There are 7 ways to get from Santander to Palermo by plane, car, car ferry, train, bus, or ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Santander Airport (SDR) to Palermo Airport (PMO)plane SDR - PMO
5h 43m€73–428Drive, car ferry
- Drive from Santander to Port of Genoacar
- Take the carferry from Port of Genoa to Port of Palermocarferry
33h 8m€300–448Train, bus
- Take the train from Santander to Madrid Chamartíntrain Ic / ...
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charlestrain
- Take the bus from Marseille to Genoabus
- Take the train from Genova P.Za Principe to Roma Terminitrain Fb / ...
- Take the train from Roma Termini to Palermo Centraletrain Ic
41h 18m€367–723Bus
- Take the bus from Estación de autobuses de Santander to Bordeauxbus
- Take the bus from Bordeaux to Florence Villa Constanza Bus Stationbus
- Take the bus from Florence Villa Constanza Bus Station to Palermobus
42h 15m€234–395Train, ferry, car ferry
- Take the train from Santander to Madrid Chamartíntrain Ic / ...
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the ferry from Port de Barcelona to Port of Genoaferry
- Take the carferry from Port of Genoa to Port of Palermocarferry
44h 37m€298–550Bus, car ferry
- Take the bus from Estación de autobuses de Santander to Bilbao Intermodalbus
- Take the bus from Bilbao to Nice Airportbus
- Take the bus from Nice Airport to Genoabus 798 / ...
- Take the carferry from Port of Genoa to Port of Palermocarferry
45h 5m€209–339Bus, train
- Take the bus from Estación de autobuses de Santander to Padovabus
- Take the train from Padova to Verona Porta Nuovatrain Fr
- Take the bus from Verona Porta Nuova Station to Palermo Piazza Cairolibus
2d 3h
Santander to Palermo by train and bus
Questions & Answers
The cheapest way to get from Santander to Palermo is to fly which costs €70 - €430 and takes 5h 43m.
The fastest way to get from Santander to Palermo is to fly which takes 5h 43m and costs €70 - €430.
No, there is no direct bus from Santander to Palermo. However, there are services departing from Estación de autobuses de Santander and arriving at Palermo via Bordeaux and Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 42h 15m.
The distance between Santander and Palermo is 1567 km.
The best way to get from Santander to Palermo without a car is to train and bus which takes 41h 18m and costs €360 - €750.
It takes approximately 5h 43m to get from Santander to Palermo, including transfers.
Santander to Palermo bus services, operated by FlixBus, depart from Estación de autobuses de Santander station.
The best way to get from Santander to Palermo is to fly which takes 5h 43m and costs €70 - €430. Alternatively, you can bus, which costs €230 - €400 and takes 42h 15m.
Santander to Palermo bus services, operated by FlixBus, arrive at Bordeaux station.
Book your Santander to Palermo bus tickets online with Omio and FlixBus.
What companies run services between Santander, Spain and Palermo, Italy?
Vueling Airlines, Ryanair, and three other airlines fly from Santander Airport (SDR) to Palermo Airport (PMO) twice daily. Alternatively, you can take a bus from Estación de autobuses de Santander to Palermo via Bordeaux and Florence Villa Constanza Bus Station in around 42h 15m.
- Website
- vueling.com
Flights from Santander Airport to Palermo Airport via Barcelona
- Ave. Duration
- 5h 5m
- When
- Thursday and Saturday
- Estimated price
- €55–240
Flights from Santander Airport to Palermo Airport via Madrid
- Ave. Duration
- 9h 50m
- When
- Monday, Thursday, and Saturday
- Estimated price
- €80–300
- Website
- iberia.com
Flights from Santander Airport to Palermo Airport via Barcelona
- Ave. Duration
- 5h 5m
- When
- Thursday and Saturday
- Estimated price
- €55–240
Flights from Santander Airport to Palermo Airport via Madrid
- Ave. Duration
- 9h 50m
- When
- Monday, Thursday, and Saturday
- Estimated price
- €80–300
- Website
- ryanair.com
Flights from Santander Airport to Palermo Airport via Bologna
- Ave. Duration
- 4h 50m
- When
- Thursday
- Estimated price
- €65–260
Flights from Santander Airport to Palermo Airport via Charleroi
- Ave. Duration
- 6h 10m
- When
- Saturday and Sunday
- Estimated price
- €75–270
- Website
- flyulendo.com
Flights from Santander Airport to Palermo Airport via Milan Malpensa
- Ave. Duration
- 9h 15m
- When
- Tuesday and Saturday
- Estimated price
- €55–250
- Website
- easyjet.com
Flights from Santander Airport to Palermo Airport via Milan Malpensa
- Ave. Duration
- 4h 55m
- When
- Saturday
- Estimated price
- €55–250
Rome2Rio's guide to Renfe Viajeros
Contact DetailsContact Details
- Phone
- +34 91 232 03 20
- Website
- Renfe Viajeros
Train from Santander to Madrid Chamartín
- Ave. Duration
