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How to get fromSantee to San Franciscoby tram, plane, bus (Greyhound), train (Amtrak), car, train, or bus (Flixbus)

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There are 7 ways to get from Santee to San Francisco by tram, plane, bus (Greyhound), train (Amtrak), car, train, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Tram, fly to San Francisco International Airport

    best
    1. Take the tram from El Cajon Station to Old Town Stationtram tram
    2. Fly from San Diego International Airport (SAN) to San Francisco International Airport (SFO)plane plane SAN - SFO
    4h 23m
    $78–282

  2. Bus

    1. Take the bus from San Diego Greyhound Bus Stop to San Francisco Bus Stationbus bus Greyhound US0831
    13h 24m
    $80–180

  3. Train (Amtrak)

    1. Take the train from San Diego Old Town Transportation Center to Oxnardtrain train Pacific Surfliner
    2. Take the train from Oxnard to Oaklandtrain train Coast Starlight
    18h 5m
    $198–434

  4. Drive 504.3 mi

    1. Drive from Santee to San Franciscocar car 504.3 mi
    8h 29m
    $92–133

  5. Tram, fly to Oakland International Airport

    1. Take the tram from El Cajon Station to Old Town Stationtram tram
    2. Fly from San Diego International Airport (SAN) to Oakland International Airport (OAK)plane plane SAN - OAK
    4h 38m
    $84–298

  6. Fly to Norman Y. Mineta San José International Airport, Caltrain

    1. Fly from San Diego International Airport (SAN) to Norman Y. Mineta San José International Airport (SJC)plane plane SAN - SJC
    2. Take the train from Santa Clara Caltrain Northbound to San Francisco Caltrain Northboundtrain train
    5h 39m
    $86–315

  7. Bus via Los Angeles

    1. Take the bus from San Diego to Los Angeles Union Stationbus bus FlixBus 2017
    2. Take the bus from Los Angeles Union Station to San Franciscobus bus FlixBus 2005
    15h 30m
    $96–190

Santee to San Francisco by tram and bus

Calendar14Weekly Services
Duration13h 24mAverage Duration
Ticket$80Cheapest Price
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Questions & Answers

Map of how to get from Santee to San Francisco.ExpandLaunch map view
  • Distance: 484.2 mi
  • Duration: 4h 23m

What companies run services between Santee, CA, USA and San Francisco, CA, USA?

Greyhound USA operates a bus from San Diego Greyhound Bus Stop to San Francisco Bus Station once daily. Tickets cost $75–150 and the journey takes 11h 25m. Greyhound-us also services this route once daily. Alternatively, you can take a vehicle from Santee Town Center Station to Civic Center / UN Plaza via El Cajon Station, Old Town Station, San Diego Old Town Transportation Center, Oxnard, Oakland, and Lake Merritt in around 18h 5m.

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