There are 5 ways to get from Santiago to Arequipa by plane, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Rodríguez Ballón International Airport (AQP)plane SCL - AQP
9h 25m$160–413Bus via Terminal San Borja
cheapest- Take the bus from Terminal San Borja to Terminal Rodoviario de Aricabus
- Take the bus from Terminal Internacional to Tacnabus
- Take the bus from Tacna to Arequipabus
35h 6m$65–137Bus
- Take the bus from Terminal San Borja to Terminal Rodoviario de Aricabus
- Take the bus from Terminal Internacional to Tacnabus
- Take the bus from Tacna to Arequipabus
34h 36m$86–165Drive 2,401.3 km
- Drive from Santiago to Arequipacar 2,401.3 km
29h 58m$361–522Bus via Oruro Airport (ORU)
- Take the bus from Terminal Alameda - Turbus to Orurobus
- Take the bus from Oruro to La Pazbus
- Take the bus from La Paz to Arequipabus
2d 4h$106–116
Santiago to Arequipa by bus
Questions & Answers
The cheapest way to get from Santiago to Arequipa is to bus via Terminal San Borja which costs $60 - $140 and takes 35h 6m.
The fastest way to get from Santiago to Arequipa is to fly which takes 9h 25m and costs $160 - $420.
No, there is no direct bus from Santiago to Arequipa. However, there are services departing from Terminal San Borja and arriving at Arequipa via Terminal Internacional and Tacna. The journey, including transfers, takes approximately 34h 36m.
The distance between Santiago and Arequipa is 1921 km. The road distance is 2401.3 km.
The best way to get from Santiago to Arequipa without a car is to bus which takes 34h 36m and costs $85 - $170.
It takes approximately 9h 25m to get from Santiago to Arequipa, including transfers.
Santiago to Arequipa bus services, operated by Pullman San Andres, depart from Terminal San Borja station.
The best way to get from Santiago to Arequipa is to fly which takes 9h 25m and costs $160 - $420. Alternatively, you can bus, which costs $85 - $170 and takes 34h 36m.
Santiago to Arequipa bus services, operated by Pullman San Andres, arrive at Terminal Rodoviario de Arica station.
Arequipa is 1h behind Santiago. It is currently 12:42 PM in Santiago and 11:42 AM in Arequipa.
What companies run services between Santiago, Chile and Arequipa, Peru?
LATAM Chile, JetSMART, and Sky Airline fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Rodríguez Ballón International Airport (AQP) every 4 hours. Alternatively, you can take a bus from Terminal San Borja to Arequipa via Terminal Rodoviario de Arica, Terminal Internacional, and Tacna in around 34h 36m.
- Website
- latam.com
Flights from Comodoro Arturo Merino Benítez International Airport to Rodríguez Ballón International Airport via Lima
- Ave. Duration
- 7h 26m
- When
- Every day
- Estimated price
- $170–330
Flights from Comodoro Arturo Merino Benítez International Airport to Rodríguez Ballón International Airport via Cuzco
- Ave. Duration
- 11h 35m
- When
- Monday and Friday
- Estimated price
- $170–330
- Website
- skyairline.com
Flights from Comodoro Arturo Merino Benítez International Airport to Rodríguez Ballón International Airport via Lima
- Ave. Duration
- 9h 10m
- When
- Every day
- Estimated price
- $140–450
- Website
- jetsmart.com
Flights from Comodoro Arturo Merino Benítez International Airport to Rodríguez Ballón International Airport via Lima
- Ave. Duration
- 6h 46m
- When
- Monday, Tuesday, Wednesday, Saturday, and Sunday
- Estimated price
- $150–330
- [email protected]
- Website
- pullmansanandres.cl
Bus from Terminal San Borja to Terminal Rodoviario de Arica
- Ave. Duration
- 29h 55m
- Frequency
- Hourly
- Estimated price
- $90–140
- Schedules at
- pullmansanandres.cl
- Semi Cama
- $90–130
- Cama
- $100–140
- Phone
- +56 600 600 0018
- [email protected]
- Website
- pullmanbus.cl
Bus from Terminal San Borja to Terminal Rodoviario de Arica
- Ave. Duration
- 29h 5m
- Frequency
- 5 times a day
- Estimated price
- $60–85
- Schedules at
- pullmanbus.cl
- Book at
- pullmanbus.cl
- Salón Cama
