There are 4 ways to get from Santiago to Cusco by plane, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Alejandro Velasco Astete International Airport (CUZ)plane SCL - CUZ
5h 55m$132–322Bus
cheapest- Take the bus from Terminal San Borja to Terminal Rodoviario de Aricabus
- Take the bus from Terminal Internacional to Tacnabus
- Take the bus from Tacna Bus Station to Cusco Bus Stationbus
47h 1m$91–174Drive 2,878.1 km
- Drive from Santiago to Cuscocar 2,878.1 km
38h 46m$433–625Bus via Oruro Airport (ORU)
- Take the bus from Terminal Alameda - Turbus to Orurobus
- Take the bus from Oruro to La Pazbus
- Take the bus from La Paz to Cuscobus
2d 6h$106–116
Comodoro Arturo Merino Benítez International Airport (SCL) to Alejandro Velasco Astete International Airport (CUZ) flights
Questions & Answers
The cheapest way to get from Santiago to Cusco is to bus which costs $90 - $180 and takes 47h 1m.
The fastest way to get from Santiago to Cusco is to fly which takes 5h 55m and costs $130 - $330.
No, there is no direct bus from Santiago to Cusco station. However, there are services departing from Terminal San Borja and arriving at Cusco Bus Station via Terminal Internacional and Tacna Bus Station. The journey, including transfers, takes approximately 47h 1m.
The distance between Santiago and Cusco is 2225 km. The road distance is 2878.1 km.
The best way to get from Santiago to Cusco without a car is to bus which takes 47h 1m and costs $90 - $180.
It takes approximately 5h 55m to get from Santiago to Cusco, including transfers.
Santiago to Cusco bus services, operated by Pullman Bus, depart from Terminal San Borja station.
The best way to get from Santiago to Cusco is to fly which takes 5h 55m and costs $130 - $330. Alternatively, you can bus, which costs $90 - $180 and takes 47h 1m.
Santiago to Cusco bus services, operated by Pullman Bus, arrive at Terminal Rodoviario de Arica station.
Cusco is 2h behind Santiago. It is currently 7:56 AM in Santiago and 5:56 AM in Cusco.
What companies run services between Santiago, Chile and Cusco, Peru?
LATAM Chile, Sky Airline, and JetSMART fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Alejandro Velasco Astete International Airport (CUZ) every 3 hours. Alternatively, you can take a bus from Terminal San Borja to Cusco Bus Station via Terminal Rodoviario de Arica, Terminal Internacional, and Tacna Bus Station in around 47h 1m.
- Website
- latam.com
Flights from Comodoro Arturo Merino Benítez International Airport to Alejandro Velasco Astete International Airport
- Ave. Duration
- 3h 30m
- When
- Every day
- Estimated price
- $150–330
Flights from Comodoro Arturo Merino Benítez International Airport to Alejandro Velasco Astete International Airport via Lima
- Ave. Duration
- 6h 24m
- When
- Every day
- Estimated price
- $150–330
- Phone
- +56 600 600 0018
- [email protected]
- Website
- pullmanbus.cl
Bus from Terminal San Borja to Terminal Rodoviario de Arica
- Ave. Duration
- 29h 5m
- Frequency
- 5 times a day
- Estimated price
- $60–80
- Schedules at
- pullmanbus.cl
- Book at
- pullmanbus.cl
- Salón Cama
- $60–80
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More Questions & Answers
Yes, the driving distance between Santiago to Cusco is 2878 km. It takes approximately 38h 46m to drive from Santiago to Cusco.
There are 1478+ hotels available in Cusco.



