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How to get fromSantiago to Cayo Santa Maríaby plane or bus

Find Transport to Cayo Santa María

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There are 2 ways to get from Santiago to Cayo Santa María by plane or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Abel Santamaría Airport, bus

    best
    1. Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Abel Santamaría Airport (SNU)plane plane SCL - SNU
    2. Take the bus from Santa Clara to Cayo Santa Maríabus bus
    18h 51m
    $263–935

  2. Fly to Juan Gualberto Gómez International Airport, bus

    1. Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Juan Gualberto Gómez International Airport (VRA)plane plane SCL - VRA
    2. Take the bus from Varadero Airport to Santa Clarabus bus
    3. Take the bus from Santa Clara to Cayo Santa Maríabus bus
    22h 34m
    $267–944

Comodoro Arturo Merino Benítez International Airport (SCL) to Abel Santamaría Airport (SNU) flights

Calendar30Weekly Planes
Duration14h 29mAverage Duration
Ticket$245Cheapest Price
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Questions & Answers

Map of how to get from Santiago to Cayo Santa María.ExpandLaunch map view
  • Distance: 6,432.2 km
  • Duration: 18h 51m

What companies run services between Santiago, Chile and Cayo Santa María, Villa Clara, Cuba?

There is no direct connection from Santiago to Cayo Santa María. However, you can take the bus to Estación de Buses Aeropuerto Internacional Arturo Merino Benítez, walk to Comodoro Arturo Merino Benítez International Airport (SCL) airport, fly to Abel Santamaría Airport (SNU), take the taxi to Santa Clara, then take the bus to Cayo Santa María. Alternatively, you can take the bus to Estación de Buses Aeropuerto Internacional Arturo Merino Benítez, walk to Comodoro Arturo Merino Benítez International Airport (SCL) airport, fly to Juan Gualberto Gómez International Airport (VRA), walk to Varadero Airport, take the bus to Santa Clara, then take the bus to Cayo Santa María.

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