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How to get fromSanta Fe to Chicagoby plane, train (Amtrak), bus (Greyhound, Flixbus), car, or train

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There are 5 ways to get from Santa Fe to Chicago by plane, train (Amtrak), bus (Greyhound, Flixbus), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Santa Fe Municipal Airport to Chicago O'Hare International Airport

    best
    1. Fly from Santa Fe Municipal Airport (SAF) to Chicago O'Hare International Airport (ORD)plane plane SAF - ORD
    4h 15m
    $103–410

  2. Train (Amtrak)

    1. Take the train from Lamy Station to Chicago Union Stationtrain train Southwest Chief
    26h 28m
    $416–859

  3. Bus

    1. Take the bus from Santa Fe to Albuquerquebus bus
    2. Take the bus from Albuquerque Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Chicago Bus Stationbus bus
    31h 39m
    $244–434

  4. Drive 1,254.5 mi

    1. Drive from Santa Fe to Chicagocar car 1,254.5 mi
    21h 34m
    $229–331

  5. Train to Albuquerque International Airport, fly to Chicago Midway International Airport

    1. Take the train from Santa Fe Depot Rail Runner Station to Downtown Albuquerque Rail Runner Stationtrain train
    2. Fly from Albuquerque International Airport (ABQ) to Chicago Midway International Airport (MDW)plane plane ABQ - MDW
    7h
    $118–564

Santa Fe to Chicago by bus and train (Amtrak)

Calendar7Weekly Services
Duration26h 28mAverage Duration
Ticket$416Cheapest Price
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Questions & Answers

Map of how to get from Santa Fe to Chicago.ExpandLaunch map view
  • Distance: 1,098.3 mi
  • Duration: 4h 15m

What companies run services between Santa Fe, NM, USA and Chicago, IL, USA?

American Airlines and United Airlines fly from Santa Fe Municipal Airport (SAF) to Chicago O'Hare International Airport (ORD) every 2 hours. Alternatively, Amtrak operates a train from Lamy Station to Chicago Union Station once daily. Tickets cost $410–850 and the journey takes 24h 56m.

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