There are 5 ways to get from Santiago to Antioquia by plane, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Medellin Jose Marie Cordova
best- Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Medellin Jose Marie Cordova (MDE)plane SCL - MDE
9h 39m$177–572Bus
- Take the bus from Terminal San Borja to Rumichacabus
- Take the bus from Terminales de Transportes de Ipiales to Terminal Salitrebus
- Take the bus from Terminal Salitre to Terminal del Nortebus
4d 10h$413–588Drive 6,121.4 km
- Drive from Santiago to Medellíncar 6,121.4 km
3d 12h$755–1,091Fly to Enrique Olaya Herrera Airport
- Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Enrique Olaya Herrera Airport (EOH)plane SCL - EOH
11h 34m$383–1,403Bus via Lima
- Take the bus from Terminal Sur de Santiago to Lima Javier Pradobus
- Take the bus from Lima Javier Prado to Terminal Terrestre Quitumbebus
- Take the bus from Terminal Terrestre Quitumbe to Lago Agríobus
- Take the bus from La Dorada, Putumayo to Terminal del Nortebus
5d 1h$237–391
Comodoro Arturo Merino Benítez International Airport (SCL) to Medellin Jose Marie Cordova (MDE) flights
Questions & Answers
The cheapest way to get from Santiago to Antioquia is to fly which costs $170 - $600 and takes 9h 39m.
The fastest way to get from Santiago to Antioquia is to fly which takes 9h 39m and costs $170 - $600.
No, there is no direct bus from Santiago to Antioquia. However, there are services departing from Terminal San Borja and arriving at Terminal del Norte via Rumichaca, Terminales de Transportes de Ipiales and Terminal Salitre. The journey, including transfers, takes approximately 4 days 10h.
The distance between Santiago and Antioquia is 4464 km. The road distance is 6121.4 km.
The best way to get from Santiago to Antioquia without a car is to bus which takes 4 days 10h and costs $410 - $600.
It takes approximately 9h 39m to get from Santiago to Antioquia, including transfers.
Santiago to Antioquia bus services, operated by Lineas de Los Andes, depart from Terminal San Borja station.
The best way to get from Santiago to Antioquia is to fly which takes 9h 39m and costs $170 - $600. Alternatively, you can bus, which costs $410 - $600 and takes 4 days 10h.
Santiago to Antioquia bus services, operated by Lineas de Los Andes, arrive at Rumichaca station.
Antioquia is 1h behind Santiago. It is currently 12:12 PM in Santiago and 11:12 AM in Antioquia.
What companies run services between Santiago, Chile and Antioquia, Colombia?
JetSMART, Avianca - Aerovías del Continente Americano S.A., and two other airlines fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Medellin Jose Marie Cordova (MDE) every 2 hours. Alternatively, you can take a bus from Terminal San Borja to Parque Berrio Cra.52 #50-70 Medellin via Rumichaca, Terminal Ipiales, Terminales de Transportes de Ipiales, Terminal Salitre, Terminal del Norte, and Caribe Cra.64 # 75b-400 Medellin in around 4d 10h.
- Website
- avianca.com
Flights from Comodoro Arturo Merino Benítez International Airport to Medellin Jose Marie Cordova via Bogota
- Ave. Duration
- 8h
- When
- Every day
- Estimated price
- $220–750
Flights from Comodoro Arturo Merino Benítez International Airport to Enrique Olaya Herrera Airport via Bogota
- Ave. Duration
- 9h 47m
- When
- Every day
- Estimated price
- $500–1,800
- Website
- copaair.com
Flights from Comodoro Arturo Merino Benítez International Airport to Medellin Jose Marie Cordova via Panama City
- Ave. Duration
- 9h 52m
- When
- Every day
- Estimated price
- $150–600
- Website
- jetsmart.com
Flights from Comodoro Arturo Merino Benítez International Airport to Medellin Jose Marie Cordova
- Ave. Duration
- 6h 24m
- When
- Monday, Tuesday, Friday, and Saturday
- Estimated price
- $140–430
Flights from Comodoro Arturo Merino Benítez International Airport to Medellin Jose Marie Cordova via Cali
- Ave. Duration
- 8h 45m
- When
- Sunday
- Estimated price
- $140–430
Flights from Comodoro Arturo Merino Benítez International Airport to Medellin Jose Marie Cordova via Bogota
