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How to get fromSantee to Floridaby bus (Flixbus, Greyhound), taxi, train, car, or plane

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There are 8 ways to get from Santee to Florida by bus (Flixbus, Greyhound), taxi, train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Orangeburg to Jacksonvillebus bus FlixBus 2433
    5h 8m
    $118–163

  2. Drive  240.4 mi

    cheapest
    1. Drive from Santee to Jacksonvillecar car 240.4 mi
    3h 55m
    $44–64

  3. Taxi, train (Amtrak)

    1. Take the taxi from Santee to Denmark Amtrak Stationtaxi taxi
    2. Take the train from Denmark Amtrak Station to Jacksonvilletrain train Floridian
    6h 46m
    $203–316

  4. Drive, fly to Fort Lauderdale–Hollywood International Airport

    1. Drive from Santee to Charleston-Airport-CHScar car
    2. Fly from Charleston International Airport (CHS) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane CHS - FLL
    3h 19m
    $413–1,119

  5. Drive, fly to Miami International Airport

    1. Drive from Santee to Charleston-Airport-CHScar car
    2. Fly from Charleston International Airport (CHS) to Miami International Airport (MIA)plane plane CHS - MIA
    3h 14m
    $504–1,019

  6. Drive, fly to Tampa

    1. Drive from Santee to Charleston-Airport-CHScar car
    2. Fly from Charleston International Airport (CHS) to Tampa (TPA)plane plane CHS - TPA
    3h 41m
    $153–308

  7. Drive, fly to Orlando

    1. Drive from Santee to Charleston-Airport-CHScar car
    2. Fly from Charleston International Airport (CHS) to Orlando (MCO)plane plane CHS - MCO
    3h 56m
    $90–281

  8. Drive, fly to Ft. Myers

    1. Drive from Santee to Charleston-Airport-CHScar car
    2. Fly from Charleston International Airport (CHS) to Ft. Myers (RSW)plane plane CHS - RSW
    5h 13m
    $114–571

Charleston International Airport (CHS) to Fort Lauderdale–Hollywood International Airport (FLL) flights

Calendar39Weekly Planes
Duration3h 3mAverage Duration
Ticket$72Cheapest Price
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Comparing Your Travel Options

Map of how to get from Santee to Florida.ExpandLaunch map view
  • Distance: 271.3 mi
  • Duration: 5h 8m

What companies run services between Santee, SC, USA and Florida, USA?

Flixbus USA operates a bus from Orangeburg to Jacksonville once daily. Tickets cost $35–55 and the journey takes 4h 40m. Greyhound USA also services this route once daily.

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