There are 4 ways to get from Santa Fe to South Padre Island by taxi, plane, bus, car, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Taxi, fly
best- Take the taxi from Santa Fe to Houston-Hobby-Apt-Airport-HOUtaxi
- Fly from William P. Hobby Airport (HOU) to Rio Grande Valley International Airport (HRL)plane HOU - HRL
- Take the taxi from Rio Grande Valley International Airport (HRL) to South Padre Islandtaxi
2h 36m$241–684Drive 369.7 mi
cheapest- Drive from Santa Fe to South Padre Islandcar 369.7 mi
8h 11m$68–98Taxi, bus
- Take the taxi from Santa Fe to Houston - Telephone Rdtaxi
- Take the bus from Houston - Telephone Rd to Brownsville Bus Stationbus
- Take the taxi from Brownsville Bus Station to South Padre Islandtaxi
7h 36m$232–281Bus
- Take the bus from Houston Bus Station to La Plaza at Brownsvillebus FlixBus US1126
12h 3m$122–196
William P. Hobby Airport (HOU) to Rio Grande Valley International Airport (HRL) flights
Questions & Answers
The cheapest way to get from Santa Fe to South Padre Island is to drive which costs $65 - $100 and takes 8h 11m.
The fastest way to get from Santa Fe to South Padre Island is to taxi and fly which takes 2h 36m and costs $240 - $700.
No, there is no direct bus from Santa Fe to South Padre Island. However, there are services departing from El Dorado Park & Ride and arriving at Las Palmas Port Isabel via Eastwood Transit Center, Houston Bus Station and La Plaza at Brownsville. The journey, including transfers, takes approximately 12h 3m.
The distance between Santa Fe and South Padre Island is 345 miles. The road distance is 371.9 miles.
The best way to get from Santa Fe to South Padre Island without a car is to taxi and bus which takes 7h 36m and costs $230 - $290.
It takes approximately 2h 36m to get from Santa Fe to South Padre Island, including transfers.
Santa Fe to South Padre Island bus services, operated by Flixbus USA, depart from Houston Bus Station.
Santa Fe to South Padre Island bus services, operated by Flixbus USA, arrive at La Plaza at Brownsville station.
Yes, the driving distance between Santa Fe to South Padre Island is 372 miles. It takes approximately 8h 11m to drive from Santa Fe to South Padre Island.
There are 872+ hotels available in South Padre Island.
What companies run services between Santa Fe, TX, USA and South Padre Island, TX, USA?
Flixbus USA operates a bus from Houston Bus Station to La Plaza at Brownsville once daily. Tickets cost $60–110 and the journey takes 7h 45m. Greyhound USA also services this route 5 times a week.
- Website
- southwest.com
Flights from William P. Hobby Airport to Rio Grande Valley International Airport
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- $70–470
- Phone
- +1 800-923-1799
- [email protected]
- Website
- Omnibus Express
Bus from Houston - Telephone Rd to Brownsville Bus Station
- Ave. Duration
- 6h 25m
- Frequency
- 3 times a day
- Estimated price
- $75–95
- Schedules at
- Omnibus Express
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Houston Bus Station to La Plaza at Brownsville
- Ave. Duration
- 7h 45m
- Frequency
- Once daily
- Estimated price
- $60–110
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Houston Bus Station to La Plaza at Brownsville
- Ave. Duration
- 9h 20m
- Frequency
- 5 times a week
- Estimated price
- $60–120
- Website
- Greyhound
- Ave. Duration
- 40 min
- Estimated price
- $70–130
Ubeda Transportation
- Phone
- +1 956-601-7794
Taxi
- Phone
- +52868 307 0507
- Website
- facebook.com
Taxi Línea Rosa Matamoros
- Phone
- +52 868 312 2393
- Website
- facebook.com
Taxi Matamoros
- Phone
- +52 868 402 5820
- Website
- facebook.com
Taxi Medellín
- Phone
- +52 868 903 6513
- Website
- facebook.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide





