There are 8 ways to get from Santa Isabel to Cuenca, Ecuador by plane, bus, car, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Cuenca
best- Fly from São Paulo–Guarulhos International Airport (GRU) to Cuenca (CUE)plane GRU - CUE
15h 42m$226–717Bus
- Take the bus from Avenida Coronel Bertoldo, 320 to R. Voluntários da Pátria, 560 - sala 104 - Santana, São Paulo - SP, 02010-000, Brasilbus
- Take the bus from Tietê Bus Terminal to Icabus
- Take the bus from Ica to Limabus
- Take the bus from Lima to Chiclayobus
- Take the bus from Chiclayo to Cuencabus
5d 11h$326–723Drive 5,803.6 km
- Drive from Santa Isabel to Cuenca, Ecuadorcar 5,803.6 km
3d 7h$585–845Fly to José Joaquín De Olmedo International Airport, taxi
- Fly from São Paulo–Guarulhos International Airport (GRU) to José Joaquín De Olmedo International Airport (GYE)plane GRU - GYE
- Take the taxi from Guayaquil-Airport-GYE to Cuenca, Ecuadortaxi
16h 6m$376–577Fly to Tumbes, bus
- Fly from São Paulo–Guarulhos International Airport (GRU) to Tumbes (TBP)plane GRU - TBP
- Take the bus from Huaquillas to Cuencabus
19h$277–791Bus via Santiago
- Take the bus from Tietê Bus Terminal to Terminal San Borjabus
- Take the bus from Terminal San Borja to Terminal Terrestre Quitumbebus
- Take the bus from Terminal Terrestre Quitumbe to Terminal Terrestre de Ambatobus
- Take the bus from Ambato to Cuencabus
5d 15h$519–796Bus #2
- Take the bus from Rua Maria Isabel, 276 to Rua Guaporé, 117 - Ponto Final das Linhas 219 e 820 - Luz, São Paulo - SP, 01109-030, Brasilbus
- Take the bus from Tietê Bus Terminal to Lima - Atocongobus
- Take the bus from Gran Terminal Terrestre Plaza Norte to Piurabus
- Take the bus from Terminal de Piura to Terminal de Cuencabus
5d 20h$341–784Bus #3
- Take the bus from Rua Maria Isabel, 276 to Rua Guaporé, 117 - Ponto Final das Linhas 219 e 820 - Luz, São Paulo - SP, 01109-030, Brasilbus
- Take the bus from Tietê Bus Terminal to Lima - Atocongobus
- Take the bus from Gran Terminal Terrestre Plaza Norte to Terminal Terrestre de Guayaquilbus
- Take the bus from Terminal Terrestre de Guayaquil to Cuencabus
6d 4h$387–857
São Paulo–Guarulhos International Airport (GRU) to Cuenca (CUE) flights
Comparing Your Travel Options
The cheapest way to get from Santa Isabel to Cuenca, Ecuador is to bus which costs $320 - $750 and takes 5 days 11h.
The fastest way to get from Santa Isabel to Cuenca, Ecuador is to fly which takes 15h 42m and costs $220 - $750.
No, there is no direct bus from Santa Isabel to Cuenca, Ecuador. However, there are services departing from Avenida Coronel Bertoldo, 320 and arriving at Cuenca via Tietê Bus Terminal, Ica, Lima and Chiclayo. The journey, including transfers, takes approximately 5 days 11h.
The distance between Santa Isabel and Cuenca, Ecuador is 4258 km. The road distance is 5803.6 km.
The best way to get from Santa Isabel to Cuenca, Ecuador without a car is to bus which takes 5 days 11h and costs $320 - $750.
It takes approximately 15h 42m to get from Santa Isabel to Cuenca, Ecuador, including transfers.
Santa Isabel to Cuenca, Ecuador bus services, operated by EMTU, depart from Avenida Coronel Bertoldo, 320 station.
The best way to get from Santa Isabel to Cuenca, Ecuador is to fly which takes 15h 42m and costs $220 - $750. Alternatively, you can bus, which costs $320 - $750 and takes 5 days 11h.
Santa Isabel to Cuenca, Ecuador bus services, operated by EMTU, arrive at R. Voluntários da Pátria, 560 - sala 104 - Santana, São Paulo - SP, 02010-000, Brasil station.
Cuenca, Ecuador is 2h behind Santa Isabel. It is currently 9:58 PM in Santa Isabel and 7:58 PM in Cuenca, Ecuador.
What companies run services between Santa Isabel, Brazil and Cuenca, Ecuador?
LATAM Chile and Avianca - Aerovías del Continente Americano S.A. fly from São Paulo–Guarulhos International Airport (GRU) to Cuenca (CUE) 3 times a day. Alternatively, you can take a bus from Avenida Coronel Bertoldo, 320 to Cuenca via R. Voluntários da Pátria, 560 - sala 104 - Santana, São Paulo - SP, 02010-000, Brasil, Tietê Bus Terminal, Ica, Lima, Lima, and Chiclayo in around 5d 11h.
- Website
- latam.com
Flights from São Paulo–Guarulhos International Airport to Cuenca via Lima, Quito
- Ave. Duration
- 12h 5m
- When
- Monday, Tuesday, Wednesday, Thursday, and Saturday
- Estimated price
- $240–750
Flights from São Paulo–Guarulhos International Airport to Cuenca via Lima, José Joaquín De Olmedo International Airport
- Ave. Duration
- 14h 13m
- When
- Friday
- Estimated price
- $220–700
Flights from São Paulo–Guarulhos International Airport to Cuenca via Bogota, Quito
- Ave. Duration
- 18h 17m
- When
- Thursday and Saturday
- Estimated price
- $240–750
Flights from São Paulo–Guarulhos International Airport to Cuenca via Santiago, Quito
- Ave. Duration
- 20h 15m
- When
- Tuesday
- Estimated price
- $290–850
Flights from São Paulo–Guarulhos International Airport to José Joaquín De Olmedo International Airport via Lima
- Ave. Duration
- 8h 32m
- When
- Every day
- Estimated price
- $260–380
Flights from São Paulo–Guarulhos International Airport to José Joaquín De Olmedo International Airport via Santiago
- Ave. Duration
- 10h 58m
- When
- Every day
- Estimated price
- $260–380
Flights from São Paulo–Guarulhos International Airport to Tumbes via Lima
- Ave. Duration
- 9h 50m
- When
- Every day
- Estimated price
- $300–950
Flights from São Paulo–Guarulhos International Airport to Tumbes via Cuzco, Lima
- Ave. Duration
- 9h 35m
- When
- Sunday
- Estimated price
- $300–950
Flights from São Paulo–Guarulhos International Airport to Tumbes via Asuncion, Lima
- Ave. Duration
- 16h 35m
- When
- Wednesday
- Estimated price
- $310–950
Flights from São Paulo–Guarulhos International Airport to Tumbes via Rio De Janeiro-Galeao, Lima
- Ave. Duration
- 18h
- When
- Saturday
- Estimated price
- $330–1,000
- Website
- avianca.com
Flights from São Paulo–Guarulhos International Airport to Cuenca via Bogota, Quito
- Ave. Duration
- 14h 52m
- When
- Monday, Tuesday, Wednesday, Friday, and Sunday
- Estimated price
- $290–950
Flights from São Paulo–Guarulhos International Airport to José Joaquín De Olmedo International Airport via Bogota
- Ave. Duration
- 9h 17m
- When
- Every day
- Estimated price
- $330–1,100
- Website
- copaair.com
