There are 9 ways to get from Santa Maria di Leuca to Assisi by bus, train, train (Trenitalia), car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, train
best- Take the bus from Santa Maria di Leuca - Piazzale Le Terrazze to Lecce - Viale Gallipolibus 108 / ...
- Take the train from Lecce to Pescara Centraletrain Fr
- Take the bus from Pescara to Assisibus 443
13h 41m€71–154Bus
cheapest- Take the bus from Santa Maria di Leuca - Piazzale Le Terrazze to Lecce - City Terminalbus 108 / ...
- Take the bus from Lecce Central Bus Station to Perugia Train Station Bus Stopbus Itabus
17h 35m€47–94Train
- Take the train from Gagliano Leuca to Leccetrain 6
- Take the train from Lecce to Anconatrain Fr
- Take the train from Ancona to Folignotrain Re
14h 33m€85–182Drive 753.2 km
- Drive from Santa Maria di Leuca to Assisicar 753.2 km
7h 47m€137–197Bus to Brindisi Airport, fly to Fiumicino International Airport, train
- Take the bus from Santa Maria di Leuca - Piazzale Le Terrazze to Lecce - Viale Gallipolibus
- Fly from Brindisi Airport (BDS) to Fiumicino International Airport (FCO)plane BDS - FCO
- Take the train from Roma Termini to Assisitrain
10h 44m€61–240Bus via Rome
- Take the bus from Santa Maria di Leuca - Piazzale Le Terrazze to Lecce - City Terminalbus 108 / ...
- Take the bus from Lecce to Roma, Autostazione Tiburtinabus 570 / ...
- Take the bus from Roma, Autostazione Tiburtina to Assisi - Piazza San Pietrobus
15h 11m€77–112Bus, train to Bari Karol Wojtyła Airport, fly to Fiumicino International Airport, train
- Take the bus from Santa Maria di Leuca - Piazzale Le Terrazze to Lecce - Viale Gallipolibus
- Take the train from Lecce to Bari Centraletrain
- Fly from Bari Karol Wojtyła Airport (BRI) to Fiumicino International Airport (FCO)plane BRI - FCO
- Take the train from Roma Termini to Assisitrain
11h 46m€73–231Bus to Brindisi Airport, fly to Bologna Guglielmo Marconi Airport, train
- Take the bus from Santa Maria di Leuca - Piazzale Le Terrazze to Lecce - Viale Gallipolibus
- Fly from Brindisi Airport (BDS) to Bologna Guglielmo Marconi Airport (BLQ)plane BDS - BLQ
- Take the train from Bologna Centrale to Assisitrain
11h 49m€84–244Bus to Brindisi Airport, fly to Pisa International Airport, train
- Take the bus from Santa Maria di Leuca - Piazzale Le Terrazze to Lecce - Viale Gallipolibus
- Fly from Brindisi Airport (BDS) to Pisa International Airport (PSA)plane BDS - PSA
- Take the train from Pisa Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Assisitrain
12h 38m€98–294
Santa Maria di Leuca to Assisi by bus, foot, and train
Comparing Your Travel Options
The cheapest way to get from Santa Maria di Leuca to Assisi is to bus which costs €45 - €95 and takes 17h 35m.
The fastest way to get from Santa Maria di Leuca to Assisi is to drive which takes 7h 47m and costs €130 - €200.
No, there is no direct bus from Santa Maria di Leuca to Assisi. However, there are services departing from Santa Maria di Leuca - Piazzale Le Terrazze and arriving at Assisi - Piazza San Pietro via Lecce and Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 15h 11m.
No, there is no direct train from Santa Maria di Leuca to Assisi. However, there are services departing from Gagliano Leuca and arriving at Assisi via Lecce, Ancona and Foligno. The journey, including transfers, takes approximately 14h 33m.
The distance between Santa Maria di Leuca and Assisi is 780 km. The road distance is 753.2 km.
The best way to get from Santa Maria di Leuca to Assisi without a car is to bus and train which takes 13h 41m and costs €70 - €160.
It takes approximately 13h 41m to get from Santa Maria di Leuca to Assisi, including transfers.
Santa Maria di Leuca to Assisi bus services, operated by Salento in bus, depart from Santa Maria di Leuca - Piazzale Le Terrazze station.
