There are 6 ways to get from Santiago to Cuenca by plane, bus, car, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Cuenca
best- Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Cuenca (CUE)plane SCL - CUE
9h 54m$242–652Bus
cheapest- Take the bus from Terminal Sur de Santiago to Lima Javier Pradobus
- Take the bus from Lima Javier Prado to Terminal Terrestre de Guayaquilbus
- Take the bus from Terminal Terrestre de Guayaquil to Cuencabus
3d 10h$152–323Bus via Piura
- Take the bus from Terminal San Borja to Gran Terminal Terrestre Plaza Nortebus
- Take the bus from Gran Terminal Terrestre Plaza Norte to Piurabus
- Take the bus from Terminal de Piura to Terminal de Cuencabus
2d 21h$280–348Drive 4,692 km
- Drive from Santiago to Cuencacar 4,692 km
2d 14h$579–836Fly to Tumbes, bus
- Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Tumbes (TBP)plane SCL - TBP
- Take the bus from Huaquillas to Cuencabus
13h 43m$183–626Fly to José Joaquín De Olmedo International Airport, taxi
- Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to José Joaquín De Olmedo International Airport (GYE)plane SCL - GYE
- Take the taxi from Guayaquil-Airport-GYE to Cuencataxi
10h 47m$342–692
Comodoro Arturo Merino Benítez International Airport (SCL) to Cuenca (CUE) flights
Questions & Answers
The cheapest way to get from Santiago to Cuenca is to bus which costs $150 - $330 and takes 3 days 10h.
The fastest way to get from Santiago to Cuenca is to fly which takes 9h 54m and costs $240 - $650.
No, there is no direct bus from Santiago to Cuenca. However, there are services departing from Terminal San Borja and arriving at Terminal de Cuenca via Gran Terminal Terrestre Plaza Norte and Terminal de Piura. The journey, including transfers, takes approximately 2 days 21h.
The distance between Santiago and Cuenca is 3511 km. The road distance is 4692 km.
The best way to get from Santiago to Cuenca without a car is to bus via Piura which takes 2 days 21h and costs $280 - $350.
It takes approximately 9h 54m to get from Santiago to Cuenca, including transfers.
Santiago to Cuenca bus services, operated by Lineas de Los Andes, depart from Terminal San Borja station.
The best way to get from Santiago to Cuenca is to fly which takes 9h 54m and costs $240 - $650. Alternatively, you can bus via Piura, which costs $280 - $350 and takes 2 days 21h.
Santiago to Cuenca bus services, operated by Lineas de Los Andes, arrive at Gran Terminal Terrestre Plaza Norte station.
Cuenca is 2h behind Santiago. It is currently 10:59 PM in Santiago and 8:59 PM in Cuenca.
What companies run services between Santiago, Chile and Cuenca, Ecuador?
LATAM Chile and Avianca - Aerovías del Continente Americano S.A. fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Cuenca (CUE) 3 times a day. Alternatively, you can take a bus from Terminal San Borja to Terminal de Cuenca via Gran Terminal Terrestre Plaza Norte, Piura, and Terminal de Piura in around 2d 21h.
- Website
- latam.com
Flights from Comodoro Arturo Merino Benítez International Airport to Cuenca via José Joaquín De Olmedo International Airport
- Ave. Duration
- 7h 29m
- When
- Saturday
- Estimated price
- $160–550
Flights from Comodoro Arturo Merino Benítez International Airport to Cuenca via Lima, Quito
- Ave. Duration
- 12h 59m
- When
- Monday, Tuesday, Wednesday, Thursday, and Saturday
- Estimated price
- $170–600
Flights from Comodoro Arturo Merino Benítez International Airport to Cuenca via José Joaquín De Olmedo International Airport, Quito
- Ave. Duration
- 13h 20m
- When
- Thursday
- Estimated price
- $170–600
Flights from Comodoro Arturo Merino Benítez International Airport to Cuenca via Lima, José Joaquín De Olmedo International Airport
- Ave. Duration
- 13h 29m
- When
- Friday
- Estimated price
- $160–550
Flights from Comodoro Arturo Merino Benítez International Airport to Tumbes via Lima
- Ave. Duration
- 8h 20m
- When
- Every day
- Estimated price
- $170–750
Flights from Comodoro Arturo Merino Benítez International Airport to Tumbes via Cuzco, Lima
- Ave. Duration
- 12h 50m
- When
- Every day
- Estimated price
- $230–800
Flights from Comodoro Arturo Merino Benítez International Airport to José Joaquín De Olmedo International Airport
- Ave. Duration
- 5h 18m
- When
- Every day
- Estimated price
- $220–550
Flights from Comodoro Arturo Merino Benítez International Airport to José Joaquín De Olmedo International Airport via Lima
- Ave. Duration
- 7h 55m
- When
- Every day
- Estimated price
- $220–550
- Phone
- +51 9 6788 4526
- [email protected]
- Website
- Lineas De Los Andes
Bus from Terminal San Borja to Gran Terminal Terrestre Plaza Norte
- Ave. Duration
- 45h 7m
- Frequency
- Once daily
- Estimated price
- $210–260
- Website
- Lineas De Los Andes
- Ave. Duration
- 3h 4m
- Estimated price
- $110–140
Aeropuerto g y e taxis
- Phone
- +593 96 015 5142
- Website
- facebook.com
Auto Amigo
- Phone
- +593 99 317 1528
- Website
- facebook.com
Ivan Car
- Phone
- +593 0 4371 1800
- Website
- ivancar-ec.com
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More Questions & Answers
Yes, the driving distance between Santiago to Cuenca is 4692 km. It takes approximately 2 days 14h to drive from Santiago to Cuenca.
There are 466+ hotels available in Cuenca.