Flights from São Paulo–Guarulhos International Airport to José Joaquín De Olmedo International Airport via Panama City
- Ave. Duration
- 10h 43m
- When
- Every day
- Estimated price
- $210–850
- Website
- skyairline.com
Flights from São Paulo–Guarulhos International Airport to Tumbes via Lima
- Ave. Duration
- 18h 10m
- When
- Wednesday and Saturday
- Estimated price
- $260–750
Bus from Avenida Coronel Bertoldo, 320 to R. Voluntários da Pátria, 560 - sala 104 - Santana, São Paulo - SP, 02010-000, Brasil
- Ave. Duration
- 53 min
- Frequency
- 4 times a day
- Estimated price
- $1–3
- Schedules at
- emtu.sp.gov.br
- Commuter bus
- $1–2
Bus from Rua Maria Isabel, 276 to Rua Guaporé, 117 - Ponto Final das Linhas 219 e 820 - Luz, São Paulo - SP, 01109-030, Brasil
- Ave. Duration
- 1h 38m
- Frequency
- Hourly
- Estimated price
- $1–3
- Schedules at
- emtu.sp.gov.br
- Commuter bus
- $1–2
Bus from Rua Maria Isabel, 276 to Rua Guaporé, 117 - Ponto Final das Linhas 219 e 820 - Luz, São Paulo - SP, 01109-030, Brasil
- Ave. Duration
- 1h 38m
- Frequency
- Hourly
- Estimated price
- $1–3
- Schedules at
- emtu.sp.gov.br
- Commuter bus
- $1–2
- Phone
- +55 (68) 3221-1660
- Website
- transacreana.com.br
Bus from Tietê Bus Terminal to Ica
- Ave. Duration
- 4d 6h
- Frequency
- Once a week
- Estimated price
- $250–600
- Schedules at
- transacreana.com.br
- Book at
- transacreana.com.br
Bus from Tietê Bus Terminal to Lima - Atocongo
- Ave. Duration
- 4d 16h
- Frequency
- Once a week
- Estimated price
- $250–650
- Schedules at
- transacreana.com.br
- Book at
- transacreana.com.br
Bus from Tietê Bus Terminal to Lima - Atocongo
- Ave. Duration
- 4d 16h
- Frequency
- Once a week
- Estimated price
- $250–650
- Schedules at
- transacreana.com.br
- Book at
- transacreana.com.br
- Phone
- +51 1 4800725
- [email protected]
- Website
- floreshnos.pe
Bus from Ica to Lima
- Ave. Duration
- 4h
- Frequency
- Hourly
- Estimated price
- $13–26
- Schedules at
- floreshnos.pe
- Book at
- floreshnos.pe
- Phone
- +51 979 707 957
- [email protected]
- Website
- terramovilperu.com.pe
Bus from Lima to Chiclayo
- Ave. Duration
- 10h 30m
- Frequency
- Hourly
- Estimated price
- $35
- Schedules at
- terramovilperu.com.pe
- Book at
- redbus.pe
- Phone
- +593-07 2823163
- [email protected]
- Website
- transportesazuay.com
Bus from Chiclayo to Cuenca
- Ave. Duration
- 10h
- Frequency
- Once daily
- Estimated price
- $27–60
- Schedules at
- transportesazuay.com
Bus from Huaquillas to Cuenca
- Ave. Duration
- 4h
- Frequency
- Hourly
- Estimated price
- $8–19
- Schedules at
- transportesazuay.com
- Phone
- +55 51 3475.4440
- [email protected]
- Website
- jblinternacional.com
Bus from Tietê Bus Terminal to Terminal San Borja
- Ave. Duration
- 2d 7h
- Frequency
- Once a week
- Estimated price
- $180–300
- Schedules at
- jblinternacional.com
- Book at
- jblinternacional.com
- Phone
- +51 9 6788 4526
- [email protected]
- Website
- Lineas De Los Andes
Bus from Terminal San Borja to Terminal Terrestre Quitumbe
- Ave. Duration
- 2d 21h
- Frequency
- Once daily
- Estimated price
- $320–460
- Website
- Lineas De Los Andes
Bus from Gran Terminal Terrestre Plaza Norte to Terminal Terrestre de Guayaquil
