There are 6 ways to get from Santander to Palermo by plane, car, car ferry, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Santander Airport (SDR) to Palermo Airport (PMO)plane SDR - PMO
5h 52m€58–259Drive, car ferry
- Drive from Santander to Port of Genoacar
- Take the carferry from Port of Genoa to Port of Palermocarferry
33h 8m€308–451Bus, train
- Take the bus from Estación de autobuses de Santander to Bordeauxbus
- Take the train from Bordeaux St Jean to Massy Tgvtrain Tgv
- Take the train from Massy Tgv to Lyon Part Dieutrain Tgv
- Take the train from Lyon Part Dieu to Milano Centraletrain Fr
- Take the train from Milano Centrale to Roma Terminitrain
- Take the train from Roma Termini to Palermo Centraletrain Ic
33h 49m€408–711Bus
- Take the bus from Estación de autobuses de Santander to Bordeauxbus
- Take the bus from Bordeaux to Florence Villa Constanza Bus Stationbus
- Take the bus from Florence Villa Constanza Bus Station to Palermobus
42h 15m€258–396Bus, car ferry
- Take the bus from Estación de autobuses de Santander to Bilbao Intermodalbus
- Take the bus from Bilbao to Nice Airportbus
- Take the bus from Nice Airport to Genoabus 798 / ...
- Take the carferry from Port of Genoa to Port of Palermocarferry
44h 52m€218–329Bus via Metz
- Take the bus from Estación de autobuses de Santander to Bilbao Intermodalbus
- Take the bus from Bilbao Intermodal to Metz - Bus Stationbus
- Take the bus from METZ - Gare Routiere to Palermo Piazza Cairolibus
2d 6h€379–553
Santander to Palermo by bus
Comparing Your Travel Options
The cheapest way to get from Santander to Palermo is to fly which costs €55 - €260 and takes 5h 52m.
The fastest way to get from Santander to Palermo is to fly which takes 5h 52m and costs €55 - €260.
No, there is no direct bus from Santander to Palermo. However, there are services departing from Estación de autobuses de Santander and arriving at Palermo via Bordeaux and Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 42h 15m.
The distance between Santander and Palermo is 1567 km.
The best way to get from Santander to Palermo without a car is to bus and train which takes 33h 49m and costs €400 - €750.
It takes approximately 5h 52m to get from Santander to Palermo, including transfers.
Santander to Palermo bus services, operated by FlixBus, depart from Estación de autobuses de Santander station.
The best way to get from Santander to Palermo is to fly which takes 5h 52m and costs €55 - €260. Alternatively, you can bus, which costs €250 - €400 and takes 42h 15m.
Santander to Palermo bus services, operated by FlixBus, arrive at Bordeaux station.
Book your Santander to Palermo bus tickets online with Omio and FlixBus.
What companies run services between Santander, Spain and Palermo, Italy?
Vueling Airlines, Ryanair, and four other airlines fly from Santander Airport (SDR) to Palermo Airport (PMO) twice daily. Alternatively, you can take a bus from Estación de autobuses de Santander to Palermo via Bordeaux and Florence Villa Constanza Bus Station in around 42h 15m.
