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How to get fromSantiago del Estero to Uyuniby bus, shuttle, car, plane, or train

Find Transport to Uyuni

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There are 8 ways to get from Santiago del Estero to Uyuni by bus, shuttle, car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, Tour

    best
    1. Take the bus from Terminal de Ómnibus de Santiago del Estero to Terminal de Saltabus bus
    2. Take a shuttle bus from Salta to Uyunishuttle bus Salta
    11h 57m
    $323–345
  2. Bus, train

    cheapest
    1. Take the bus from Terminal de Ómnibus de Santiago del Estero to Terminal La Quiacabus bus
    2. Take the train from Villazón to Uyunítrain train Expreso del Sur
    24h 9m
    $38–64
  3. Drive 1,024.8 km

    1. Drive from Santiago del Estero to Uyunicar car 1,024.8 km
    12h 22m
    $92–132
  4. Fly to Uyuni Airport

    1. Fly from Vicecomodoro Ángel De La Paz Aragonés Airport (SDE) to Uyuni Airport (UYU)plane plane SDE - UYU
    15h 46m
    $612–2,115
  5. Bus

    1. Take the bus from Terminal de Ómnibus de Santiago del Estero to Terminal La Quiacabus bus
    2. Take the bus from Villazón to Uyunibus bus Uyuni
    19h 40m
    $40–62
  6. Bus via Uyuni

    1. Take the bus from Terminal de Ómnibus de Santiago del Estero to Terminal La Quiacabus bus
    2. Take the bus from Villazón to Uyunibus bus Villazón
    21h 31m
    $43–57
  7. Fly to Gobernador Horacio Guzmán International Airport, bus, Tour

    1. Fly from Vicecomodoro Ángel De La Paz Aragonés Airport (SDE) to Gobernador Horacio Guzmán International Airport (JUJ)plane plane SDE - JUJ
    2. Take the bus from Terminal de Omnibus de General Guemes to Terminal de Saltabus bus
    3. Take a shuttle bus from Salta to Uyunishuttle bus
    15h 17m
    $534–777
  8. Fly to Alcantari Airport, bus

    1. Fly from Vicecomodoro Ángel De La Paz Aragonés Airport (SDE) to Alcantari Airport (SRE)plane plane SDE - SRE
    2. Take the bus from Sucre to Uyunibus bus
    21h 31m
    $426–1,365

Vicecomodoro Ángel De La Paz Aragonés Airport (SDE) to Uyuni Airport (UYU) flights

Calendar4Weekly Planes
Duration19h 33mAverage Duration
Ticket$628Cheapest Price
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Questions & Answers

What companies run services between Santiago del Estero, Argentina and Uyuni, Potosí, Bolivia?

Aerolíneas Argentinas, Boliviana de Aviación, and Eco Jet fly from Vicecomodoro Ángel De La Paz Aragonés Airport (SDE) to Uyuni Airport (UYU) 4 times a week. Alternatively, you can take a bus from Terminal de Ómnibus de Santiago del Estero to Uyuni via Terminal La Quiaca and Villazón in around 19h 40m.

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