- Ave. Duration
- 27h
- Frequency
- Once daily
- Estimated price
- $100–130
- Website
- Lineas De Los Andes
- Phone
- +593 99 7670616
- [email protected]
- Website
- Flota Pelileo
Bus from Terminal Terrestre Quitumbe to Terminal Terrestre de Ambato
- Ave. Duration
- 2h 55m
- Frequency
- Hourly
- Estimated price
- $6–9
- Schedules at
- Flota Pelileo
- Phone
- +593 98 076 1302
- [email protected]
- Website
- cooperativabanos.com
Bus from Terminal Terrestre Quitumbe to Terminal Terrestre de Ambato
- Ave. Duration
- 2h 35m
- Frequency
- Every 2 hours
- Estimated price
- $4–14
- Schedules at
- facebook.com
Bus from Terminal Terrestre Quitumbe to Terminal Terrestre de Ambato
- Ave. Duration
- 2h 35m
- Frequency
- Once daily
- Estimated price
- $7–12
- Schedules at
- BAÑOS Cooperativa De Transportes y Turismo
- Phone
- +593 3 252 1073
- [email protected]
- Website
- cooperativasanta.ec
Bus from Ambato to Cuenca
- Ave. Duration
- 3h 29m
- Frequency
- Every 4 hours
- Estimated price
- $10–15
- Schedules at
- cooperativasanta.ec
- Phone
- +51 511 418 1111
- [email protected]
- Website
- CIVA
Bus from Gran Terminal Terrestre Plaza Norte to Piura
- Ave. Duration
- 13h 45m
- Frequency
- Hourly
- Estimated price
- $35–55
- Schedules at
- CIVA
- Phone
- +51 993 558 525
- [email protected]
- Website
- turismocavassa.com.pe
Bus from Gran Terminal Terrestre Plaza Norte to Piura
- Ave. Duration
- 16h 30m
- Frequency
- 5 times a day
- Estimated price
- $27–40
- Schedules at
- turismocavassa.com.pe
- Phone
- +593 98 453 6454
- [email protected]
- Website
- facebook.com
Bus from Terminal de Piura to Terminal de Cuenca
- Ave. Duration
- 9h
- Frequency
- Once daily
- Estimated price
- $34–37
- Book at
- redbus.pe
Bus from Terminal Terrestre de Guayaquil to Cuenca
- Ave. Duration
- 4h 15m
- Frequency
- Every 4 hours
- Estimated price
- $11–35
- Book at
- redbus.pe
- Phone
- +593 99 144 1474
- [email protected]
- Website
- facebook.com
Bus from Terminal Terrestre de Guayaquil to Cuenca
- Ave. Duration
- 3h 30m
- Frequency
- Hourly
- Estimated price
- $8–11
- Schedules at
- facebook.com
- Book at
- ecuabuses.com
- Phone
- +593 09 9900 8843
- [email protected]
Bus from Terminal Terrestre de Guayaquil to Cuenca
- Ave. Duration
- 3h 35m
- Frequency
- 5 times a day
- Estimated price
- $7–10
- Schedules at
- facebook.com
- Ave. Duration
- 3h 4m
- Estimated price
- $110–140
Aeropuerto g y e taxis
- Phone
- +593 96 015 5142
- Website
- facebook.com
Auto Amigo
- Phone
- +593 99 317 1528
- Website
- facebook.com
Ivan Car
- Phone
- +593 0 4371 1800
- Website
- ivancar-ec.com
Want to know more about travelling around the world?
Rome2Rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including Travelling by boat in Italy, Best ways to travel around Australia, and 10 amazing places to get away from it all in Australia - to help you get the most out of your next trip.
Booking & Getting There
Yes, the driving distance between Santa Isabel to Cuenca, Ecuador is 5804 km. It takes approximately 3 days 7h to drive from Santa Isabel to Cuenca, Ecuador.
There are 455+ hotels available in Cuenca, Ecuador.









