- Ave. Duration
- 10h 53m
- When
- Thursday, Friday, and Sunday
- Estimated price
- $140–430
- Website
- latam.com
Flights from Comodoro Arturo Merino Benítez International Airport to Medellin Jose Marie Cordova via Bogota
- Ave. Duration
- 8h 55m
- When
- Every day
- Estimated price
- $190–500
Flights from Comodoro Arturo Merino Benítez International Airport to Medellin Jose Marie Cordova via Lima
- Ave. Duration
- 9h 30m
- When
- Every day
- Estimated price
- $190–500
- Website
- easyfly.com.co
Flights from Comodoro Arturo Merino Benítez International Airport to Enrique Olaya Herrera Airport via Bogota
- Ave. Duration
- 8h 30m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $460–1,500
Flights from Comodoro Arturo Merino Benítez International Airport to Enrique Olaya Herrera Airport via Panama City, Pereira
- Ave. Duration
- 11h 46m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $380–1,400
- Phone
- +51 9 6788 4526
- [email protected]
- Website
- Lineas De Los Andes
Bus from Terminal San Borja to Rumichaca
- Ave. Duration
- 2d 23h
- Frequency
- Once daily
- Estimated price
- $330–460
- Website
- Lineas De Los Andes
- Phone
- +57 601 424 9090
- [email protected]
- Website
- continentalbus.com.co
Bus from Terminales de Transportes de Ipiales to Terminal Salitre
- Ave. Duration
- 22h
- Frequency
- Every 4 hours
- Estimated price
- $61
- Schedules at
- continentalbus.com.co
- Phone
- +57 601 4249090
- [email protected]
- Website
- bolivariano.com.co
Bus from Terminales de Transportes de Ipiales to Terminal Salitre
- Ave. Duration
- 22h
- Frequency
- Every 4 hours
- Estimated price
- $45–85
- Schedules at
- bolivariano.com.co
- Book at
- bolivariano.com.co
Bus from Terminal Salitre to Terminal del Norte
- Ave. Duration
- 10h
- Frequency
- Every 3 hours
- Estimated price
- $28–40
- Schedules at
- bolivariano.com.co
- Book at
- bolivariano.com.co
- Phone
- +51 1 311-5050
- Website
- Cruz Del Sur International
Bus from Terminal Sur de Santiago to Lima Javier Prado
- Ave. Duration
- 2d 6h
- Frequency
- Once daily
- Estimated price
- $95–170
- Website
- Cruz Del Sur International
Bus from Lima Javier Prado to Terminal Terrestre Quitumbe
- Ave. Duration
- 35h 35m
- Frequency
- Once a week
- Estimated price
- $55–100
- Website
- Cruz Del Sur International
- Phone
- +593 98 076 1302
- [email protected]
- Website
- Expreso Baños
Bus from Terminal Terrestre Quitumbe to Lago Agrío
- Ave. Duration
- 5h 55m
- Frequency
- Every 2 hours
- Estimated price
- $11–16
- Schedules at
- Expreso Baños
Bus from Terminal Terrestre Quitumbe to Lago Agrío
- Ave. Duration
- 7h
- Frequency
- Hourly
- Estimated price
- $12–18
- Schedules at
- BAÑOS Cooperativa De Transportes y Turismo
- Phone
- +593 98 809 8584
- [email protected]
- Website
- facebook.com
Bus from Terminal Terrestre Quitumbe to Lago Agrío
- Ave. Duration
- 7h
- Frequency
- Every 4 hours
- Estimated price
- $11–14
- Schedules at
- facebook.com
- Book at
- viajabus.com
- Phone
- +593 96 297 2979
- [email protected]
- Website
- Trans Esmeraldas S.A.
Bus from Terminal Terrestre Quitumbe to Lago Agrío
- Ave. Duration
- 5h 38m
- Frequency
- Once daily
- Estimated price
- $14–20
- Schedules at
- Trans Esmeraldas S.A.
- Phone
- +59 07 257 1861
- [email protected]
- Website
- cooperativaloja.com.ec
Bus from Terminal Terrestre Quitumbe to Lago Agrío
- Ave. Duration
- 7h 5m
- Frequency
- Once daily
- Estimated price
- $10–15
- Book at
- api.whatsapp.com
- Phone
- 01-8000-910293
- [email protected]
- Website
- coomotor.com.co
Bus from La Dorada, Putumayo to Terminal del Norte
- Ave. Duration
- 22h 45m
- Frequency
- Twice daily
- Estimated price
- $70–100
- Schedules at
- coomotor.com.co
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More Questions & Answers
Yes, the driving distance between Santiago to Antioquia is 6121 km. It takes approximately 3 days 12h to drive from Santiago to Antioquia.
There are 2880+ hotels available in Antioquia.

























