There are 8 ways to get from Santiago to Santa Fe by bus or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to David, fly to Rosario – Islas Malvinas International Airport, bus
best- Take the bus from Santiago to Davidbus
- Fly from David (DAV) to Rosario – Islas Malvinas International Airport (ROS)plane DAV - ROS
- Take the bus from Terminal de Rosario Mariano Moreno to Terminal de Santa Fe Gral. Belgranobus
23h 22mBus to Tocumen International Airport, fly to Ingeniero Aeronáutico Ambrosio L.V. Taravella International Airport, bus
cheapest- Take the bus from Santiago to Paraíso, Panamá Provincebus
- Fly from Tocumen International Airport (PTY) to Ingeniero Aeronáutico Ambrosio L.V. Taravella International Airport (COR)plane PTY - COR
- Take the bus from Terminal de Ómnibus Córdoba T1 to Terminal de Santa Fe Gral. Belgranobus
20h 39m$413,510–1,361,610Bus to Tocumen International Airport, fly to Rosario – Islas Malvinas International Airport, bus
- Take the bus from Santiago to Paraíso, Panamá Provincebus
- Fly from Tocumen International Airport (PTY) to Rosario – Islas Malvinas International Airport (ROS)plane PTY - ROS
- Take the bus from Terminal de Rosario Mariano Moreno to Terminal de Santa Fe Gral. Belgranobus
19h 34m$901,952–1,714,952Bus to Tocumen International Airport, fly to General Justo José De Urquiza Airport
- Take the bus from Santiago to Paraíso, Panamá Provincebus
- Fly from Tocumen International Airport (PTY) to General Justo José De Urquiza Airport (PRA)plane PTY - PRA
20h 56m$560,890–1,826,890Bus to David, fly to Ingeniero Aeronáutico Ambrosio L.V. Taravella International Airport, bus
- Take the bus from Santiago to Davidbus
- Fly from David (DAV) to Ingeniero Aeronáutico Ambrosio L.V. Taravella International Airport (COR)plane DAV - COR
- Take the bus from Terminal de Ómnibus Córdoba T1 to Terminal de Santa Fe Gral. Belgranobus
21h 45mBus to Tocumen International Airport, fly to Sauce Viejo Airport
- Take the bus from Santiago to Paraíso, Panamá Provincebus
- Fly from Tocumen International Airport (PTY) to Sauce Viejo Airport (SFN)plane PTY - SFN
22h 50m$460,890–1,490,890Bus to Tocumen International Airport, fly to Buenos Aires Jorge Newbery, bus
- Take the bus from Santiago to Paraíso, Panamá Provincebus
- Fly from Tocumen International Airport (PTY) to Buenos Aires Jorge Newbery (AEP)plane PTY - AEP
- Take the bus from Avenida Costanera Rafael Obligado to Terminal de Santa Fe Gral. Belgranobus
22h 58m$622,890–1,115,890Bus to Tocumen International Airport, fly to Ministro Pistarini International Airport, bus
- Take the bus from Santiago to Paraíso, Panamá Provincebus
- Fly from Tocumen International Airport (PTY) to Ministro Pistarini International Airport (EZE)plane PTY - EZE
- Take the bus from Avenida Costanera Rafael Obligado to Terminal de Santa Fe Gral. Belgranobus
21h 40m$732,890–1,425,890
David (DAV) to Rosario – Islas Malvinas International Airport (ROS) flights
Questions & Answers
The cheapest way to get from Santiago to Santa Fe is to bus and fly which costs $410000 - $1400000 and takes 20h 39m.
The fastest way to get from Santiago to Santa Fe is to bus and fly which takes 19h 34m and costs $900000 - $1800000.
The distance between Santiago and Santa Fe is 5536 km.
It takes approximately 23h 22m to get from Santiago to Santa Fe, including transfers.
Santa Fe is 2h ahead of Santiago. It is currently 11:25 AM in Santiago and 1:25 PM in Santa Fe.
