There are 7 ways to get from Santander to Palermo by plane, car, car ferry, bus, train, or ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Santander Airport (SDR) to Palermo Airport (PMO)plane SDR - PMO
5h 43m€79–152Drive, car ferry
- Drive from Santander to Port of Genoacar
- Take the car ferry from Port of Genoa to Port of Palermocarferry
33h 8m€296–441Bus, train via Karlsruhe
- Take the bus from Estación de autobuses de Santander to Bordeauxbus
- Take the train from Bordeaux St Jean to Karlsruhe Hbftrain Tgv
- Take the train from Karlsruhe Hauptbahnhof to Heilbronn Hauptbahnhoftrain
- Take the bus from Heilbronn ZOB - Fernbusbahnhof - Bahnhofstrasse 41 to Verona Porta Nuova Stationbus
- Take the train from Verona Porta Nuova to Roma Terminitrain Fr
- Take the train from Roma Termini to Palermo Centraletrain Ic
39h 38mBus
- Take the bus from Estación de autobuses de Santander to Bordeauxbus
- Take the bus from Bordeaux to Florence Villa Constanza Bus Stationbus
- Take the bus from Florence Villa Constanza Bus Station to Palermobus
42h 15m€236–419Train, ferry, car ferry
- Take the train from Santander to Madrid Chamartíntrain Alv / ...
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the ferry from Port de Barcelona to Port of Civitavecchiaferry
- Take the car ferry from Civitavecchia Port to Palermo Portocarferry
44h 8m€243–473Bus, train, ferry
- Take the bus from Estación de autobuses de Santander to Miranda De Ebrobus
- Take the train from Miranda De Ebro to Zaragoza-Deliciastrain Ic / ...
- Take the train from Zaragoza-Delicias to Barcelona-Paseo De Graciatrain Re
- Take the ferry from Port de Barcelona to Port of Civitavecchiaferry
- Take the ferry from Civitavecchia to Palermoferry
2d 1h€204–355Bus, train
- Take the bus from Estación de autobuses de Santander to Padovabus
- Take the train from Padova to Verona Porta Nuovatrain Fr
- Take the bus from Verona Porta Nuova Station to Palermo Piazza Cairolibus
2d 3h
Santander to Palermo by bus
Questions & Answers
The cheapest way to get from Santander to Palermo is to fly which costs €75 - €160 and takes 5h 43m.
The fastest way to get from Santander to Palermo is to fly which takes 5h 43m and costs €75 - €160.
No, there is no direct bus from Santander to Palermo. However, there are services departing from Estación de autobuses de Santander and arriving at Palermo via Bordeaux and Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 42h 15m.
The distance between Santander and Palermo is 1567 km.
The best way to get from Santander to Palermo without a car is to bus and train via Karlsruhe which takes 39h 38m and costs .
It takes approximately 5h 43m to get from Santander to Palermo, including transfers.
Santander to Palermo bus services, operated by FlixBus, depart from Estación de autobuses de Santander station.
The best way to get from Santander to Palermo is to fly which takes 5h 43m and costs €75 - €160. Alternatively, you can bus, which costs €230 - €420 and takes 42h 15m.
Santander to Palermo bus services, operated by FlixBus, arrive at Bordeaux station.
Book your Santander to Palermo bus tickets online with Omio and FlixBus.
What companies run services between Santander, Spain and Palermo, Italy?
Ryanair, Vueling Airlines, and three other airlines fly from Santander Airport (SDR) to Palermo Airport (PMO) twice daily. Alternatively, you can take a bus from Estación de autobuses de Santander to Palermo via Bordeaux and Florence Villa Constanza Bus Station in around 42h 15m.
- Website
- vueling.com
Flights from Santander Airport to Palermo Airport via Barcelona
- Ave. Duration
- 5h 5m
- When
- Thursday and Saturday
- Estimated price
- €60–240
Flights from Santander Airport to Palermo Airport via Madrid
- Ave. Duration
- 9h 50m
- When
- Monday, Thursday, and Saturday
- Estimated price
- €75–300
- Website
- iberia.com
Flights from Santander Airport to Palermo Airport via Barcelona
- Ave. Duration
- 5h 5m
- When
- Thursday and Saturday
- Estimated price
- €60–240
Flights from Santander Airport to Palermo Airport via Madrid
- Ave. Duration
- 9h 50m
- When
- Monday, Thursday, and Saturday
- Estimated price
- €75–300
- Website
- ryanair.com
Flights from Santander Airport to Palermo Airport via Bologna
- Ave. Duration
- 4h 50m
- When
- Thursday
- Estimated price
- €70–130
Flights from Santander Airport to Palermo Airport via Charleroi
- Ave. Duration
- 6h 10m
- When
- Saturday and Sunday
- Estimated price
- €70–130
- Website
- flyulendo.com
Flights from Santander Airport to Palermo Airport via Milan Malpensa
- Ave. Duration
- 9h 15m
- When
- Tuesday and Saturday
- Estimated price
- €50–230
- Website
- easyjet.com
Flights from Santander Airport to Palermo Airport via Milan Malpensa
- Ave. Duration
- 4h 55m
- When
- Saturday
- Estimated price
- €50–230
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Bordeaux St Jean to Karlsruhe Hbf
- Ave. Duration
- 6h 20m
- Frequency
- Twice a week
- Estimated price
- €230–360
- Website
- https://www.sncf-connect.com/en-en
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Karlsruhe Hauptbahnhof to Heilbronn Hauptbahnhof
- Ave. Duration
- 1h 9m
