There are 8 ways to get from Santiago to Cuenca by plane, bus, car, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Cuenca
best- Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Cuenca (CUE)plane SCL - CUE
12h 29m$242–602Bus
cheapest- Take the bus from Terminal Sur de Santiago to Lima Javier Pradobus
- Take the bus from Lima Terminal Excluciva to Tumbesbus
- Take the bus from Huaquillas to Cuencabus
3d 6h$145–244Drive 4,690.2 km
- Drive from Santiago to Cuencacar 4,690.2 km
2d 14h$579–836Fly to José Joaquín De Olmedo International Airport, taxi
- Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to José Joaquín De Olmedo International Airport (GYE)plane SCL - GYE
- Take the taxi from Guayaquil-Airport-GYE to Cuencataxi
10h 47m$332–742Fly to Tumbes, bus
- Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Tumbes (TBP)plane SCL - TBP
- Take the bus from Huaquillas to Cuencabus
14h 5m$223–346Bus via Chiclayo
- Take the bus from Terminal Sur de Santiago to Gran Terminal Terrestre Plaza Nortebus
- Take the bus from Lima to Chiclayobus
- Take the bus from Chiclayo to Cuencabus
3d 6h$166–270Bus via Piura
- Take the bus from Terminal Sur de Santiago to Lima Javier Pradobus
- Take the bus from Lima Javier Prado to Piurabus
- Take the bus from Terminal de Piura to Terminal de Cuencabus
3d 11h$155–246Bus #2
- Take the bus from Terminal Sur de Santiago to Lima Javier Pradobus
- Take the bus from Lima Javier Prado to Terminal Terrestre de Guayaquilbus
- Take the bus from Terminal Terrestre de Guayaquil to Cuencabus
3d 16h$150–299
Comodoro Arturo Merino Benítez International Airport (SCL) to Cuenca (CUE) flights
Comparing Your Travel Options
The cheapest way to get from Santiago to Cuenca is to bus which costs $140 - $250 and takes 3 days 6h.
The fastest way to get from Santiago to Cuenca is to fly and taxi which takes 10h 47m and costs $330 - $750.
No, there is no direct bus from Santiago to Cuenca. However, there are services departing from Terminal Sur de Santiago and arriving at Cuenca via Lima Terminal Excluciva and Huaquillas. The journey, including transfers, takes approximately 3 days 6h.
The distance between Santiago and Cuenca is 3511 km. The road distance is 4690.2 km.
The best way to get from Santiago to Cuenca without a car is to bus via Chiclayo which takes 3 days 6h and costs $160 - $270.
It takes approximately 12h 29m to get from Santiago to Cuenca, including transfers.
Santiago to Cuenca bus services, operated by Cruz Del Sur International, depart from Terminal Sur de Santiago station.
The best way to get from Santiago to Cuenca is to fly which takes 12h 29m and costs $240 - $600. Alternatively, you can bus, which costs $140 - $250 and takes 3 days 6h.
Santiago to Cuenca bus services, operated by Cruz Del Sur International, arrive at Lima Javier Prado station.
Cuenca is 2h behind Santiago. It is currently 11:14 AM in Santiago and 9:14 AM in Cuenca.
What companies run services between Santiago, Chile and Cuenca, Ecuador?
LATAM Chile flies from Comodoro Arturo Merino Benítez International Airport (SCL) to Cuenca (CUE) twice daily. Alternatively, you can take a bus from Terminal Sur de Santiago to Cuenca via Lima Javier Prado, Lima Terminal Excluciva, Tumbes, and Huaquillas in around 3d 6h.
- Website
- latam.com
Flights from Comodoro Arturo Merino Benítez International Airport to Cuenca via José Joaquín De Olmedo International Airport
- Ave. Duration
- 10h 4m
- When
- Monday, Tuesday, Wednesday, Thursday, and Sunday
- Estimated price
- $240–600
Flights from Comodoro Arturo Merino Benítez International Airport to Cuenca via Quito
- Ave. Duration
- 13h 15m
- When
- Tuesday
- Estimated price
- $240–600
Flights from Comodoro Arturo Merino Benítez International Airport to Cuenca via Lima, José Joaquín De Olmedo International Airport
- Ave. Duration
- 15h 24m
- When
- Monday, Tuesday, Wednesday, Saturday, and Sunday
- Estimated price
- $240–600
Flights from Comodoro Arturo Merino Benítez International Airport to Cuenca via Quito, José Joaquín De Olmedo International Airport
- Ave. Duration
- 16h 49m
- When
- Tuesday
- Estimated price
- $240–600
Flights from Comodoro Arturo Merino Benítez International Airport to José Joaquín De Olmedo International Airport
- Ave. Duration
- 5h 18m
- When
- Every day
- Estimated price
- $220–600