There are 579+ hotels available in Santa Fe.
What companies run services between Santiago, Panama and Santa Fe, Argentina?
There is no direct connection from Santiago to Santa Fe. However, you can take the bus to David, take the taxi to David (DAV) airport, fly to Rosario – Islas Malvinas International Airport (ROS), walk to Rosario Airport, take the bus to Cordoba y Cafferata, walk to Terminal de Rosario Mariano Moreno, then take the bus to Terminal de Santa Fe Gral. Belgrano. Alternatively, you can take the bus to Paraíso, Panamá Province, walk to Paraíso, take the shuttle to Aeropuerto Internacional de Tocumen, walk to Tocumen International Airport (PTY) airport, fly to Rosario – Islas Malvinas International Airport (ROS), walk to Rosario Airport, take the bus to Cordoba y Cafferata, walk to Terminal de Rosario Mariano Moreno, then take the bus to Terminal de Santa Fe Gral. Belgrano.
- Website
- aerolineas.com.ar
Flights from Tocumen International Airport to General Justo José De Urquiza Airport via Montevideo, Buenos Aires Jorge Newbery
- Ave. Duration
- 13h 30m
- When
- Saturday
- Estimated price
- $470,000–1,800,000
Flights from Tocumen International Airport to General Justo José De Urquiza Airport via Asuncion, Buenos Aires Jorge Newbery
- Ave. Duration
- 14h 17m
- When
- Saturday
- Estimated price
- $460,000–1,800,000
Flights from Tocumen International Airport to General Justo José De Urquiza Airport via Ingeniero Aeronáutico Ambrosio L.V. Taravella International Airport, Buenos Aires Jorge Newbery
- Ave. Duration
- 16h 47m
- When
- Monday, Tuesday, Wednesday, Thursday, Sunday, and Saturday
- Estimated price
- $450,000–1,700,000
Flights from Tocumen International Airport to General Justo José De Urquiza Airport via Rosario – Islas Malvinas International Airport, Buenos Aires Jorge Newbery
- Ave. Duration
- 16h 45m
- When
- Saturday
- Estimated price
- $450,000–1,700,000
Flights from Tocumen International Airport to General Justo José De Urquiza Airport via Tucuman, Buenos Aires Jorge Newbery
- Ave. Duration
- 20h 19m
- When
- Monday and Wednesday
- Estimated price
- $450,000–1,700,000
Flights from Tocumen International Airport to General Justo José De Urquiza Airport via Salta, Buenos Aires Jorge Newbery
- Ave. Duration
- 20h 20m
- When
- Tuesday, Thursday, and Sunday
- Estimated price
- $440,000–1,700,000
Flights from Tocumen International Airport to General Justo José De Urquiza Airport via Santa Cruz, Buenos Aires Jorge Newbery
- Ave. Duration
- 20h 20m
- When
- Monday
- Estimated price
- $450,000–1,700,000
Flights from Tocumen International Airport to Sauce Viejo Airport via Lima, Buenos Aires Jorge Newbery
- Ave. Duration
- 14h 31m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $500,000–1,800,000
Flights from Tocumen International Airport to Sauce Viejo Airport via Montevideo, Buenos Aires Jorge Newbery
- Ave. Duration
- 16h 50m
- When
- Tuesday, Wednesday, Thursday, and Sunday
- Estimated price
- $390,000–1,500,000
Flights from Tocumen International Airport to Sauce Viejo Airport via Ingeniero Aeronáutico Ambrosio L.V. Taravella International Airport, Buenos Aires Jorge Newbery
- Ave. Duration
- 17h 37m
- When
- Tuesday, Wednesday, Thursday, and Sunday
- Estimated price
- $380,000–1,500,000
Flights from Tocumen International Airport to Sauce Viejo Airport via Asuncion, Buenos Aires Jorge Newbery
- Ave. Duration
- 17h 37m
- When
- Tuesday, Wednesday, Thursday, and Sunday
- Estimated price
- $380,000–1,500,000
Flights from Tocumen International Airport to Sauce Viejo Airport via Rosario – Islas Malvinas International Airport, Buenos Aires Jorge Newbery
- Ave. Duration
- 20h 5m
- When
- Tuesday
- Estimated price
- $370,000–1,400,000
Flights from Tocumen International Airport to Sauce Viejo Airport via Tucuman, Buenos Aires Jorge Newbery
- Ave. Duration
- 22h 19m
- When
- Wednesday
- Estimated price
- $370,000–1,400,000
Flights from Tocumen International Airport to Sauce Viejo Airport via Salta, Buenos Aires Jorge Newbery
- Ave. Duration
- 22h 20m
- When
- Tuesday, Thursday, and Sunday
- Estimated price
- $370,000–1,400,000
Flights from Tocumen International Airport to Buenos Aires Jorge Newbery via Montevideo
- Ave. Duration
- 10h 30m
- When
- Every day
- Estimated price
- $290,000–1,200,000
Flights from Tocumen International Airport to Buenos Aires Jorge Newbery via Santa Cruz
- Ave. Duration
- 11h 40m
- When
- Monday and Friday
- Estimated price
- $280,000–1,100,000
Flights from Tocumen International Airport to Buenos Aires Jorge Newbery via Ingeniero Aeronáutico Ambrosio L.V. Taravella International Airport
- Ave. Duration
- 12h 8m
- When
- Monday to Saturday
- Estimated price
- $280,000–1,100,000
Flights from Tocumen International Airport to Buenos Aires Jorge Newbery via Rosario – Islas Malvinas International Airport
- Ave. Duration
- 14h 10m
- When
- Tuesday, Friday, and Saturday
- Estimated price
- $280,000–1,100,000
- Website
- latam.com
Flights from Tocumen International Airport to General Justo José De Urquiza Airport via Asuncion, Buenos Aires Jorge Newbery
- Ave. Duration
- 14h 17m
- When
- Saturday
- Estimated price
- $460,000–1,800,000
Flights from Tocumen International Airport to General Justo José De Urquiza Airport via Lima, Buenos Aires Jorge Newbery
- Ave. Duration
- 14h 21m
- When
- Saturday
- Estimated price
- $650,000–2,000,000
Flights from Tocumen International Airport to General Justo José De Urquiza Airport via Ingeniero Aeronáutico Ambrosio L.V. Taravella International Airport, Buenos Aires Jorge Newbery
- Ave. Duration
- 16h 47m
- When
- Monday, Tuesday, Wednesday, Thursday, Sunday, and Saturday
- Estimated price
- $450,000–1,700,000
Flights from Tocumen International Airport to General Justo José De Urquiza Airport via Rosario – Islas Malvinas International Airport, Buenos Aires Jorge Newbery
- Ave. Duration
- 16h 45m
- When
- Saturday
- Estimated price
- $450,000–1,700,000
Flights from Tocumen International Airport to General Justo José De Urquiza Airport via Tucuman, Buenos Aires Jorge Newbery
- Ave. Duration
- 20h 19m
- When
- Monday and Wednesday
- Estimated price
- $450,000–1,700,000
Flights from Tocumen International Airport to General Justo José De Urquiza Airport via Salta, Buenos Aires Jorge Newbery
- Ave. Duration
- 20h 20m
- When
- Tuesday, Thursday, and Sunday
- Estimated price
- $440,000–1,700,000
