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How to get fromSantiago de Cuba to St. Louisby plane or bus

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There are 2 ways to get from Santiago de Cuba to St. Louis by plane or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Antonio Maceo International Airport

    best
    1. Fly from Antonio Maceo International Airport (SCU) to Lambert–St. Louis International Airport (STL)plane plane SCU - STL
    12h 45m
    $197–857

  2. Bus to Frank País International Airport, fly

    1. Take the bus from Terminal de Ómnibus Nacionales Santiago de Cuba to Holguin Airportbus bus
    2. Fly from Frank País International Airport (HOG) to Lambert–St. Louis International Airport (STL)plane plane HOG - STL
    12h 3m
    $199–825

Antonio Maceo International Airport (SCU) to Lambert–St. Louis International Airport (STL) flights

Calendar6Weekly Planes
Duration11h 5mAverage Duration
Ticket$198Cheapest Price
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Questions & Answers

Map of how to get from Santiago de Cuba to St. Louis.ExpandLaunch map view
  • Distance: 1,578.7 mi
  • Duration: 12h 45m

What companies run services between Santiago de Cuba and St. Louis, MO, USA?

American Airlines and Southwest Airlines fly from Antonio Maceo International Airport (SCU) to Lambert–St. Louis International Airport (STL) 6 times a week.

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