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How to get fromSanta Fe to San Diegoby plane, train (Amtrak), bus (Greyhound, Flixbus), car, train, or bus

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There are 6 ways to get from Santa Fe to San Diego by plane, train (Amtrak), bus (Greyhound, Flixbus), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Santa Fe Municipal Airport

    best
    1. Fly from Santa Fe Municipal Airport (SAF) to San Diego International Airport (SAN)plane plane SAF - SAN
    3h 59m
    $96–425

  2. Train

    1. Take the train from Santa Fe Depot Rail Runner Station to Downtown Albuquerque Rail Runner Stationtrain train
    2. Take the train from Albuquerque Alvarado Transportation Center to Fullerton Amtrak Stationtrain train
    3. Take the train from Fullerton Amtrak Station to San Diegotrain train
    22h 31m
    $296–678

  3. Bus

    1. Take the bus from Santa Fe to Albuquerquebus bus
    2. Take the bus from Albuquerque Bus Station to Los Angeles Union Stationbus bus
    3. Take the bus from Los Angeles Union Station to San Diegobus bus
    26h 14m
    $174–319

  4. Drive 824.2 mi

    1. Drive from Santa Fe to San Diegocar car 824.2 mi
    13h 57m
    $151–218

  5. Train to Albuquerque International Airport, fly

    1. Take the train from Santa Fe Depot Rail Runner Station to Downtown Albuquerque Rail Runner Stationtrain train
    2. Fly from Albuquerque International Airport (ABQ) to San Diego International Airport (SAN)plane plane ABQ - SAN
    5h 28m
    $506–759

  6. Bus via Las Cruces

    1. Take the bus from Santa Fe - Dulceria to Las Cruces, NMbus bus Denver to El Paso
    2. Take the bus from Las Cruces, NM to Cross Border Express, San Diegobus bus El Paso
    30h 18m
    $190–317

Santa Fe to San Diego by train

Calendar7Weekly Trains
Duration22h 31mAverage Duration
Ticket$296Cheapest Price
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Questions & Answers

Map of how to get from Santa Fe to San Diego.ExpandLaunch map view
  • Distance: 675.6 mi
  • Duration: 3h 59m

What companies run services between Santa Fe, NM, USA and San Diego, CA, USA?

American Airlines and United Airlines fly from Santa Fe Municipal Airport (SAF) to San Diego International Airport (SAN) every 4 hours. Alternatively, you can take a train from Santa Fe Depot Rail Runner Station to San Diego via Downtown Albuquerque Rail Runner Station, Albuquerque Alvarado Transportation Center, and Fullerton Amtrak Station in around 22h 31m.

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