Flights from Tocumen International Airport to Sauce Viejo Airport via Ingeniero Aeronáutico Ambrosio L.V. Taravella International Airport, Buenos Aires Jorge Newbery
- Ave. Duration
- 17h 37m
- When
- Tuesday, Wednesday, Thursday, and Sunday
- Estimated price
- $380,000–1,500,000
Flights from Tocumen International Airport to Sauce Viejo Airport via Asuncion, Buenos Aires Jorge Newbery
- Ave. Duration
- 17h 37m
- When
- Tuesday, Wednesday, Thursday, and Sunday
- Estimated price
- $380,000–1,500,000
Flights from Tocumen International Airport to Sauce Viejo Airport via Lima, Buenos Aires Jorge Newbery
- Ave. Duration
- 17h 41m
- When
- Tuesday, Wednesday, Thursday, and Sunday
- Estimated price
- $500,000–1,600,000
Flights from Tocumen International Airport to Sauce Viejo Airport via Rosario – Islas Malvinas International Airport, Buenos Aires Jorge Newbery
- Ave. Duration
- 20h 5m
- When
- Tuesday
- Estimated price
- $370,000–1,400,000
Flights from Tocumen International Airport to Sauce Viejo Airport via Tucuman, Buenos Aires Jorge Newbery
- Ave. Duration
- 22h 19m
- When
- Wednesday
- Estimated price
- $370,000–1,400,000
Flights from Tocumen International Airport to Sauce Viejo Airport via Salta, Buenos Aires Jorge Newbery
- Ave. Duration
- 22h 20m
- When
- Tuesday, Thursday, and Sunday
- Estimated price
- $370,000–1,400,000
Flights from Tocumen International Airport to Buenos Aires Jorge Newbery via Ingeniero Aeronáutico Ambrosio L.V. Taravella International Airport
- Ave. Duration
- 12h 8m
- When
- Monday to Saturday
- Estimated price
- $280,000–1,100,000
Flights from Tocumen International Airport to Buenos Aires Jorge Newbery via Rosario – Islas Malvinas International Airport
- Ave. Duration
- 14h 10m
- When
- Tuesday, Friday, and Saturday
- Estimated price
- $280,000–1,100,000
- Website
- copaair.com
Flights from David to Rosario – Islas Malvinas International Airport via Tocumen International Airport
- Ave. Duration
- 12h 23m
- When
- Every day
- Estimated price
- $550,000–2,200,000
Flights from Tocumen International Airport to Rosario – Islas Malvinas International Airport
- Ave. Duration
- 6h 48m
- When
- Every day
- Estimated price
- $310,000–1,200,000
Flights from Tocumen International Airport to Ingeniero Aeronáutico Ambrosio L.V. Taravella International Airport
- Ave. Duration
- 6h 40m
- When
- Every day
- Estimated price
- $290,000–1,200,000
Flights from David to Ingeniero Aeronáutico Ambrosio L.V. Taravella International Airport via Tocumen International Airport
- Ave. Duration
- 11h 1m
- When
- Every day
- Estimated price
- $500,000–2,100,000
Flights from Tocumen International Airport to Ministro Pistarini International Airport
- Ave. Duration
- 7h 11m
- When
- Every day
- Estimated price
- $330,000–1,300,000
- Website
- avianca.com
Flights from Tocumen International Airport to Ingeniero Aeronáutico Ambrosio L.V. Taravella International Airport via Bogota
- Ave. Duration
- 11h 47m
- When
- Every day
- Estimated price
- $480,000–1,600,000
- Website
- flybondi.com
Flights from Tocumen International Airport to Buenos Aires Jorge Newbery via Ingeniero Aeronáutico Ambrosio L.V. Taravella International Airport
- Ave. Duration
- 9h 32m