- 4h 14m
- Frequency
- Every 4 hours
- Estimated price
- €55–85
- Website
- Renfe Viajeros
Train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charles
- Ave. Duration
- 8h 42m
- Frequency
- Twice daily
- Estimated price
- €140–230
- Website
- Renfe Viajeros
Train from Santander to Madrid Chamartín
- Ave. Duration
- 4h 14m
- Frequency
- Every 4 hours
- Estimated price
- €55–85
- Website
- Renfe Viajeros
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 29m
- Frequency
- 4 times a day
- Estimated price
- €80–130
- Website
- Renfe Viajeros
- Phone
- +39 06 68475475
- Website
- Trenitalia Frecce
Train from Genova P.Za Principe to Roma Termini
- Ave. Duration
- 4h 56m
- Frequency
- Hourly
- Estimated price
- €70–150
- Schedules at
- Trenitalia Frecce
Train from Padova to Verona Porta Nuova
- Ave. Duration
- 44 min
- Frequency
- Every 30 minutes
- Estimated price
- €12–24
- Schedules at
- Trenitalia Frecce
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Genova P.Za Principe to Roma Termini
- Ave. Duration
- 5h 40m
- Frequency
- Every 4 hours
- Estimated price
- €50–110
- Website
- Trenitalia Intercity
Train from Roma Termini to Palermo Centrale
- Ave. Duration
- 11h 38m
- Frequency
- Twice daily
- Estimated price
- €90–200
- Website
- Trenitalia Intercity
Rome2Rio's guide to Renfe AVE
Contact DetailsContact Details
- Phone
- +34 91 232 03 20
- Website
- Renfe AVE
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 22m
- Frequency
- Every 30 minutes
- Estimated price
- €95–170
- Website
- Renfe AVE
- Phone
- +34 900 926 851
- [email protected]
- Website
- Iryo
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 24m
- Frequency
- Hourly
- Estimated price
- €60–130
- Website
- Iryo
- Phone
- +34 900 759 781
- Website
- Ouigo
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 23m
- Frequency
- Every 2 hours
- Estimated price
- €55–100
- Website
- Ouigo
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Padova to Verona Porta Nuova
- Ave. Duration
- 44 min
- Frequency
- Hourly
- Estimated price
- €10–21
- Website
- Italo Treno
- Phone
- +39 06 68475475
- [email protected]
- Website
- Trenitalia Eurocity
Train from Padova to Verona Porta Nuova
- Ave. Duration
- 44 min
- Frequency
- 4 times a day
- Estimated price
- €25–70
- Website
- Trenitalia Eurocity
- 1st Class
- €45–70
- 2nd Class
- €25–35
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Padova to Verona Porta Nuova
- Ave. Duration
- 1h 54m
- Frequency
- Every 30 minutes
- Estimated price
- €10–17
- Website
- Trenitalia
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Marseille to Genoa
- Ave. Duration
- 8h
- Frequency
- Every 4 hours
- Estimated price
- €30–55
- Website
- Flixbus
Bus from Estación de autobuses de Santander to Bordeaux
- Ave. Duration
- 6h
- Frequency
- Once daily
- Estimated price
- €30–60
- Website
- Flixbus
Bus from Bordeaux to Florence Villa Constanza Bus Station
- Ave. Duration
- 17h 15m
- Frequency
- Once daily
- Estimated price
- €100–170
- Website
- Flixbus
Bus from Florence Villa Constanza Bus Station to Palermo
- Ave. Duration
- 17h
- Frequency
- Twice daily
- Estimated price
- €100–170
- Website
- Flixbus
Bus from Bilbao to Nice Airport
- Ave. Duration
- 16h 45m
- Frequency
- 3 times a week
- Estimated price
- €85–140
- Website
- Flixbus
Bus from Nice Airport to Genoa
- Ave. Duration
- 3h 10m
- Frequency
- Hourly
- Estimated price
- €15–26
- Website
- Flixbus
- Phone
- +34 910 207 007
- Website
- ALSA
Bus from Estación de autobuses de Santander to Bilbao Intermodal
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €8–14
- Website
- ALSA
- Phone
- +4-0263-21.55.00
- Website
- tabitatour.ro
Bus from Estación de autobuses de Santander to Padova
- Ave. Duration
- 25h 27m
- Frequency
- Twice a week
- Estimated price
- €120–150
- Schedules at
- tabitatour.ro
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from Verona Porta Nuova Station to Palermo Piazza Cairoli
- Ave. Duration
- 23h 57m
- Frequency
- Once a week
- Website
- Onebus
- Phone
- +39 010 209 4591
- [email protected]
- Website
- Grandi Navi Veloci
Car ferry from Port of Genoa to Port of Palermo
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €100–160
- Website
- Grandi Navi Veloci
Ferry from Port de Barcelona to Port of Genoa
- Ave. Duration
- 13h 5m
- Frequency
- 3 times a week
- Estimated price
- €85–130
- Website
- Grandi Navi Veloci
Car ferry from Port of Genoa to Port of Palermo
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €100–160
- Website
- Grandi Navi Veloci
Car ferry from Port of Genoa to Port of Palermo
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €100–160
- Website
- Grandi Navi Veloci
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