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How to get fromSantiago to Antofagasta Regionby plane, bus (Flixbus), car, or bus

Find Transport to Antofagasta Region

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There are 6 ways to get from Santiago to Antofagasta Region by plane, bus (Flixbus), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Antofagasta Airport

    best
    1. Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Antofagasta Airport (ANF)plane plane SCL - ANF
    3h 27m
    $37–182
  2. Bus via Terminal San Borja

    cheapest
    1. Take the bus from Terminal San Borja to Terminal de Buses Cardenal Carlos Oviedo Cavadabus bus Calama / ...
    19h
    $31–102
  3. Bus (Flixbus)

    1. Take the bus from Santiago to Antofagastabus bus FlixBus CL071 / ...
    18h 3m
    $139–230
  4. Drive 1,317 km

    1. Drive from Santiago to Antofagastacar car 1,317 km
    15h 38m
    $163–235
  5. Fly to Calama Airport

    1. Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Calama Airport (CJC)plane plane SCL - CJC
    4h 24m
    $49–179
  6. Bus via Pajaritos Dirección Los Domínicos

    1. Take the bus from Terminal Alameda - Turbus to Terminal de Buses Cardenal Carlos Oviedo Cavadabus bus Santiago / ...
    22h 13m
    $32–83

Santiago to Antofagasta Region by bus (Flixbus)

Calendar32Weekly Buses
Duration18h 3mAverage Duration
Ticket$139Cheapest Price
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Questions & Answers

What companies run services between Santiago, Chile and Antofagasta Region, Chile?

JetSMART, Sky Airline, and LATAM Chile fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Antofagasta Airport (ANF) hourly. Alternatively, Flixbus Chile operates a bus from Santiago to Antofagasta 5 times a day. Tickets cost $130–230 and the journey takes 17h 45m.

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Bus operators

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