There are 7 ways to get from Santa Monica to Florida Keys by plane, train, bus, car, shuttle, or ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Key West International Airport
best- Fly from Los Angeles International Airport (LAX) to Key West International Airport (EYW)plane LAX - EYW
11h 48m$173–497Train, bus
- Take the train from Los Angeles to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Miami Amtrak Stationtrain
- Take the bus from Miami Airport Station to Big Pine Keybus
4d 3h$2,347–3,767Drive 2,830.6 mi
- Drive from Santa Monica to Florida Keyscar 2,830.6 mi
47h 15m$517–747Fly to Miami International Airport, shuttle
- Fly from Los Angeles International Airport (LAX) to Miami International Airport (MIA)plane LAX - MIA
- Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FL
12h 24m$343–837Fly to Fort Lauderdale–Hollywood International Airport, shuttle
- Fly from Los Angeles International Airport (LAX) to Fort Lauderdale–Hollywood International Airport (FLL)plane LAX - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
12h 52m$513–1,207Fly to Ft. Myers, ferry
- Fly from Los Angeles International Airport (LAX) to Ft. Myers (RSW)plane LAX - RSW
- Take the ferry from Fort Myers Beach, FL to Key West, FLferry
15h 32m$307–783Bus, train
- Take the bus from Los Angeles Union Station to Ft Worth Bus Stationbus
- Take the train from Fort Worth to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Miami Amtrak Stationtrain
- Take the bus from Miami Airport Station to Big Pine Keybus
4d 13h$1,945–3,145
Santa Monica to Florida Keys by tram, subway, train, taxi, bus, and foot
Comparing Your Travel Options
The cheapest way to get from Santa Monica to Florida Keys is to fly which costs $170 - $500 and takes 11h 48m.
The fastest way to get from Santa Monica to Florida Keys is to fly which takes 11h 48m and costs $170 - $500.
The distance between Santa Monica and Florida Keys is 2336 miles. The road distance is 2847.1 miles.
The best way to get from Santa Monica to Florida Keys without a car is to train and bus which takes 4 days 3h and costs $2,300 - $3,800.
It takes approximately 11h 48m to get from Santa Monica to Florida Keys, including transfers.
Yes, the driving distance between Santa Monica to Florida Keys is 2847 miles. It takes approximately 47h 15m to drive from Santa Monica to Florida Keys.
There are 964+ hotels available in Florida Keys.
What companies run services between Santa Monica, CA, USA and Florida Keys, FL, USA?
American Airlines and Delta fly from Los Angeles International Airport (LAX) to Key West International Airport (EYW) every 4 hours.
- Website
- aa.com
Flights from Los Angeles International Airport to Key West International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 54m
- When
- Every day
- Estimated price
- $95–400
Flights from Los Angeles International Airport to Key West International Airport via Miami International Airport
- Ave. Duration
- 7h 14m
- When
- Every day
- Estimated price
- $100–420
Flights from Los Angeles International Airport to Miami International Airport
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- $110–470
Flights from Los Angeles International Airport to Ft. Myers via Dallas/Ft.Worth
- Ave. Duration
- 7h 22m
- When
- Every day
- Estimated price
- $140–600
- Website
- southwest.com
Flights from Los Angeles International Airport to Miami International Airport via Houston Hobby Apt
- Ave. Duration
- 6h 20m
- When
- Monday and Sunday
- Estimated price
- $110–470
Flights from Los Angeles International Airport to Miami International Airport via Austin
- Ave. Duration
- 6h 35m
- When
- Tuesday and Wednesday
- Estimated price
- $110–470
Flights from Los Angeles International Airport to Miami International Airport via Dallas
- Ave. Duration
- 6h 50m
- When
- Tuesday
- Estimated price
- $110–470
Flights from Los Angeles International Airport to Fort Lauderdale–Hollywood International Airport via Houston Hobby Apt
- Ave. Duration
- 6h 25m
- When
- Monday, Sunday, Tuesday, and Wednesday
- Estimated price
- $130–550
Flights from Los Angeles International Airport to Fort Lauderdale–Hollywood International Airport via New Orleans
- Ave. Duration
- 6h 42m
- When
- Monday, Thursday, and Friday
- Estimated price
- $130–550
Flights from Los Angeles International Airport to Fort Lauderdale–Hollywood International Airport via Austin
- Ave. Duration
- 6h 25m
- When
- Tuesday
- Estimated price
- $130–550
Flights from Los Angeles International Airport to Ft. Myers via Dallas
- Ave. Duration
- 8h 40m
- When
- Saturday
- Estimated price
- $140–600
- Website
- delta.com
Flights from Los Angeles International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 7h 56m
- When
- Every day
- Estimated price
- $100–430
Flights from Los Angeles International Airport to Miami International Airport
- Ave. Duration
- 5h 2m
- When
- Every day
- Estimated price
- $110–470
Flights from Los Angeles International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 4h 53m
- When
- Every day
- Estimated price
- $130–550
- Website
- jetblue.com
Flights from Los Angeles International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- $130–550
- Website
- united.com
Flights from Los Angeles International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 5h 15m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $130–550
Flights from Los Angeles International Airport to Fort Lauderdale–Hollywood International Airport via Houston
- Ave. Duration
- 6h 55m
- When
- Every day
- Estimated price
- $130–550
Flights from Los Angeles International Airport to Ft. Myers
- Ave. Duration
- 4h 56m
- When
- Saturday
- Estimated price
- $140–600
Flights from Los Angeles International Airport to Ft. Myers via Houston
- Ave. Duration
- 6h 52m
- When
- Every day
- Estimated price
- $140–600
- Website
- flybreeze.com
Flights from Los Angeles International Airport to Ft. Myers via New Orleans
- Ave. Duration
- 9h 35m
- When
- Tuesday and Friday
- Estimated price
- $180–950
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Los Angeles to Chicago Union Station
- Ave. Duration
- 43h 23m
- Frequency
- Once daily
- Estimated price
- $1,200–1,900
- Website
- Amtrak
Train from Chicago Union Station to Miami Amtrak Station
- Ave. Duration
- 46h 29m
- Frequency
- Once daily
- Estimated price
- $1,100–1,800
- Website
- Amtrak
Train from Fort Worth to Chicago Union Station
- Ave. Duration
- 23h 26m
- Frequency
- Once daily
- Estimated price
- $550–900
- Website
- Amtrak
Train from Chicago Union Station to Miami Amtrak Station
- Ave. Duration
- 46h 29m
- Frequency
- Once daily
- Estimated price
- $1,100–1,800
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $22–35
- Website
- Greyhound
Bus from Los Angeles Union Station to Ft Worth Bus Station
- Ave. Duration
- 28h 20m
- Frequency
- Twice daily
- Estimated price
- $250–380
- Website
- Greyhound
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $22–35
- Website
- Greyhound
- Phone
- +1 (305) 289-9997
- [email protected]
- Website
- Keys Shuttle
Shuttle from Miami, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h
- Frequency
- 3 times a day
- Estimated price
- $150–180
- Website
- Keys Shuttle
Shuttle from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $170–200
- Website
- Keys Shuttle
- Phone
- +1 239-463-5733
- Website
- Key West Express
Ferry from Fort Myers Beach, FL to Key West, FL
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $130
- Website
- Key West Express
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