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How to get fromSantander to Sicilyby plane, car, car ferry, bus, train, or ferry

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There are 8 ways to get from Santander to Sicily by plane, car, car ferry, bus, train, or ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Palermo Airport

    best
    1. Fly from Santander Airport (SDR) to Palermo Airport (PMO)plane plane SDR - PMO
    5h 43m
    €78–152

  2. Drive, car ferry

    1. Drive from Santander to Port of Genoacar car
    2. Take the car ferry from Port of Genoa to Port of Palermocarferry car ferry
    33h 15m
    €297–442

  3. Bus

    1. Take the bus from Estación de autobuses de Santander to Bordeauxbus bus
    2. Take the bus from Bordeaux to Florence Villa Constanza Bus Stationbus bus
    3. Take the bus from Florence Villa Constanza Bus Station to Palermobus bus
    42h 48m
    €238–421

  4. Fly to Catania–Fontanarossa Airport

    1. Fly from Santander Airport (SDR) to Catania–Fontanarossa Airport (CTA)plane plane SDR - CTA
    6h 17m
    €92–285

  5. Train, ferry, car ferry

    1. Take the train from Santander to Madrid Chamartíntrain train Alv / ...
    2. Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain train Ave
    3. Take the ferry from Port de Barcelona to Port of Civitavecchiaferry ferry
    4. Take the car ferry from Civitavecchia Port to Palermo Portocarferry car ferry
    44h 8m
    €243–473

  6. Train, bus

    1. Take the train from Santander to Basurto Hospitaltrain train
    2. Take the bus from Bilbao to Toulonbus bus
    3. Take the bus from Toulon to Napoli P.zza Garibaldibus bus
    4. Take the train from Napoli Centrale to Palermo Centraletrain train Ic
    44h 42m
    €240–454

  7. Bus, car ferry

    1. Take the bus from Estación de autobuses de Santander to Bilbao Intermodalbus bus
    2. Take the bus from Bilbao to Nice Airportbus bus
    3. Take the bus from Nice Airport to Genoabus bus 798 / ...
    4. Take the car ferry from Port of Genoa to Port of Palermocarferry car ferry
    45h 38m
    €206–353

  8. Bus via Metz

    1. Take the bus from Estación de autobuses de Santander to Bilbao Intermodalbus bus
    2. Take the bus from Bilbao Intermodal to Metz - Bus Stationbus bus
    3. Take the bus from METZ - Gare Routiere to Palermo Piazza Cairolibus bus
    2d 6h

Santander to Sicily by bus

Calendar7Weekly Buses
Duration42h 48mAverage Duration
Ticket€238Cheapest Price
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Questions & Answers

Map of how to get from Santander to Sicily.ExpandLaunch map view
  • Distance: 1,566.6 km
  • Duration: 5h 43m

What companies run services between Santander, Spain and Sicily, Italy?

Ryanair, Vueling Airlines, and three other airlines fly from Santander Airport (SDR) to Palermo Airport (PMO) twice daily. Alternatively, you can take a bus from Estación de autobuses de Santander to Piazza Boiardo via Bordeaux, Florence Villa Constanza Bus Station, Palermo, and Stazione Centrale Pensilina Esterna in around 42h 48m.

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