Santa Maria di Leuca to Assisi train services, operated by Ferrovie del Sud Est e Servizi Automobilistici S.r.l., depart from Gagliano Leuca station.
The best way to get from Santa Maria di Leuca to Assisi is to train which takes 14h 33m and costs €80 - €190. Alternatively, you can bus via Rome, which costs €75 - €120 and takes 15h 11m.
What companies run services between Santa Maria di Leuca, Italy and Assisi, Italy?
You can take a bus from Santa Maria di Leuca to Via San Francesco via Gagliano del Capo FS, Gagliano Leuca, Lecce, Ancona, Foligno, Assisi, and Assisi Stazione in around 14h 33m. Alternatively, you can take a bus from Santa Maria di Leuca - Piazzale Le Terrazze to Assisi - Piazza San Pietro via Lecce and Roma, Autostazione Tiburtina in around 15h 11m.
- Website
- ryanair.com
Flights from Brindisi Airport to Fiumicino International Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €28–160
Flights from Bari Karol Wojtyła Airport to Fiumicino International Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €24–120
Flights from Brindisi Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €40–150
Flights from Brindisi Airport to Pisa International Airport
- Ave. Duration
- 1h 25m
- When
- Monday, Thursday, Sunday, Saturday, and Friday
- Estimated price
- €50–200
- Website
- ita-airways.com
Flights from Brindisi Airport to Fiumicino International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €55–180
Flights from Bari Karol Wojtyła Airport to Fiumicino International Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €55–150
- Website
- neosair.it
Flights from Bari Karol Wojtyła Airport to Fiumicino International Airport
- Ave. Duration
- 1h
- When
- Sunday
- Estimated price
- €110–340
- Website
- skyalps.com
Flights from Bari Karol Wojtyła Airport to Fiumicino International Airport via Mostar
- Ave. Duration
- 2h 55m
- When
- Monday and Friday
- Estimated price
- €130–310
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Lecce to Pescara Centrale
- Ave. Duration
- 4h 3m
- Frequency
- 5 times a day
- Estimated price
- €60–110
- Website
- Trenitalia Frecce
Train from Lecce to Ancona
- Ave. Duration
- 5h 18m
- Frequency
- 5 times a day
- Estimated price
- €80–140
- Website
- Trenitalia Frecce
Train from Lecce to Bari Centrale
- Ave. Duration
- 1h 24m
- Frequency
- Every 3 hours
- Estimated price
- €20–35
- Website
- Trenitalia Frecce
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Lecce to Pescara Centrale
- Ave. Duration
- 4h 37m
- Frequency
- 5 times a day
- Estimated price
- €45–90
- Website
- Trenitalia Intercity
Train from Lecce to Ancona
- Ave. Duration
- 6h 12m
- Frequency
- 5 times a day
- Estimated price
- €65–120
- Website
- Trenitalia Intercity
Train from Ancona to Foligno
- Ave. Duration
- 2h 1m
- Frequency
- Twice daily
- Estimated price
- €14–25
- Website
- Trenitalia Intercity
Train from Roma Termini to Assisi
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- €18–35
- Website
- Trenitalia Intercity
Train from Lecce to Bari Centrale
- Ave. Duration
- 3h 1m
- Frequency
- 5 times a day
- Estimated price
- €16–29
- Website
- Trenitalia Intercity
Train from Roma Termini to Assisi
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- €18–35
- Website
- Trenitalia Intercity
Train from Bologna Centrale to Assisi
- Ave. Duration
- 3h 31m
- Frequency
- Once daily
- Estimated price
- €29–55
- Website
- Trenitalia Intercity
Train from Firenze S.M.N. to Assisi
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Estimated price
- €19–35
- Website
- Trenitalia Intercity
- Phone
- 800 07 9090
- Website
- fssudest.it
Train from Gagliano Leuca to Lecce
- Ave. Duration
- 2h 16m
