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How to get fromSanta Fe to Lexingtonby plane, car, train, or bus

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There are 8 ways to get from Santa Fe to Lexington by plane, car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Santa Fe Municipal Airport to Louisville International Airport, drive

    best
    1. Fly from Santa Fe Municipal Airport (SAF) to Louisville International Airport (SDF)plane plane SAF - SDF
    2. Drive from Louisville-Airport-SDF to Lexingtoncar car
    6h 57m
    $195–796

  2. Train, bus, drive

    1. Take the train from Santa Fe Depot Rail Runner Station to Downtown Albuquerque Rail Runner Stationtrain train
    2. Take the bus from Albuquerque Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Evansville Bus Stationbus bus
    4. Take the bus from Evansville, IN to Corydon, INbus bus
    5. Drive from Middletown Station @ Target to Lexingtoncar car
    34h 24m
    $283–504

  3. Train, bus, drive via Kansas City

    1. Take the train from Lamy Station to Kansas Citytrain train
    2. Take the train from Kansas City to St. Louistrain train
    3. Take the bus from St Louis Bus Station to Evansville Bus Stationbus bus
    4. Take the bus from Evansville, IN to Corydon, INbus bus
    5. Drive from Middletown Station @ Target to Lexingtoncar car
    35h 36m
    $478–945

  4. Drive 1,336.5 mi

    1. Drive from Santa Fe to Lexingtoncar car 1,336.5 mi
    22h 46m
    $244–353

  5. Fly Santa Fe Municipal Airport to Covington, drive

    1. Fly from Santa Fe Municipal Airport (SAF) to Covington (CVG)plane plane SAF - CVG
    2. Drive from Covington (CVG) to Lexingtoncar car
    6h 57m
    $216–847

  6. Fly Santa Fe Municipal Airport to Blue Grass Airport

    1. Fly from Santa Fe Municipal Airport (SAF) to Blue Grass Airport (LEX)plane plane SAF - LEX
    7h 49m
    $263–1,127

  7. Train to Albuquerque International Airport, fly to Louisville International Airport, drive

    1. Take the train from Santa Fe Depot Rail Runner Station to Downtown Albuquerque Rail Runner Stationtrain train
    2. Fly from Albuquerque International Airport (ABQ) to Louisville International Airport (SDF)plane plane ABQ - SDF
    3. Drive from Louisville-Airport-SDF to Lexingtoncar car
    10h 10m
    $210–930

  8. Train, bus, drive via Chicago (Amtrak)

    1. Take the train from Lamy Station to Chicago Union Stationtrain train
    2. Take the bus from Chicago Union Station to Louisville, KYbus bus
    3. Drive from Middletown Station @ Target to Lexingtoncar car
    38h 57m
    $470–943

Santa Fe Municipal Airport (SAF) to Louisville International Airport (SDF) flights

Calendar44Weekly Planes
Duration6h 20mAverage Duration
Ticket$166Cheapest Price
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Questions & Answers

Map of how to get from Santa Fe to Lexington.ExpandLaunch map view
  • Distance: 1,225.2 mi
  • Duration: 6h 57m

What companies run services between Santa Fe, NM, USA and Lexington, KY, USA?

American Airlines and United Airlines fly from Santa Fe Municipal Airport (SAF) to Blue Grass Airport (LEX) 4 times a day.

Airlines
Train operators
Bus operators

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