- When
- Every day
- Estimated price
- $280,000–1,100,000
Flights from Tocumen International Airport to Buenos Aires Jorge Newbery via Asuncion
- Ave. Duration
- 12h 57m
- When
- Every day
- Estimated price
- $290,000–1,100,000
- Website
- silkwayairlines.com
Flights from Tocumen International Airport to Buenos Aires Jorge Newbery via Asuncion
- Ave. Duration
- 11h 4m
- When
- Monday, Tuesday, and Friday
- Estimated price
- $290,000–1,100,000
- Phone
- +507 775-2974
- [email protected]
- Website
- Terminales Panama David
Bus from Santiago to David
- Ave. Duration
- 2h 57m
- Frequency
- Hourly
- Schedules at
- Terminales Panama David
Bus from Santiago to Paraíso, Panamá Province
- Ave. Duration
- 3h 53m
- Frequency
- Hourly
- Estimated price
- $18,324
- Schedules at
- Terminales Panama David
Bus from Santiago to Paraíso, Panamá Province
- Ave. Duration
- 3h 53m
- Frequency
- Hourly
- Estimated price
- $18,324
- Schedules at
- Terminales Panama David
Bus from Santiago to Paraíso, Panamá Province
- Ave. Duration
- 3h 53m
- Frequency
- Hourly
- Estimated price
- $18,324
- Schedules at
- Terminales Panama David
Bus from Santiago to David
- Ave. Duration
- 2h 57m
- Frequency
- Hourly
- Schedules at
- Terminales Panama David
Bus from Santiago to Paraíso, Panamá Province
- Ave. Duration
- 3h 53m
- Frequency
- Hourly
- Estimated price
- $18,324
- Schedules at
- Terminales Panama David
Bus from Santiago to Paraíso, Panamá Province
- Ave. Duration
- 3h 53m
- Frequency
- Hourly
- Estimated price
- $18,324
- Schedules at
- Terminales Panama David
Bus from Santiago to Paraíso, Panamá Province
- Ave. Duration
- 3h 53m
- Frequency
- Hourly
- Estimated price
- $18,324
- Schedules at
- Terminales Panama David
- Phone
- +54 0810 810 9999
- [email protected]
- Website
- elpulqui.com
Bus from Terminal de Rosario Mariano Moreno to Terminal de Santa Fe Gral. Belgrano
- Ave. Duration
- 2h 20m
- Frequency
- 4 times a day
- Estimated price
- $18,000–24,000
- Schedules at
- elpulqui.com
- Book at
- reservadirecta.sittnet.net
- Semicama
- $18,000–24,000
Bus from Terminal de Rosario Mariano Moreno to Terminal de Santa Fe Gral. Belgrano
- Ave. Duration
- 2h 20m
- Frequency
- 4 times a day
- Estimated price
- $18,000–24,000
- Schedules at
- elpulqui.com
- Book at
- reservadirecta.sittnet.net
- Semicama
- $18,000–24,000
Bus from Avenida Costanera Rafael Obligado to Terminal de Santa Fe Gral. Belgrano
- Ave. Duration
- 5h 55m
- Frequency
- Once daily
- Estimated price
- $34,000–44,000
- Schedules at
- elpulqui.com
- Book at
- reservadirecta.sittnet.net
- Semicama
- $34,000–44,000
Bus from Avenida Costanera Rafael Obligado to Terminal de Santa Fe Gral. Belgrano
- Ave. Duration
- 5h 55m
- Frequency
- Once daily
- Estimated price
- $34,000–44,000
- Schedules at
- elpulqui.com
- Book at
- reservadirecta.sittnet.net
- Semicama
- $34,000–44,000
- Phone
- 0810-333-7575
- [email protected]
- Website
- viatac.com.ar
Bus from Terminal de Rosario Mariano Moreno to Terminal de Santa Fe Gral. Belgrano
- Ave. Duration
- 2h 10m
- Frequency
- Once daily
- Estimated price
- $11,000–21,000
- Schedules at
- viatac.com.ar
- Book at
- viatac.com.ar
- Semi Bed
- $11,000–18,000
- Bed