- Frequency
- Hourly
- Estimated price
- €14–23
- Website
- https://int.bahn.de/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Verona Porta Nuova to Roma Termini
- Ave. Duration
- 3h 23m
- Frequency
- Every 2 hours
- Estimated price
- €70–140
- Schedules at
- trenitalia.com
Train from Padova to Verona Porta Nuova
- Ave. Duration
- 44 min
- Frequency
- Every 30 minutes
- Estimated price
- €12–24
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Roma Termini to Palermo Centrale
- Ave. Duration
- 11h 44m
- Frequency
- Twice daily
- Estimated price
- €90–190
- Website
- https://www.trenitalia.com/en.html
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Santander to Madrid Chamartín
- Ave. Duration
- 4h 14m
- Frequency
- 3 times a day
- Estimated price
- €55–85
- Website
- https://www.renfe.com/es/en
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 29m
- Frequency
- 4 times a day
- Estimated price
- €75–120
- Website
- https://www.renfe.com/es/en
Train from Miranda De Ebro to Zaragoza-Delicias
- Ave. Duration
- 2h 55m
- Frequency
- Hourly
- Estimated price
- €29–45
- Website
- https://www.renfe.com/es/en
Train from Zaragoza-Delicias to Barcelona-Paseo De Gracia
- Ave. Duration
- 5h 43m
- Frequency
- 4 times a day
- Estimated price
- €40–65
- Website
- https://www.renfe.com/es/en
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 22m
- Frequency
- Every 30 minutes
- Estimated price
- €95–170
- Website
- https://www.renfe.com/es/en
- Phone
- +34 900 926 851
- [email protected]
- Website
- iryo.eu
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 31m
- Frequency
- Hourly
- Estimated price
- €60–130
- Website
- https://iryo.eu/en/home
- Phone
- +34 900 759 781
- Website
- ouigo.com
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 23m
- Frequency
- Every 2 hours
- Estimated price
- €55–100
- Website
- https://www.ouigo.com/es/en
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Padova to Verona Porta Nuova
- Ave. Duration
- 44 min
- Frequency
- Hourly
- Estimated price
- €10–21
- Website
- https://www.italotreno.it/en
- Phone
- +39 06 68475475
- [email protected]
- Website
- trenitalia.com
Train from Padova to Verona Porta Nuova
- Ave. Duration
- 44 min
- Frequency
- 4 times a day
- Estimated price
- €25–70
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €45–70
- 2nd Class
- €25–35
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Padova to Verona Porta Nuova
- Ave. Duration
- 1h 54m
- Frequency
- Hourly
- Estimated price
- €10–17
- Website
- https://www.trenitalia.com/en.html
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- https://www.flixbus.fr
Bus from Estación de autobuses de Santander to Bordeaux
- Ave. Duration
- 6h
- Frequency
- Once daily
- Estimated price
- €35–60
- Website
- https://www.flixbus.co.uk
Bus from Estación de autobuses de Santander to Bordeaux
- Ave. Duration
- 6h
- Frequency
- Once daily
- Estimated price
- €35–60
- Website
- https://www.flixbus.co.uk
Bus from Bordeaux to Florence Villa Constanza Bus Station
- Ave. Duration
- 17h 15m
- Frequency
- Once daily
- Estimated price
- €100–180
- Website
- https://www.flixbus.co.uk
Bus from Florence Villa Constanza Bus Station to Palermo
- Ave. Duration
- 17h
- Frequency
- Twice daily
- Estimated price
- €100–180
- Website
- https://www.flixbus.co.uk
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- onebus.it
Bus from Heilbronn ZOB - Fernbusbahnhof - Bahnhofstrasse 41 to Verona Porta Nuova Station
- Ave. Duration
- 6h 17m
- Frequency
- Once a week
- Website
- https://onebus.it/
Bus from Verona Porta Nuova Station to Palermo Piazza Cairoli
- Ave. Duration
- 23h 57m
- Frequency
- Once a week
- Website
- https://onebus.it/
- Phone
- +34 910 207 007
- Website
- alsa.com
Bus from Estación de autobuses de Santander to Miranda De Ebro
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- €14–30
- Website
- https://www.alsa.com/en/
- Phone
- +4-0263-21.55.00
- Website
- tabitatour.ro
Bus from Estación de autobuses de Santander to Padova
- Ave. Duration
- 25h 27m
- Frequency
- Twice a week
- Estimated price
- €120–150
- Schedules at
- tabitatour.ro
- Phone
- +39 010 209 4591
- [email protected]
- Website
- gnv.it
Car ferry from Port of Genoa to Port of Palermo
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €95–150
- Website
- https://www.gnv.it/en
Car ferry from Civitavecchia Port to Palermo Porto
- Ave. Duration
- 13h 15m
- Frequency
- Once a week
- Estimated price
- €55–85
- Website
- https://www.gnv.it/en
Ferry from Civitavecchia to Palermo
- Ave. Duration
- 13h 45m
- Frequency
- Once a week
- Estimated price
- €45–85
- Website
- https://www.gnv.it/en
- Phone
- +39.081.496.444
- [email protected]
- Website
- grimaldi-lines.com
Ferry from Port de Barcelona to Port of Civitavecchia
- Ave. Duration
- 20h
- Frequency
- 5 times a week
- Estimated price
- €75–130
- Website
- https://www.grimaldi-lines.com/en/
Ferry from Port de Barcelona to Port of Civitavecchia
- Ave. Duration
- 20h
- Frequency
- 5 times a week
- Estimated price
- €75–130
- Website
- https://www.grimaldi-lines.com/en/
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