- Website
- ryanair.com
Flights from Santander Airport to Palermo Airport via Bologna
- Ave. Duration
- 9h 20m
- When
- Sunday
- Estimated price
- €70–270
Flights from Santander Airport to Palermo Airport via Milan Malpensa
- Ave. Duration
- 4h 50m
- When
- Friday
- Estimated price
- €50–260
Flights from Santander Airport to Palermo Airport via Madrid
- Ave. Duration
- 6h 40m
- When
- Sunday and Saturday
- Estimated price
- €65–270
- Website
- iberia.com
Flights from Santander Airport to Palermo Airport via Barcelona
- Ave. Duration
- 8h 20m
- When
- Wednesday, Friday, and Sunday
- Estimated price
- €60–270
Flights from Santander Airport to Palermo Airport via Madrid
- Ave. Duration
- 10h 15m
- When
- Saturday
- Estimated price
- €75–330
- Website
- vueling.com
Flights from Santander Airport to Palermo Airport via Barcelona
- Ave. Duration
- 8h 20m
- When
- Wednesday, Friday, and Sunday
- Estimated price
- €60–270
- Website
- easyjet.com
Flights from Santander Airport to Palermo Airport via Palma Mallorca
- Ave. Duration
- 5h 10m
- When
- Monday and Friday
- Estimated price
- €65–290
- Website
- transavia.com
Flights from Santander Airport to Palermo Airport via Paris Orly
- Ave. Duration
- 6h 20m
- When
- Saturday
- Estimated price
- €100–470
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Bordeaux St Jean to Massy Tgv
- Ave. Duration
- 2h 3m
- Frequency
- 4 times a day
- Estimated price
- €100–160
- Website
- TGV inOui
Train from Massy Tgv to Lyon Part Dieu
- Ave. Duration
- 2h 4m
- Frequency
- Every 4 hours
- Estimated price
- €85–130
- Website
- TGV inOui
- Phone
- +33 1 84 94 36 35
- Website
- Oui.SNCF
Train from Bordeaux St Jean to Massy Tgv
- Ave. Duration
- 2h 59m
- Frequency
- Once daily
- Estimated price
- €90–160
- Website
- Oui.SNCF
Train from Massy Tgv to Lyon Part Dieu
- Ave. Duration
- 2h 4m
- Frequency
- Every 4 hours
- Estimated price
- €75–130
- Website
- Oui.SNCF
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Lyon Part Dieu to Milano Centrale
- Ave. Duration
- 4h 44m
- Frequency
- Twice daily
- Estimated price
- €50–75
- Website
- Trenitalia
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Milano Centrale to Roma Termini
- Ave. Duration
- 3h 5m
- Frequency
- Every 30 minutes
- Estimated price
- €65–120
- Website
- Italo Treno
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Roma Termini to Palermo Centrale
- Ave. Duration
- 11h 32m
- Frequency
- Twice daily
- Estimated price
- €90–170
- Website
- Trenitalia Intercity
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Estación de autobuses de Santander to Bordeaux
- Ave. Duration
- 6h
- Frequency
- Once daily
- Estimated price
- €35–60
- Website
- Flixbus
Bus from Estación de autobuses de Santander to Bordeaux
- Ave. Duration
- 6h
- Frequency
- Once daily
- Estimated price
- €35–60
- Website
- Flixbus
Bus from Bordeaux to Florence Villa Constanza Bus Station
- Ave. Duration
- 17h 15m
- Frequency
- 5 times a week
- Estimated price
- €110–170
- Website
- Flixbus
Bus from Florence Villa Constanza Bus Station to Palermo
- Ave. Duration
- 17h
- Frequency
- Twice daily
- Estimated price
- €110–170
- Website
- Flixbus
Bus from Bilbao to Nice Airport
- Ave. Duration
- 16h 45m
- Frequency
- 3 times a week
- Estimated price
- €95–140
- Website
- Flixbus
Bus from Nice Airport to Genoa
- Ave. Duration
- 3h 10m
- Frequency
- Every 3 hours
- Estimated price
- €17–26
- Website
- Flixbus
- Phone
- +34 910 207 007
- Website
- ALSA
Bus from Estación de autobuses de Santander to Bilbao Intermodal
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €8–14
- Website
- ALSA
Bus from Estación de autobuses de Santander to Bilbao Intermodal
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €8–14
- Website
- ALSA
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Nice Airport to Genoa
- Ave. Duration
- 3h 10m
- Frequency
- Every 2 hours
- Estimated price
- €14–24
- Website
- BlaBlaCar Bus
Bus from Bilbao Intermodal to Metz - Bus Station
- Ave. Duration
- 17h 29m
- Frequency
- 3 times a day
- Estimated price
- €90–150
- Website
- BlaBlaCar Bus
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from METZ - Gare Routiere to Palermo Piazza Cairoli
- Ave. Duration
- 33h 15m
- Frequency
- Once a week
- Estimated price
- €280–390
- Website
- Onebus
- Phone
- +39 010 209 4591
- [email protected]
- Website
- Grandi Navi Veloci
Car ferry from Port of Genoa to Port of Palermo
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €100–150
- Website
- Grandi Navi Veloci
Car ferry from Port of Genoa to Port of Palermo
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €100–150
- Website
- Grandi Navi Veloci
Want to know more about travelling around Italy
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