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How to get fromSantander to Sienaby plane, train, bus, or car

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There are 8 ways to get from Santander to Siena by plane, train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Florence Peretola Airport, train

    best
    1. Fly from Santander Airport (SDR) to Florence Peretola Airport (FLR)plane plane SDR - FLR
    2. Take the train from Firenze S.M.N. to Sienatrain train
    8h 3m
    €105–352

  2. Fly to Pisa International Airport, train

    cheapest
    1. Fly from Santander Airport (SDR) to Pisa International Airport (PSA)plane plane SDR - PSA
    2. Take the train from Pisa Centrale to Empolitrain train
    3. Take the train from Empoli to Sienatrain train
    7h 6m
    €73–320

  3. Bus, train via Montpellier

    1. Take the bus from Estación de autobuses de Santander to Bilbao Intermodalbus bus
    2. Take the bus from Bilbao Intermodal to Montpellierbus bus
    3. Take the train from Montpellier Sud De France to Lyon Part Dieutrain train Tgv
    4. Take the train from Lyon Part Dieu to Milano Centraletrain train Fr
    5. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    6. Take the train from Firenze S.M.N. to Sienatrain train Re
    24h 34m
    €210–359

  4. Drive  1,538.7 km

    1. Drive from Santander to Sienacar car 1,538.7 km
    15h 37m
    €252–364

  5. Train, bus

    1. Take the train from Santander to Madrid Chamartíntrain train Alv / ...
    2. Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Perpignantrain train
    3. Take the bus from Perpignan to Florencebus bus
    4. Take the train from Firenze S.M.N. to Sienatrain train Re
    26h 2m
    €244–369

  6. Bus

    1. Take the bus from Estación de autobuses de Santander to Bordeauxbus bus
    2. Take the bus from Bordeaux to Florence Villa Constanza Bus Stationbus bus
    3. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus 443 / ...
    26h 5m
    €153–236

  7. Bus, train

    1. Take the bus from Estación de autobuses de Santander to Padovabus bus
    2. Take the train from Padova to Firenze S.M.N.train train Fr
    3. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131
    29h 34m
    €151–201

  8. Bus via Turin

    1. Take the bus from Estación de autobuses de Santander to Bilbao Intermodalbus bus
    2. Take the bus from Bilbao Intermodal to Bordeaux - Belcier Bus Stopbus bus
    3. Take the bus from Bordeaux - Belcier Bus Stop to Turin - Vittorio Emanuele Bus Stationbus bus
    4. Take the bus from Turin Stura Bus Station to Siena Central Train Stationbus bus
    31h 2m
    €126–225

Santander to Siena by bus and train

Calendar5Weekly Services
Duration24h 34mAverage Duration
Ticket€210Cheapest Price
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Comparing Your Travel Options

Map of how to get from Santander to Siena.ExpandLaunch map view
  • Distance: 1,306.8 km
  • Duration: 8h 3m

What companies run services between Santander, Spain and Siena, Italy?

You can take a bus from Estación de autobuses de Santander to Siena via Bordeaux and Florence Villa Constanza Bus Station in around 26h 5m.

Airlines
Train operators
Bus operators

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