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How to get fromSanta Fe to San Antonioby taxi, plane, bus (Flixbus), train, car, or bus

Find Transport to San Antonio

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There are 6 ways to get from Santa Fe to San Antonio by taxi, plane, bus (Flixbus), train, car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to William P. Hobby Airport, fly

    best
    1. Take the taxi from Santa Fe to Houston-Hobby-Apt-Airport-HOUtaxi taxi
    2. Fly from William P. Hobby Airport (HOU) to San Antonio International Airport (SAT)plane plane HOU - SAT
    2h 21m
    $158–686

  2. Drive 221.8 mi

    cheapest
    1. Drive from Santa Fe to San Antoniocar car 221.8 mi
    3h 50m
    $41–59

  3. Bus (Flixbus)

    1. Take the bus from Downtown Houston to San Antonio Bus Stationbus bus FlixBus 2212
    5h 16m
    $73–104

  4. Taxi, train (Amtrak)

    1. Take the taxi from Santa Fe to Houstontaxi taxi
    2. Take the train from Houston to San Antonio Stationtrain train Sunset Limited
    5h 52m
    $161–254

  5. Line 244 bus, line 102 bus to George Bush Intercontinental Airport, fly

    1. Take the bus from El Dorado Park & Ride to Travis St @ Texas Avebus bus
    2. Take the bus from Travis St @ Texas Ave to Bush IAH Terminal Cbus bus
    3. Fly from George Bush Intercontinental Airport (IAH) to San Antonio International Airport (SAT)plane plane IAH - SAT
    5h
    $103–471

  6. Bus via San Antonio, TX - E Commerce St

    1. Take the bus from Houston, TX - 808 Jefferson St to San Antonio, TX - E Commerce Stbus bus Houston
    5h 35m
    $89–149

William P. Hobby Airport (HOU) to San Antonio International Airport (SAT) flights

Calendar21Weekly Planes
Duration1hAverage Duration
Ticket$85Cheapest Price
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Questions & Answers

Map of how to get from Santa Fe to San Antonio.ExpandLaunch map view
  • Distance: 226.5 mi
  • Duration: 2h 21m

What companies run services between Santa Fe, TX, USA and San Antonio, TX, USA?

Flixbus USA operates a bus from Downtown Houston to San Antonio Bus Station 5 times a week. Tickets cost $29–50 and the journey takes 3h 10m.

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