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How to get fromSantiago de Cuba to Cayo Santa Mariaby bus, train, or plane

Find Transport to Cayo Santa Maria

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There are 4 ways to get from Santiago de Cuba to Cayo Santa Maria by bus, train, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus via Santa Clara

    best
    1. Take the bus from Santiago de Cuba to Santa Clarabus bus Santa Clara
    2. Take the bus from Santa Clara to Cayo Santa Maríabus bus Santa Clara
    12h 30m
    $12–25
  2. Train, bus

    1. Take the train from Santiago de Cuba to Santa Claratrain train 12 / ...
    2. Take the bus from Santa Clara to Cayo Santa Maríabus bus Santa Clara
    16h 14m
    $12–27
  3. Fly, bus

    1. Fly from Antonio Maceo International Airport (SCU) to Abel Santamaría Airport (SNU)plane plane SCU - SNU
    2. Take the bus from Santa Clara to Cayo Santa Maríabus bus
    19h 43m
    $105–477
  4. Bus

    1. Take the bus from Terminal de Ómnibus Nacionales Santiago de Cuba to Santa Clarabus bus La Habana Vía Holguín / ...
    2. Take the bus from Santa Clara to Cayo Santa Maríabus bus Santa Clara
    15h 5m
    $54–81

Antonio Maceo International Airport (SCU) to Abel Santamaría Airport (SNU) flights

Calendar9Weekly Planes
Duration20h 53mAverage Duration
Ticket$84Cheapest Price
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Questions & Answers

What companies run services between Santiago de Cuba and Cayo Santa Maria, Cuba?

You can take a bus from Santiago de Cuba to Cayo Santa María via Parque, Vc, and Santa Clara in around 12h 30m.

Airlines
Train operators
Bus operators

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