There are 5 ways to get from Santa Maria to Milpitas by bus (Amtrak), bus, train, car, plane, or subway
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Santa Maria Transit Center to Government Centerbus 10N
- Take the bus from San Luis Obispo to San Josebus Amtrak Thruway Connecting Service
8h 16m$68–107Drive 218.2 mi
cheapest- Drive from Santa Maria to Milpitascar 218.2 mi
3h 56m$40–58Bus, train
- Take the bus from Santa Maria Transit Center to Government Centerbus 10N
- Take the train from San Luis Obispo to San Josetrain Coast Starlight
8h 42m$67–148Bus to San Luis Obispo County Regional Airport, fly, BART
- Take the bus from Santa Maria Transit Center to Government Centerbus
- Fly from San Luis Obispo County Regional Airport (SBP) to San Francisco International Airport (SFO)plane SBP - SFO
- Take the subway from Daly City to Milpitassubway
6h 26m$182–419Bus to Santa Barbara Municipal Airport, fly, BART
- Take the bus from Santa Maria Airport, CA to Santa Barbara Airportbus
- Fly from Santa Barbara Municipal Airport (SBA) to San Francisco International Airport (SFO)plane SBA - SFO
- Take the subway from Daly City to Milpitassubway
6h 32m$259–531
San Luis Obispo County Regional Airport (SBP) to San Francisco International Airport (SFO) flights
Questions & Answers
The cheapest way to get from Santa Maria to Milpitas is to drive which costs $40 - $60 and takes 3h 56m.
The fastest way to get from Santa Maria to Milpitas is to drive which takes 3h 56m and costs $40 - $60.
No, there is no direct bus from Santa Maria to Milpitas. However, there are services departing from Santa Maria Transit Center and arriving at Main & Serra via Downtown Transit Center, San Luis Obispo, San Jose Diridon and 1st & Santa Clara. The journey, including transfers, takes approximately 8h 16m.
The distance between Santa Maria and Milpitas is 237 miles. The road distance is 219.4 miles.
The best way to get from Santa Maria to Milpitas without a car is to bus which takes 8h 16m and costs $65 - $110.
It takes approximately 8h 16m to get from Santa Maria to Milpitas, including transfers.
Santa Maria to Milpitas bus services, operated by San Luis Obispo RTA, depart from Santa Maria Transit Center station.
Santa Maria to Milpitas bus services, operated by San Luis Obispo RTA, arrive at Government Center station.
Yes, the driving distance between Santa Maria to Milpitas is 219 miles. It takes approximately 3h 56m to drive from Santa Maria to Milpitas.
There are 489+ hotels available in Milpitas.
What companies run services between Santa Maria, Santa Barbara County, CA, USA and Milpitas, CA, USA?
You can take a bus from Santa Maria Transit Center to Main & Serra via Government Center, Downtown Transit Center, Santa Barbara at Church, San Luis Obispo, San Jose, San Jose Diridon, Santa Clara & 2nd, and 1st & Santa Clara in around 8h 16m.
- Website
- united.com
Flights from San Luis Obispo County Regional Airport to San Francisco International Airport
- Ave. Duration
- 1h 7m
- When
- Every day
- Estimated price
- $21–150
Flights from Santa Barbara Municipal Airport to San Francisco International Airport
- Ave. Duration
- 1h 18m
- When
- Every day
- Estimated price
- $23–160
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from San Luis Obispo to San Jose
- Ave. Duration
- 4h 41m
- Frequency
- Once daily
- Estimated price
- $60–140
- Website
- Amtrak
- Phone
- +1-510-464-6000
- Website
- BART
Subway from Daly City to Milpitas
- Ave. Duration
- 1h 18m
- Frequency
- Every 30 minutes
- Estimated price
- $9–12
- Website
- BART
Subway from Daly City to Milpitas
- Ave. Duration
- 1h 18m
- Frequency
- Every 30 minutes
- Estimated price
- $9–12
- Website
- BART
- Website
- SoCoTransit
Bus from Santa Maria Transit Center to Government Center
- Ave. Duration
- 1h 18m
- Frequency
- Every 2 hours
- Estimated price
- $2–4
- Website
- SoCoTransit
Bus from Santa Maria Transit Center to Government Center
- Ave. Duration
- 1h 18m
- Frequency
- Every 2 hours
- Estimated price
- $2–4
- Website
- SoCoTransit
Bus from Santa Maria Transit Center to Government Center
- Ave. Duration
- 1h 18m
- Frequency
- Every 2 hours
- Estimated price
- $2–4
- Website
- SoCoTransit
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from San Luis Obispo to San Jose
- Ave. Duration
- 4h
- Frequency
- 4 times a day
- Estimated price
- $60–90
- Website
- Amtrak
- Phone
- +1 800-470-8818
- [email protected]
- Website
- Central Coast Shuttle
Bus from Santa Maria Airport, CA to Santa Barbara Airport
- Ave. Duration
- 1h 13m
- Frequency
- Every 4 hours
- Estimated price
- $60–75
- Website
- Central Coast Shuttle
- one way non-prepaid
- $65–75
- One-way prepaid 48 hours advance
- $60–70
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide








