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How to get fromSantander to Sicilyby plane, car, car ferry, bus, or train

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There are 8 ways to get from Santander to Sicily by plane, car, car ferry, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Palermo Airport

    best
    1. Fly from Santander Airport (SDR) to Palermo Airport (PMO)plane plane SDR - PMO
    5h 52m
    €58–259

  2. Drive, car ferry

    1. Drive from Santander to Port of Genoacar car
    2. Take the carferry from Port of Genoa to Port of Palermocarferry car ferry
    33h 16m
    €309–452

  3. Bus

    1. Take the bus from Estación de autobuses de Santander to Bordeauxbus bus
    2. Take the bus from Bordeaux to Florence Villa Constanza Bus Stationbus bus
    3. Take the bus from Florence Villa Constanza Bus Station to Palermobus bus
    42h 46m
    €260–398

  4. Fly to Catania–Fontanarossa Airport

    1. Fly from Santander Airport (SDR) to Catania–Fontanarossa Airport (CTA)plane plane SDR - CTA
    5h 2m
    €58–245

  5. Train, bus, car ferry

    1. Take the train from Santander to Madrid Chamartíntrain train Alv / ...
    2. Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charlestrain train
    3. Take the bus from Marseille - Saint-Charles Bus Station to Genoa - Via Fanti d'Italia Bus Stopbus bus
    4. Take the carferry from Port of Genoa to Port of Palermocarferry car ferry
    43h 6m
    €326–493

  6. Train, bus

    1. Take the train from Santander to Basurto Hospitaltrain train
    2. Take the bus from Bilbao to Toulonbus bus
    3. Take the bus from Toulon to Napoli P.zza Garibaldibus bus
    4. Take the train from Napoli Centrale to Palermo Centraletrain train Ic
    44h 44m
    €250–423

  7. Bus, car ferry

    1. Take the bus from Estación de autobuses de Santander to Bilbao Intermodalbus bus
    2. Take the bus from Bilbao to Nice Airportbus bus
    3. Take the bus from Nice Airport to Genoabus bus 798 / ...
    4. Take the carferry from Port of Genoa to Port of Palermocarferry car ferry
    45h 43m
    €220–331

  8. Bus via Metz

    1. Take the bus from Estación de autobuses de Santander to Bilbao Intermodalbus bus
    2. Take the bus from Bilbao Intermodal to Metz - Bus Stationbus bus
    3. Take the bus from METZ - Gare Routiere to Palermo Piazza Cairolibus bus
    2d 6h
    €381–555

Santander to Sicily by bus

Calendar5Weekly Buses
Duration42h 46mAverage Duration
Ticket€260Cheapest Price
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Comparing Your Travel Options

Map of how to get from Santander to Sicily.ExpandLaunch map view
  • Distance: 1,566.6 km
  • Duration: 5h 52m

What companies run services between Santander, Spain and Sicily, Italy?

Vueling Airlines, Ryanair, and four other airlines fly from Santander Airport (SDR) to Palermo Airport (PMO) twice daily. Alternatively, you can take a bus from Estación de autobuses de Santander to Piazza Boiardo via Bordeaux, Florence Villa Constanza Bus Station, Palermo, and Stazione Centrale Pensilina Esterna in around 42h 46m.

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