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How to get fromSanta Fe to West Lafayetteby plane, train, bus, bus (Greyhound), or car

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There are 7 ways to get from Santa Fe to West Lafayette by plane, train, bus, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Santa Fe Municipal Airport to Purdue University Airport

    best
    1. Fly from Santa Fe Municipal Airport (SAF) to Purdue University Airport (LAF)plane plane SAF - LAF
    6h 19m
    $122–526

  2. Train, bus (Amtrak)

    1. Take the train from Lamy Station to Chicago Union Stationtrain train Southwest Chief
    2. Take the bus from Chicago Union Station to Lafayette Amtrak Stationbus bus Chicago
    29h 58m
    $419–903

  3. Bus

    1. Take the bus from Santa Fe to Albuquerquebus bus
    2. Take the bus from Albuquerque Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Indianapolis Union Stationbus bus
    4. Take the bus from Indianapolis Union Station to Lafayette Bus Stopbus bus
    32h 34m
    $228–422

  4. Drive 1,236.7 mi

    1. Drive from Santa Fe to West Lafayettecar car 1,236.7 mi
    21h 8m
    $226–326

  5. Fly Santa Fe Municipal Airport to Indianapolis, bus

    1. Fly from Santa Fe Municipal Airport (SAF) to Indianapolis (IND)plane plane SAF - IND
    2. Take the bus from Indianapolis Airport to Purdue Memorial Unionbus bus
    7h 22m
    $199–765

  6. Fly Santa Fe Municipal Airport to Chicago O'Hare International Airport, train

    1. Fly from Santa Fe Municipal Airport (SAF) to Chicago O'Hare International Airport (ORD)plane plane SAF - ORD
    2. Take the train from Chicago Union Station to Lafayette Amtrak Stationtrain train
    8h 29m
    $138–500

  7. Train to Albuquerque International Airport, fly to Purdue University Airport

    1. Take the train from Santa Fe Depot Rail Runner Station to Downtown Albuquerque Rail Runner Stationtrain train
    2. Fly from Albuquerque International Airport (ABQ) to Purdue University Airport (LAF)plane plane ABQ - LAF
    12h 50m
    $137–610

Santa Fe to West Lafayette by bus and train (Amtrak)

Calendar7Weekly Services
Duration29h 58mAverage Duration
Ticket$419Cheapest Price
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Questions & Answers

Map of how to get from Santa Fe to West Lafayette.ExpandLaunch map view
  • Distance: 1,103.2 mi
  • Duration: 6h 19m

What companies run services between Santa Fe, NM, USA and West Lafayette, IN, USA?

American Airlines and United Airlines fly from Santa Fe Municipal Airport (SAF) to Purdue University Airport (LAF) 3 times a day. Alternatively, you can take a bus from Downtown Transit Center to Lafayette Bus Stop via Santa Fe, Albuquerque, Albuquerque Bus Station, St Louis Bus Station, and Indianapolis Union Station in around 32h 34m.

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