Flights from Comodoro Arturo Merino Benítez International Airport to José Joaquín De Olmedo International Airport via Lima
- Ave. Duration
- 7h 42m
- When
- Every day
- Estimated price
- $220–600
Flights from Comodoro Arturo Merino Benítez International Airport to Tumbes via Lima
- Ave. Duration
- 9h 20m
- When
- Every day
- Estimated price
- $200–650
Flights from Comodoro Arturo Merino Benítez International Airport to Tumbes via Cuzco, Lima
- Ave. Duration
- 8h 50m
- When
- Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $210–700
- Website
- avianca.com
Flights from Comodoro Arturo Merino Benítez International Airport to José Joaquín De Olmedo International Airport via Bogota
- Ave. Duration
- 9h 30m
- When
- Every day
- Estimated price
- $240–490
- Website
- skyairline.com
Flights from Comodoro Arturo Merino Benítez International Airport to Tumbes via Lima
- Ave. Duration
- 7h 2m
- When
- Thursday to Sunday
- Estimated price
- $160–650
- Phone
- +51 1 311-5050
- Website
- Cruz Del Sur International
Bus from Terminal Sur de Santiago to Lima Javier Prado
- Ave. Duration
- 2d 6h
- Frequency
- Once daily
- Estimated price
- $95–170
- Website
- Cruz Del Sur International
Bus from Terminal Sur de Santiago to Gran Terminal Terrestre Plaza Norte
- Ave. Duration
- 2d 7h
- Frequency
- Once daily
- Estimated price
- $95–170
- Website
- Cruz Del Sur International
Bus from Terminal Sur de Santiago to Lima Javier Prado
- Ave. Duration
- 2d 6h
- Frequency
- Once daily
- Estimated price
- $95–170
- Website
- Cruz Del Sur International
Bus from Terminal Sur de Santiago to Lima Javier Prado
- Ave. Duration
- 2d 6h
- Frequency
- Once daily
- Estimated price
- $95–170
- Website
- Cruz Del Sur International
Bus from Lima Javier Prado to Terminal Terrestre de Guayaquil
- Ave. Duration
- 29h 19m
- Frequency
- Once a week
- Estimated price
- $45–100
- Website
- Cruz Del Sur International
- Phone
- +51 511 418 1111
- [email protected]
- Website
- CIVA
Bus from Lima Terminal Excluciva to Tumbes
- Ave. Duration
- 17h 55m
- Frequency
- Every 4 hours
- Estimated price
- $35–55
- Schedules at
- CIVA
- Phone
- +593-07 2823163
- [email protected]
- Website
- transportesazuay.com
Bus from Huaquillas to Cuenca
- Ave. Duration
- 4h
- Frequency
- Hourly
- Estimated price
- $8–19
- Schedules at
- transportesazuay.com
Bus from Huaquillas to Cuenca
- Ave. Duration
- 4h
- Frequency
- Hourly
- Estimated price
- $8–19
- Schedules at
- transportesazuay.com
Bus from Chiclayo to Cuenca
- Ave. Duration
- 10h
- Frequency
- Once daily
- Estimated price
- $27–60
- Schedules at
- transportesazuay.com
- Phone
- +51 979 707 957
- [email protected]
- Website
- terramovilperu.com.pe
Bus from Lima to Chiclayo
- Ave. Duration
- 10h 30m
- Frequency
- Hourly
- Estimated price
- $35
- Schedules at
- terramovilperu.com.pe
- Book at
- redbus.pe
- Phone
- +51 1 311 5050
- Website
- Cruz del Sur
Bus from Lima Javier Prado to Piura
- Ave. Duration
- 18h 55m
- Frequency
- Every 30 minutes
- Estimated price
- $23–45
- Website
- Cruz del Sur
- Phone
- +593 98 453 6454
- [email protected]
- Website
- facebook.com
Bus from Terminal de Piura to Terminal de Cuenca
- Ave. Duration
- 9h
- Frequency
- Once daily
- Estimated price
- $34–37
- Book at
- redbus.pe
Bus from Terminal Terrestre de Guayaquil to Cuenca
- Ave. Duration
- 4h 15m
- Frequency
- Every 4 hours
- Estimated price
- $11–35
- Book at
- redbus.pe
- Phone
- +593 99 144 1474
- [email protected]
- Website
- facebook.com
Bus from Terminal Terrestre de Guayaquil to Cuenca
- Ave. Duration
- 3h 30m
- Frequency
- Hourly
- Estimated price
- $8–11
- Schedules at
- facebook.com
- Book at
- ecuabuses.com
- Phone
- +593 09 9900 8843
- [email protected]
Bus from Terminal Terrestre de Guayaquil to Cuenca
- Ave. Duration
- 3h 35m
- Frequency
- 5 times a day
- Estimated price
- $7–10
- Schedules at
- facebook.com
- Ave. Duration
- 3h 4m
- Estimated price
- $110–140
Aeropuerto g y e taxis
- Phone
- +593 96 015 5142
- Website
- facebook.com
Auto Amigo
- Phone
- +593 99 317 1528
- Website
- facebook.com
Ivan Car
- Phone
- +593 0 4371 1800
- Website
- ivancar-ec.com
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Booking & Getting There
Yes, the driving distance between Santiago to Cuenca is 4690 km. It takes approximately 2 days 14h to drive from Santiago to Cuenca.
There are 422+ hotels available in Cuenca.

