- Frequency
- Every 3 hours
- Estimated price
- €3–10
- Schedules at
- fssudest.it
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Ancona to Foligno
- Ave. Duration
- 1h 47m
- Frequency
- Every 3 hours
- Estimated price
- €15–21
- Website
- Trenitalia
Train from Roma Termini to Assisi
- Ave. Duration
- 2h 6m
- Frequency
- 5 times a day
- Estimated price
- €19–27
- Website
- Trenitalia
Train from Lecce to Bari Centrale
- Ave. Duration
- 1h 54m
- Frequency
- Hourly
- Estimated price
- €17–25
- Website
- Trenitalia
Train from Roma Termini to Assisi
- Ave. Duration
- 2h 6m
- Frequency
- 5 times a day
- Estimated price
- €19–27
- Website
- Trenitalia
Train from Pisa Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 22m
- Frequency
- Every 30 minutes
- Estimated price
- €9–13
- Website
- Trenitalia
Train from Firenze S.M.N. to Assisi
- Ave. Duration
- 2h 46m
- Frequency
- Every 4 hours
- Estimated price
- €20–29
- Website
- Trenitalia
- Phone
- +39 800 242 815, 344/2274620
- [email protected]
- Website
- provincia.le.it
Bus from Santa Maria di Leuca - Piazzale Le Terrazze to Lecce - Viale Gallipoli
- Ave. Duration
- 2h 15m
- Frequency
- Hourly
- Estimated price
- €4–7
- Schedules at
- provincia.le.it
Bus from Santa Maria di Leuca - Piazzale Le Terrazze to Lecce - Viale Gallipoli
- Ave. Duration
- 2h 15m
- Frequency
- Hourly
- Estimated price
- €4–7
- Schedules at
- provincia.le.it
Bus from Santa Maria di Leuca - Piazzale Le Terrazze to Lecce - City Terminal
- Ave. Duration
- 2h 25m
- Frequency
- Hourly
- Estimated price
- €4–7
- Schedules at
- provincia.le.it
Bus from Santa Maria di Leuca - Piazzale Le Terrazze to Lecce - City Terminal
- Ave. Duration
- 2h 25m
- Frequency
- Hourly
- Estimated price
- €4–7
- Schedules at
- provincia.le.it
Bus from Santa Maria di Leuca - Piazzale Le Terrazze to Lecce - Viale Gallipoli
- Ave. Duration
- 2h 15m
- Frequency
- Hourly
- Estimated price
- €4–7
- Schedules at
- provincia.le.it
Bus from Santa Maria di Leuca - Piazzale Le Terrazze to Lecce - Viale Gallipoli
- Ave. Duration
- 2h 15m
- Frequency
- Hourly
- Estimated price
- €4–7
- Schedules at
- provincia.le.it
Bus from Santa Maria di Leuca - Piazzale Le Terrazze to Lecce - Viale Gallipoli
- Ave. Duration
- 2h 15m
- Frequency
- Hourly
- Estimated price
- €4–7
- Schedules at
- provincia.le.it
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Pescara to Assisi
- Ave. Duration
- 4h 5m
- Frequency
- 3 times a day
- Estimated price
- €21–35
- Website
- Flixbus
Bus from Lecce to Roma, Autostazione Tiburtina
- Ave. Duration
- 8h 15m
- Frequency
- Hourly
- Estimated price
- €50–80
- Website
- Flixbus
- Phone
- +39 075 5009641
- [email protected]
- Website
- sulga.it
Bus from Roma, Autostazione Tiburtina to Assisi - Piazza San Pietro
- Ave. Duration
- 2h 45m
- Frequency
- 6 times a week
- Estimated price
- €23–26
- Schedules at
- sulga.it
- 2nd Class
- €23–26
- Phone
- +39 06 88 93 82 32
- Website
- Itabus S.p.A.
Bus from Lecce Central Bus Station to Perugia Train Station Bus Stop
- Ave. Duration
- 12h
- Frequency
- Twice daily
- Estimated price
- €40–80
- Website
- Itabus S.p.A.
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Booking & Getting There
Santa Maria di Leuca to Assisi bus services, operated by Salento in bus, arrive at Lecce - City Terminal station.
Santa Maria di Leuca to Assisi train services, operated by Ferrovie del Sud Est e Servizi Automobilistici S.r.l., arrive at Lecce station.
Yes, the driving distance between Santa Maria di Leuca to Assisi is 753 km. It takes approximately 7h 47m to drive from Santa Maria di Leuca to Assisi.
There are 2348+ hotels available in Assisi.





