- $14,000–21,000
Bus from Terminal de Rosario Mariano Moreno to Terminal de Santa Fe Gral. Belgrano
- Ave. Duration
- 2h 10m
- Frequency
- Once daily
- Estimated price
- $11,000–21,000
- Schedules at
- viatac.com.ar
- Book at
- viatac.com.ar
- Semi Bed
- $11,000–18,000
- Bed
- $14,000–21,000
Bus from Avenida Costanera Rafael Obligado to Terminal de Santa Fe Gral. Belgrano
- Ave. Duration
- 6h 40m
- Frequency
- Twice daily
- Estimated price
- $32,000–60,000
- Schedules at
- viatac.com.ar
- Book at
- viatac.com.ar
- Semi Bed
- $32,000–48,000
- Bed
- $38,000–60,000
Bus from Avenida Costanera Rafael Obligado to Terminal de Santa Fe Gral. Belgrano
- Ave. Duration
- 6h 40m
- Frequency
- Twice daily
- Estimated price
- $32,000–60,000
- Schedules at
- viatac.com.ar
- Book at
- viatac.com.ar
- Semi Bed
- $32,000–48,000
- Bed
- $38,000–60,000
- Phone
- +54 9 11 4494 5021
- [email protected]
- Website
- Zenit
Bus from Terminal de Ómnibus Córdoba T1 to Terminal de Santa Fe Gral. Belgrano
- Ave. Duration
- 5h 10m
- Frequency
- 5 times a day
- Estimated price
- $28,000–55,000
- Schedules at
- Zenit
- Cama
- $36,000–55,000
- Semicama
- $28,000–41,000
Bus from Terminal de Ómnibus Córdoba T1 to Terminal de Santa Fe Gral. Belgrano
- Ave. Duration
- 5h 10m
- Frequency
- 5 times a day
- Estimated price
- $28,000–55,000
- Schedules at
- Zenit
- Cama
- $36,000–55,000
- Semicama
- $28,000–41,000
- Phone
- 0800-222-6513
- [email protected]
- Website
- la20.com.ar
Bus from Terminal de Ómnibus Córdoba T1 to Terminal de Santa Fe Gral. Belgrano
- Ave. Duration
- 5h 30m
- Frequency
- Once daily
- Estimated price
- $40,000–65,000
- Schedules at
- la20.com.ar
- Semicama
- $40,000–55,000
- Cama
- $49,000–65,000
Bus from Terminal de Ómnibus Córdoba T1 to Terminal de Santa Fe Gral. Belgrano
- Ave. Duration
- 5h 30m
- Frequency
- Once daily
- Estimated price
- $40,000–65,000
- Schedules at
- la20.com.ar
- Semicama
- $40,000–55,000
- Cama
- $49,000–65,000
- Phone
- +54 295 4 830086
- [email protected]
- Website
- dumascat.com.ar
Bus from Terminal de Ómnibus Córdoba T1 to Terminal de Santa Fe Gral. Belgrano
- Ave. Duration
- 5h
- Frequency
- 6 times a week
- Estimated price
- $34,000–46,000
- Schedules at
- dumascat.com.ar
- Book at
- dumascat.com.ar
- Suite
- $35,000–46,000
- Cama
- $34,000–40,000
Bus from Terminal de Ómnibus Córdoba T1 to Terminal de Santa Fe Gral. Belgrano
- Ave. Duration
- 5h
- Frequency
- 6 times a week
- Estimated price
- $34,000–46,000
- Schedules at
- dumascat.com.ar
- Book at
- dumascat.com.ar
- Suite
- $35,000–46,000
- Cama
- $34,000–40,000
- Phone
- 0810 222-5202
- [email protected]
- Website
- Flecha Bus
Bus from Avenida Costanera Rafael Obligado to Terminal de Santa Fe Gral. Belgrano
- Ave. Duration
- 5h 35m
- Frequency
- Every 4 hours
- Estimated price
- $41,000–75,000
- Website
- Flecha Bus
- Cama
- $50,000–75,000
- Semi Cama
- $41,000–60,000
Bus from Avenida Costanera Rafael Obligado to Terminal de Santa Fe Gral. Belgrano
- Ave. Duration
- 5h 35m
- Frequency
- Every 4 hours
- Estimated price
- $41,000–75,000
- Website
- Flecha Bus
- Cama
- $50,000–75,000
- Semi Cama
- $41,000–60,000
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