Los Angeles Union Station Arrivals
- Ave. Duration
- 3h 45m
- Frequency
- Once daily
- Schedules at
- flixbus.com
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from San Diego to Los Angeles Union Station Arrivals
- Ave. Duration
- 3h 45m
- Frequency
- Once daily
- Estimated price
- $21–40
- Schedules at
- flixbus.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
Santa Fe Depot to Los Angeles bus services, operated by Amtrak, arrive at Los Angeles station.
Santa Fe Depot to Los Angeles train services, operated by Amtrak, arrive at Los Angeles station.
Yes, the driving distance between Santa Fe Depot to Los Angeles is 121 miles. It takes approximately 2h 7m to drive from Santa Fe Depot to Los Angeles.
Book your Santa Fe Depot to Los Angeles train tickets online with Omio.
Book your Santa Fe Depot to Los Angeles bus tickets online with Omio.
There are 3405+ hotels available in Los Angeles.







