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How to get fromSanta Fe Depot to Yumaby bus (Greyhound), train (Amtrak), car, plane, or bus

Find Transport to Yuma

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There are 5 ways to get from Santa Fe Depot to Yuma by bus (Greyhound), train (Amtrak), car, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from El Cajon Transit Center to Yuma County Area Transitbus bus Greyhound US0851S
    5h 23m
    $48–85

  2. Drive 169.8 mi

    cheapest
    1. Drive from Santa Fe Depot to Yumacar car 169.8 mi
    2h 46m
    $31–45

  3. Train (Amtrak)

    1. Take the train from San Diego to Los Angelestrain train Pacific Surfliner
    2. Take the train from Los Angeles to Yuma Amtraktrain train Texas Eagle / ...
    8h 43m
    $121–253

  4. Fly

    1. Fly from San Diego International Airport (SAN) to Yuma International Airport (YUM)plane plane SAN - YUM
    5h 52m
    $58–327

  5. Bus via Tijuana

    1. Take the bus from Tijuana to San Luis Río Coloradobus bus
    2. Take the bus from William Brook Ave @ B Street to 1st Street @ 4th Avenuebus bus 95
    8h 27m
    $36–97

Santa Fe Depot to Yuma by tram and bus

Calendar12Weekly Services
Duration5h 23mAverage Duration
Ticket$48Cheapest Price
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Questions & Answers

Map of how to get from Santa Fe Depot to Yuma.ExpandLaunch map view
  • Distance: 188.4 mi
  • Duration: 5h 23m

What companies run services between Santa Fe Depot, San Diego County, CA, USA and Yuma, AZ, USA?

Greyhound USA operates a bus from El Cajon Transit Center to Yuma County Area Transit once daily. Tickets cost $27–55 and the journey takes 3h 35m. Jefferson Lines also services this route 5 times a week. Alternatively, you can take a train from San Diego to Yuma Amtrak via Los Angeles in around 8h 43m.

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