There are 6 ways to get from Santa Rosa to Greenville by plane, bus (Greyhound), bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Sonoma County Airport
best- Fly from Sonoma County Airport (STS) to Greenville–Spartanburg International Airport (GSP)plane STS - GSP
18h 22m$241–900Bus
- Take the bus from Santa Rosa to Phoenix Bus Stationbus
- Take the bus from Phoenix Bus Station to Dallas Bus Stationbus
- Take the bus from Dallas Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus
2d 19h$396–642Bus, train
- Take the bus from Santa Rosa Amtrak Bus Stop to Martinezbus
- Take the train from Martinez to Chicago Union Stationtrain
- Take the bus from Chicago Train Station to Atlanta Bus Stationbus
- Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus
3d 4h$773–1,674Drive 2,643.1 mi
- Drive from Santa Rosa to Greenvillecar 2,643.1 mi
42h 33m$483–697Train, bus to San Francisco International Airport, fly
- Take the train from SMART Santa Rosa Downtown to SMART Larkspurtrain
- Take the bus from Larkspur - pickup to San Francisco Airportbus
- Fly from San Francisco International Airport (SFO) to Greenville–Spartanburg International Airport (GSP)plane SFO - GSP
10h 29m$268–934Train, bus to Oakland International Airport, fly
- Take the train from SMART Santa Rosa Downtown to SMART San Rafaeltrain
- Take the bus from San Rafael to Oakland International Airportbus
- Fly from Oakland International Airport (OAK) to Greenville–Spartanburg International Airport (GSP)plane OAK - GSP
12h 45m$301–1,106
Sonoma County Airport (STS) to Greenville–Spartanburg International Airport (GSP) flights
Comparing Your Travel Options
The cheapest way to get from Santa Rosa to Greenville is to bus which costs $390 - $650 and takes 2 days 19h.
The fastest way to get from Santa Rosa to Greenville is to train and bus and fly which takes 10h 29m and costs $260 - $950.
No, there is no direct bus from Santa Rosa to Greenville. However, there are services departing from Santa Rosa and arriving at Taqueria Guadalajara - Greenville via Phoenix Bus Station, Dallas Bus Station, Lindbergh Center Station - Bay D and Atlanta. The journey, including transfers, takes approximately 2 days 19h.
The distance between Santa Rosa and Greenville is 2279 miles. The road distance is 2658.5 miles.
The best way to get from Santa Rosa to Greenville without a car is to bus which takes 2 days 19h and costs $390 - $650.
It takes approximately 18h 22m to get from Santa Rosa to Greenville, including transfers.
Santa Rosa to Greenville bus services, operated by ACN Autobuses, depart from Santa Rosa station.
The best way to get from Santa Rosa to Greenville is to fly which takes 18h 22m and costs $240 - $900. Alternatively, you can bus, which costs $390 - $650 and takes 2 days 19h.
Santa Rosa to Greenville bus services, operated by ACN Autobuses, arrive at Phoenix Bus Station.
Greenville is 3h ahead of Santa Rosa. It is currently 6:55 AM in Santa Rosa and 9:55 AM in Greenville.
What companies run services between Santa Rosa, CA, USA and Greenville, SC, USA?
American Airlines, Southwest Airlines, and two other airlines fly from Sonoma County Airport (STS) to Greenville–Spartanburg International Airport (GSP) 3 times a day. Alternatively, you can take a bus from Santa Rosa to Greenville via Phoenix Bus Station, Dallas Bus Station, Atlanta Bus Station, Garnett Station, Lindbergh Center Station, Lindbergh Center Station - Bay D, Shallowford Rd @ New Peachtree, Atlanta, and Taqueria Guadalajara - Greenville in around 2d 19h.
- Website
- southwest.com
Flights from Sonoma County Airport to Greenville–Spartanburg International Airport via Las Vegas, Nashville
- Ave. Duration
- 18h 56m
- When
- Monday, Friday, Saturday, and Tuesday
- Estimated price
- $190–800
Flights from Sonoma County Airport to Greenville–Spartanburg International Airport via Denver, Nashville
- Ave. Duration
- 19h 45m
- When
- Sunday and Saturday
- Estimated price
- $190–800
Flights from Sonoma County Airport to Greenville–Spartanburg International Airport via Phoenix, Nashville
- Ave. Duration
- 16h 49m
- When
- Monday, Tuesday, Friday, and Saturday
- Estimated price
- $200–850
Flights from San Francisco International Airport to Greenville–Spartanburg International Airport via Nashville
- Ave. Duration
- 10h 5m
- When
- Monday, Tuesday, Friday, and Saturday
- Estimated price
- $200–850
Flights from Oakland International Airport to Greenville–Spartanburg International Airport via Las Vegas, Nashville
- Ave. Duration
- 9h 56m
- When
- Tuesday to Friday
- Estimated price
- $240–1,000
Flights from Oakland International Airport to Greenville–Spartanburg International Airport via Denver, Nashville
- Ave. Duration
- 9h 57m
- When
- Saturday to Friday
- Estimated price
- $240–1,000
Flights from Oakland International Airport to Greenville–Spartanburg International Airport via Dallas, Nashville
- Ave. Duration
- 10h
- When
- Tuesday, Wednesday, and Sunday
- Estimated price
- $250–1,100
Flights from Oakland International Airport to Greenville–Spartanburg International Airport via Burbank, Nashville
- Ave. Duration
- 9h 15m
- When
- Tuesday and Wednesday
- Estimated price
- $250–1,100
Flights from Oakland International Airport to Greenville–Spartanburg International Airport via Ontario/San Bernardino, Nashville
- Ave. Duration
- 10h 35m
- When
- Sunday
- Estimated price
- $250–1,100
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Martinez to Chicago Union Station
- Ave. Duration
- 2d 3h
- Frequency
- Once daily
- Estimated price
- $600–1,400
- Website
- Amtrak
- Phone
- +52 664 299 0487
- [email protected]
- Website
- acnautobuses.com
Bus from Santa Rosa to Phoenix Bus Station
- Ave. Duration
- 21h 10m
- Frequency
- Once daily
- Estimated price
- $60–90
- Schedules at
- acnautobuses.com
- Book at
- acnautobuses.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
Booking & Getting There
Yes, the driving distance between Santa Rosa to Greenville is 2659 miles. It takes approximately 42h 33m to drive from Santa Rosa to Greenville.
There are 272+ hotels available in Greenville.










