Rome2Rio

How to get fromSantiago de Cuba to Isla Margaritaby plane, bus, or taxi

Find Transport to Isla Margarita

See all options

There are 5 ways to get from Santiago de Cuba to Isla Margarita by plane, bus, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Antonio Maceo International Airport to Silvio Pettirossi International Airport, bus

    best
    1. Fly from Antonio Maceo International Airport (SCU) to Silvio Pettirossi International Airport (ASU)plane plane SCU - ASU
    2. Take the bus from Terminal de Ómnibus de Asunción to La Niñabus bus
    25h 11m
    $393–1,350

  2. Bus to Ignacio Agramonte International Airport, fly to Silvio Pettirossi International Airport, bus

    cheapest
    1. Take the bus from Santiago de Cuba to Camagüeybus bus
    2. Fly from Ignacio Agramonte International Airport (CMW) to Silvio Pettirossi International Airport (ASU)plane plane CMW - ASU
    3. Take the bus from Terminal de Ómnibus de Asunción to La Niñabus bus
    25h 53m
    $383–1,352

  3. Fly Antonio Maceo International Airport to Foz Do Iguaçu / Cataratas International Airport, bus, taxi

    1. Fly from Antonio Maceo International Airport (SCU) to Foz Do Iguaçu / Cataratas International Airport (IGU)plane plane SCU - IGU
    2. Take the bus from Terminal de Ómnibus de Ciudad del Este to Coronel Oviedobus bus
    3. Take the bus from Coronel Oviedo to San Pedro de Ycuamandiyúbus bus
    4. Take the taxi from San Pedro de Ycuamandiyú to Isla Margaritataxi taxi
    34h 55m
    $471–13,653

  4. Bus to Frank País International Airport, fly to Silvio Pettirossi International Airport, bus

    1. Take the bus from Terminal de Ómnibus Nacionales Santiago de Cuba to Holguin Airportbus bus
    2. Fly from Frank País International Airport (HOG) to Silvio Pettirossi International Airport (ASU)plane plane HOG - ASU
    3. Take the bus from Terminal de Ómnibus de Asunción to La Niñabus bus
    25h 29m
    $395–1,369

  5. Bus to Frank País International Airport, fly to Foz Do Iguaçu / Cataratas International Airport, bus, taxi

    1. Take the bus from Terminal de Ómnibus Nacionales Santiago de Cuba to Holguin Airportbus bus
    2. Fly from Frank País International Airport (HOG) to Foz Do Iguaçu / Cataratas International Airport (IGU)plane plane HOG - IGU
    3. Take the bus from Terminal de Ómnibus de Ciudad del Este to Coronel Oviedobus bus
    4. Take the bus from Coronel Oviedo to San Pedro de Ycuamandiyúbus bus
    5. Take the taxi from San Pedro de Ycuamandiyú to Isla Margaritataxi taxi
    34h 13m
    $433–13,472

Antonio Maceo International Airport (SCU) to Silvio Pettirossi International Airport (ASU) flights

Calendar4Weekly Planes
Duration24h 4mAverage Duration
Ticket$356Cheapest Price
See schedules

Questions & Answers

Map of how to get from Santiago de Cuba to Isla Margarita.ExpandLaunch map view
  • Distance: 5,713.9 km
  • Duration: 25h 11m

What companies run services between Santiago de Cuba and Isla Margarita, Paraguay?

There is no direct connection from Santiago de Cuba to Isla Margarita. However, you can take the bus to Santiago Airport, walk to Antonio Maceo International Airport (SCU) airport, fly to Silvio Pettirossi International Airport (ASU), take the taxi to Terminal de Ómnibus de Asunción, take the bus to La Niña, then take the taxi to Isla Margarita. Alternatively, you can take the bus to Santiago Airport, walk to Antonio Maceo International Airport (SCU) airport, fly to Foz Do Iguaçu / Cataratas International Airport (IGU), walk to Foz do Iguaçu Airport - IGU, take the line 120 bus to Terminal de Transportes Urbano - Foz do Iguaçu, take the bus to Terminal de Omnibus de Ciudad del Este, take the bus to Coronel Oviedo, take the bus to San Pedro de Ycuamandiyú, then take the taxi to Isla Margarita.

Airlines
Bus operators
Other operators

Want to know more about travelling around the world?

Rome2Rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including How to get from Stansted Airport into central London, Travelling around the UAE, and Need to know: Eurostar - to help you get the most out of your next trip.