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How to get fromSantander to Sienaby plane, train, bus, or car

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There are 8 ways to get from Santander to Siena by plane, train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Florence Peretola Airport, train

    best
    1. Fly from Santander Airport (SDR) to Florence Peretola Airport (FLR)plane plane SDR - FLR
    2. Take the train from Firenze S.M.N. to Sienatrain train
    7h 3m
    €102–344

  2. Fly to Pisa International Airport, train

    cheapest
    1. Fly from Santander Airport (SDR) to Pisa International Airport (PSA)plane plane SDR - PSA
    2. Take the train from Pisa Centrale to Empolitrain train
    3. Take the train from Empoli to Sienatrain train
    7h 6m
    €84–196

  3. Train, bus

    1. Take the train from Santander to Madrid Chamartíntrain train Alv / ...
    2. Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Perpignantrain train
    3. Take the bus from Perpignan to Florencebus bus
    4. Take the train from Firenze S.M.N. to Sienatrain train Re
    25h 51m
    €235–378

  4. Drive 1,538.7 km

    1. Drive from Santander to Sienacar car 1,538.7 km
    15h 37m
    €244–352

  5. Fly to Bologna Guglielmo Marconi Airport, train

    1. Fly from Santander Airport (SDR) to Bologna Guglielmo Marconi Airport (BLQ)plane plane SDR - BLQ
    2. Take the train from Bologna Centrale to Firenze S.M.N.train train
    3. Take the train from Firenze S.M.N. to Sienatrain train
    4h 57m
    €84–241

  6. Bus

    1. Take the bus from Estación de autobuses de Santander to Bordeauxbus bus
    2. Take the bus from Bordeaux to Florence Villa Constanza Bus Stationbus bus
    3. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus 443 / ...
    26h 5m
    €133–220

  7. Bus, train

    1. Take the bus from Estación de autobuses de Santander to Padovabus bus
    2. Take the train from Padova to Firenze S.M.N.train train Fr
    3. Take the train from Firenze S.M.N. to Sienatrain train Re
    29h 30m
    €160–229

  8. Bus via Chamonix

    1. Take the bus from Estación de autobuses de Santander to Bilbao Intermodalbus bus
    2. Take the bus from Bilbao Intermodal to Chamonix, Av. de Courmayeur (Gare routière Sud)bus bus
    3. Take the bus from Chamonix, Av. de Courmayeur (Gare routière Sud) to Florence Villa Constanza Bus Stationbus bus
    4. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131
    31h 49m
    €151–281

Santander to Siena by train, bus, and tram

Calendar14Weekly Services
Duration25h 51mAverage Duration
Ticket€235Cheapest Price
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Questions & Answers

Map of how to get from Santander to Siena.ExpandLaunch map view
  • Distance: 1,306.8 km
  • Duration: 7h 3m

What companies run services between Santander, Spain and Siena, Italy?

You can take a bus from Estación de autobuses de Santander to Siena via Bordeaux and Florence Villa Constanza Bus Station in around 26h 5m.

Airlines
Train operators
Bus operators

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