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How to get fromSanta Fe to Indianapolisby plane, bus (Greyhound), train, bus, or car

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There are 5 ways to get from Santa Fe to Indianapolis by plane, bus (Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Santa Fe Municipal Airport

    best
    1. Fly from Santa Fe Municipal Airport (SAF) to Indianapolis (IND)plane plane SAF - IND
    6h 14m
    $183–777

  2. Bus

    1. Take the bus from Santa Fe to Albuquerquebus bus
    2. Take the bus from Albuquerque Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Indianapolis Union Stationbus bus
    29h 59m
    $219–404

  3. Train, bus

    1. Take the train from Lamy Station to Chicago Union Stationtrain train Southwest Chief
    2. Take the bus from Chicago Bus Station to Indianapolisbus bus FlixBus 2511 / ...
    31h 22m
    $435–909

  4. Drive 1,233.5 mi

    1. Drive from Santa Fe to Indianapoliscar car 1,233.5 mi
    20h 57m
    $226–326

  5. Train to Albuquerque International Airport, fly

    1. Take the train from Santa Fe Depot Rail Runner Station to Downtown Albuquerque Rail Runner Stationtrain train
    2. Fly from Albuquerque International Airport (ABQ) to Indianapolis (IND)plane plane ABQ - IND
    9h 34m
    $198–911

Santa Fe to Indianapolis by bus, train, and foot

Calendar7Weekly Services
Duration31h 22mAverage Duration
Ticket$435Cheapest Price
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Questions & Answers

Map of how to get from Santa Fe to Indianapolis.ExpandLaunch map view
  • Distance: 1,141.1 mi
  • Duration: 6h 14m

What companies run services between Santa Fe, NM, USA and Indianapolis, IN, USA?

United Airlines and American Airlines fly from Santa Fe Municipal Airport (SAF) to Indianapolis (IND) every 4 hours. Alternatively, you can take a bus from Downtown Transit Center to Indianapolis Union Station via Santa Fe, Albuquerque, Albuquerque Bus Station, and St Louis Bus Station in around 29h 59m.

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