There are 5 ways to get from Santiago to Antofagasta by plane, bus (Flixbus), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Antofagasta Airport (ANF)plane SCL - ANF
3h 55m$60–210Bus
cheapest- Take the bus from Terminal San Borja to Terminal de Buses Cardenal Carlos Oviedo Cavadabus Calama / ...
18h 42m$30–110Bus via Maipu esq. Avenida Argentina (Flixbus)
- Take the bus from Santiago to Antofagastabus FlixBus CL071 / ...
18h 3m$141–234Drive 1,317 km
- Drive from Santiago to Antofagastacar 1,317 km
15h 38m$163–235Bus via Pajaritos Dirección Los Domínicos
- Take the bus from Terminal Alameda - Turbus to Terminal de Buses Cardenal Carlos Oviedo Cavadabus Santiago / ...
22h 13m$32–83
Santiago to Antofagasta by bus (Flixbus)
Questions & Answers
The cheapest way to get from Santiago to Antofagasta is to bus which costs $30 - $110 and takes 18h 42m.
The fastest way to get from Santiago to Antofagasta is to fly which takes 3h 55m and costs $60 - $210.
Yes, there is a direct bus departing from Terminal San Borja and arriving at Terminal de Buses Cardenal Carlos Oviedo Cavada. Services depart hourly, and operate every day. The journey takes approximately 18h 42m.
The distance between Santiago and Antofagasta is 1146 km. The road distance is 1317 km.
The best way to get from Santiago to Antofagasta without a car is to bus via Maipu esq. Avenida Argentina which takes 18h 3m and costs $140 - $240.
It takes approximately 3h 55m to get from Santiago to Antofagasta, including transfers.
Santiago to Antofagasta bus services, operated by Flixbus Chile, depart from Santiago station.
The best way to get from Santiago to Antofagasta is to fly which takes 3h 55m and costs $60 - $210. Alternatively, you can bus via Maipu esq. Avenida Argentina, which costs $140 - $240 and takes 18h 3m.
Santiago to Antofagasta bus services, operated by Flixbus Chile, arrive at Antofagasta station.
Yes, the driving distance between Santiago to Antofagasta is 1317 km. It takes approximately 15h 38m to drive from Santiago to Antofagasta.
What companies run services between Santiago, Chile and Antofagasta, Chile?
JetSMART, Sky Airline, and LATAM Chile fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Antofagasta Airport (ANF) hourly. Alternatively, Flixbus Chile operates a bus from Santiago to Antofagasta 5 times a day. Tickets cost $140–240 and the journey takes 17h 45m.
- Website
- latam.com
Flights from Comodoro Arturo Merino Benítez International Airport to Antofagasta Airport
- Ave. Duration
- 2h 3m
- When
- Every day
- Estimated price
- $60–250
- Website
- skyairline.com
Flights from Comodoro Arturo Merino Benítez International Airport to Antofagasta Airport
- Ave. Duration
- 2h 2m
- When
- Every day
- Estimated price
- $40–180
- Website
- jetsmart.com
Flights from Comodoro Arturo Merino Benítez International Airport to Antofagasta Airport
- Ave. Duration
- 2h 4m
- When
- Every day
- Estimated price
- $30–140
- Website
- https://www.flixbus.cl/
Bus from Santiago to Antofagasta
- Ave. Duration
- 17h 45m
- Frequency
- 5 times a day
- Estimated price
- $140–240
- Schedules at
- flixbus.cl
- Phone
- +56 22 3813 550
- [email protected]
- Website
- plusschile.cl
Bus from Terminal San Borja to Terminal de Buses Cardenal Carlos Oviedo Cavada
- Ave. Duration
- 18h 42m
- Frequency
- Twice daily
- Estimated price
- $30–50
- Book at
- https://www.recorrido.cl/pluss-chile/en
- Semi Cama
- $30–40
- Cama
- $45–50
- [email protected]
- Website
- ciktur.cl
Bus from Terminal San Borja to Terminal de Buses Cardenal Carlos Oviedo Cavada
- Ave. Duration
- 17h 55m
- Frequency
- 6 times a week
- Estimated price
- $35–65
- Schedules at
- kupos.cl
- Cama
- $55–65
- Semi Cama
- $50–65
- [email protected]
- Website
- pullmansanandres.cl
Bus from Terminal San Borja to Terminal de Buses Cardenal Carlos Oviedo Cavada
- Ave. Duration
- 18h 30m
- Frequency
- Hourly
- Estimated price
- $65–110
- Schedules at
- pullmansanandres.cl
- Semi Cama
- $65–90
- Cama
- $75–110
- Phone
- +56 600 600 0018
- [email protected]
- Website
- pullmanbus.cl
Bus from Terminal San Borja to Terminal de Buses Cardenal Carlos Oviedo Cavada
- Ave. Duration
- 19h
- Frequency
- Every 4 hours
- Estimated price
- $52–64
- Schedules at
- pullmanbus.cl
- Book at
- pullmanbus.cl
- Salón Cama
- $52–57
- Phone
- +56 22 822 7500
- [email protected]
- Website
- turbus.cl
Bus from Terminal San Borja to Terminal de Buses Cardenal Carlos Oviedo Cavada
- Ave. Duration
- 20h 50m
- Frequency
- 5 times a day
- Estimated price
- $30–85
- Schedules at
- turbus.cl
- Book at
- turbus.cl
- Semi Cama
- $30–50
- Cama
- $55–80
- Premium
- $65–85
Bus from Terminal Alameda - Turbus to Terminal de Buses Cardenal Carlos Oviedo Cavada
- Ave. Duration
- 20h 50m
- Frequency
- Every 4 hours
- Estimated price
- $30–80
- Schedules at
- turbus.cl
- Book at
- turbus.cl
- Semi Cama
- $30–50
- Cama
- $55–75
- Premium
- $65–80
- Phone
- +56 9 5869 8737
- Website
- kupos.cl
Bus from Terminal San Borja to Terminal de Buses Cardenal Carlos Oviedo Cavada
- Ave. Duration
- 18h 23m
- Frequency
- Once daily
- Estimated price
- $35–50
- Website
- https://kupos.cl/es/pasajes/bus/buses-horizonte
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