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How to get fromSanta Rosa to Medfordby plane, bus (Amtrak), bus, train, or car

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There are 5 ways to get from Santa Rosa to Medford by plane, bus (Amtrak), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Sonoma County Airport

    best
    1. Fly from Sonoma County Airport (STS) to Rogue Valley International - Medford Airport (MFR)plane plane STS - MFR
    5h 3m
    $466–655

  2. Drive 340 mi

    cheapest
    1. Drive from Santa Rosa to Medfordcar car 340 mi
    6h 17m
    $62–90

  3. Bus

    1. Take the bus from Santa Rosa Amtrak Bus Stop to Arcatabus bus
    2. Take the bus from Arcata Transit Center to Grocery Outletbus bus 20
    3. Take the bus from Crescent City Cultural Center/CoC to Front Street Station - Medfordbus bus
    14h 34m
    $91–140

  4. Bus, train

    1. Take the bus from Santa Rosa Amtrak Bus Stop to Martinezbus bus
    2. Take the train from Martinez to Klamath Fallstrain train
    3. Take the bus from Klamath Falls to 200 S Front St - Medfordbus bus
    14h 52m
    $128–299

  5. Train, bus to San Francisco International Airport, fly

    1. Take the train from SMART Santa Rosa Downtown to SMART Larkspurtrain train
    2. Take the bus from Larkspur - pickup to San Francisco Airportbus bus
    3. Fly from San Francisco International Airport (SFO) to Rogue Valley International - Medford Airport (MFR)plane plane SFO - MFR
    5h 10m
    $163–279

Santa Rosa to Medford by bus

Calendar7Weekly Buses
Duration14h 34mAverage Duration
Ticket$91Cheapest Price
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Questions & Answers

Map of how to get from Santa Rosa to Medford.ExpandLaunch map view
  • Distance: 275.8 mi
  • Duration: 5h 3m

What companies run services between Santa Rosa, CA, USA and Medford, OR, USA?

Alaska Airlines, Inc. and American Airlines fly from Sonoma County Airport (STS) to Rogue Valley International - Medford Airport (MFR) every 4 hours. Alternatively, you can take a bus from Santa Rosa Amtrak Bus Stop to Front Street Station - Medford via Arcata Transit Center and Crescent City Cultural Center/CoC in around 14h 34m.

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