- $60–85
- Phone
- +56 58 222 8603
- [email protected]
- Website
- recorrido.cl
Bus from Terminal Internacional to Tacna
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- $5
- Website
- https://www.recorrido.cl/en/bus/buses-norte-grande-tickets
Bus from Terminal Internacional to Tacna
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- $5
- Website
- https://www.recorrido.cl/en/bus/buses-norte-grande-tickets
- Phone
- +51 953 954 708
- [email protected]
- Website
- redbus.pe
Bus from Tacna to Arequipa
- Ave. Duration
- 2h 15m
- Frequency
- Every 3 hours
- Estimated price
- $18
- Schedules at
- redbus.pe
Bus from Tacna to Arequipa
- Ave. Duration
- 2h 15m
- Frequency
- Every 3 hours
- Estimated price
- $18
- Schedules at
- redbus.pe
- Phone
- +51 982 803 213
- [email protected]
- Website
- heroesdelpacifico.embarcar.com.pe
Bus from Tacna to Arequipa
- Ave. Duration
- 5h
- Frequency
- Once daily
- Estimated price
- $18
- Schedules at
- heroesdelpacifico.embarcar.com.pe
Bus from Tacna to Arequipa
- Ave. Duration
- 5h
- Frequency
- Once daily
- Estimated price
- $18
- Schedules at
- heroesdelpacifico.embarcar.com.pe
- [email protected]
- Website
- hallpa.pe
Bus from Tacna to Arequipa
- Ave. Duration
- 6h
- Frequency
- Once daily
- Estimated price
- $21
- Schedules at
- hallpa.pe
Bus from Tacna to Arequipa
- Ave. Duration
- 6h
- Frequency
- Once daily
- Estimated price
- $21
- Schedules at
- hallpa.pe
- Phone
- +56 22 822 7500
- [email protected]
- Website
- turbus.cl
Bus from Terminal San Borja to Terminal Rodoviario de Arica
- Ave. Duration
- 30h 25m
- Frequency
- 4 times a day
- Estimated price
- $45–120
- Schedules at
- turbus.cl
- Book at
- turbus.cl
- Semi Cama
- $45–70
- Cama
- $80–120
- Premium
- $70–90
- Phone
- +56 22 3813 550
- [email protected]
- Website
- plusschile.cl
Bus from Terminal San Borja to Terminal Rodoviario de Arica
- Ave. Duration
- 29h 5m
- Frequency
- Twice daily
- Estimated price
- $40–75
- Book at
- https://www.recorrido.cl/pluss-chile/en
- Semi Cama
- $40–55
- Cama
- $65–75
- Phone
- +56 9 5869 8737
- Website
- kupos.cl
Bus from Terminal San Borja to Terminal Rodoviario de Arica
- Ave. Duration
- 28h
- Frequency
- Once daily
- Estimated price
- $50–75
- Website
- https://kupos.cl/es/pasajes/bus/buses-horizonte
- Phone
- +56 57 226 9210
- [email protected]
- Website
- busesramoscholele.cl
Bus from Terminal San Borja to Terminal Rodoviario de Arica
- Ave. Duration
- 28h 45m
- Frequency
- Once daily
- Estimated price
- $40–60
- Schedules at
- busesramoscholele.cl
- Semi cama
- $40–60
- Salón cama
- $51–55
- Phone
- +591 2527 7355
- [email protected]
- Website
- facebook.com
Bus from Terminal Alameda - Turbus to Oruro
- Ave. Duration
- 33h 2m
- Frequency
- 4 times a week
- Estimated price
- $43
- Schedules at
- facebook.com
- Phone
- +59 128 1779
- [email protected]
- Website
- facebook.com
Bus from Oruro to La Paz
- Ave. Duration
- 4h 30m
- Frequency
- Once daily
- Website
- https://boliviatravelsite.com/predilecto-bus
- Phone
- +591 466-60443
- [email protected]
- Website
- facebook.com
Bus from Oruro to La Paz
- Ave. Duration
- 5h 6m
- Frequency
- Once daily
- Estimated price
- $13–23
- Schedules at
- facebook.com
- Phone
- +591 2 228 1920
- [email protected]
- Website
- facebook.com
Bus from La Paz to Arequipa
- Ave. Duration
- 12h
- Frequency
- Once daily
- Estimated price
- $26
- Schedules at
- redbus.pe
- Phone
- +591 2245 8945
- [email protected]
- Website
- vicuna-travel.com
Bus from La Paz to Arequipa
- Ave. Duration
- 12h
- Frequency
- Once daily
- Estimated price
- $49
- Schedules at
- ticketsbolivia.com.bo
- Book at
- ticketsbolivia.com.bo
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More Questions & Answers
Yes, the driving distance between Santiago to Arequipa is 2401 km. It takes approximately 29h 58m to drive from Santiago to Arequipa.
There are 480+ hotels available in Arequipa.





































