There are 4 ways to get from Santiago to Cusco by plane, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Alejandro Velasco Astete International Airport (CUZ)plane SCL - CUZ
5h 55m$142–322Bus
cheapest- Take the bus from Terminal San Borja to Terminal Rodoviario de Aricabus
- Take the bus from Terminal Internacional to Tacnabus
- Take the bus from Tacna Bus Station to Cusco Bus Stationbus
47h 51m$94–179Drive 2,855.7 km
- Drive from Santiago to Cuscocar 2,855.7 km
37h 35m$430–620Bus via Oruro Airport (ORU)
- Take the bus from Terminal Alameda - Turbus to Orurobus
- Take the bus from Oruro to La Pazbus
- Take the bus from La Paz to Cuscobus
2d 6h$103–113
Comodoro Arturo Merino Benítez International Airport (SCL) to Alejandro Velasco Astete International Airport (CUZ) flights
Questions & Answers
The cheapest way to get from Santiago to Cusco is to bus via Oruro Airport (ORU) which costs $100 - $120 and takes 2 days 6h.
The fastest way to get from Santiago to Cusco is to fly which takes 5h 55m and costs $140 - $330.
No, there is no direct bus from Santiago to Cusco station. However, there are services departing from Terminal San Borja and arriving at Cusco Bus Station via Terminal Internacional and Tacna Bus Station. The journey, including transfers, takes approximately 47h 51m.
The distance between Santiago and Cusco is 2225 km. The road distance is 2855.7 km.
The best way to get from Santiago to Cusco without a car is to bus which takes 47h 51m and costs $90 - $180.
It takes approximately 5h 55m to get from Santiago to Cusco, including transfers.
Santiago to Cusco bus services, operated by Pullman San Andres, depart from Terminal San Borja station.
The best way to get from Santiago to Cusco is to fly which takes 5h 55m and costs $140 - $330. Alternatively, you can bus, which costs $90 - $180 and takes 47h 51m.
Santiago to Cusco bus services, operated by Pullman San Andres, arrive at Terminal Rodoviario de Arica station.
Cusco is 1h behind Santiago. It is currently 3:00 PM in Santiago and 2:00 PM in Cusco.
What companies run services between Santiago, Chile and Cusco, Peru?
LATAM Chile, Sky Airline, and JetSMART fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Alejandro Velasco Astete International Airport (CUZ) every 3 hours. Alternatively, you can take a bus from Terminal San Borja to Cusco Bus Station via Terminal Rodoviario de Arica, Terminal Internacional, and Tacna Bus Station in around 47h 51m.
- Website
- latam.com
Flights from Comodoro Arturo Merino Benítez International Airport to Alejandro Velasco Astete International Airport
- Ave. Duration
- 3h 30m
- When
- Every day
- Estimated price
- $160–380
Flights from Comodoro Arturo Merino Benítez International Airport to Alejandro Velasco Astete International Airport via Lima
- Ave. Duration
- 6h 33m
- When
- Every day
- Estimated price
- $160–380
- Website
- skyairline.com
Flights from Comodoro Arturo Merino Benítez International Airport to Alejandro Velasco Astete International Airport via Lima
- Ave. Duration
- 6h 57m
- When
- Every day
- Estimated price
- $150–310
- Website
- jetsmart.com
Flights from Comodoro Arturo Merino Benítez International Airport to Alejandro Velasco Astete International Airport via Lima
- Ave. Duration
- 6h 24m
- When
- Tuesday and Wednesday
- Estimated price
- $130–330
- [email protected]
- Website
- pullmansanandres.cl
Bus from Terminal San Borja to Terminal Rodoviario de Arica
- Ave. Duration
- 29h 55m
- Frequency
- Hourly
- Estimated price
- $90–140
- Schedules at
- pullmansanandres.cl
- Semi Cama
- $90–130
- Cama
- $100–140
- Phone
- +56 600 600 0018
- [email protected]
- Website
- pullmanbus.cl
Bus from Terminal San Borja to Terminal Rodoviario de Arica
- Ave. Duration
- 29h 5m
- Frequency
- 5 times a day
- Estimated price
- $60–85
- Schedules at
- pullmanbus.cl
- Book at
- pullmanbus.cl
- Salón Cama
- $60–85
- Phone
- +56 58 222 8603
- [email protected]
- Website
- recorrido.cl
Bus from Terminal Internacional to Tacna
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- $5
- Website
- https://www.recorrido.cl/en/bus/buses-norte-grande-tickets
- Phone
- +51 051 602 943
- Website
- facebook.com
Bus from Tacna Bus Station to Cusco Bus Station
- Ave. Duration
- 15h 30m
- Frequency
- Twice daily
- Estimated price
- $24–35
- Schedules at
- facebook.com
- Phone
- +591 2527 7355
- [email protected]
- Website
- facebook.com
Bus from Terminal Alameda - Turbus to Oruro
- Ave. Duration
- 33h 2m
- Frequency
- 4 times a week
- Estimated price
- $43
- Schedules at
- facebook.com
- Phone
- +59 128 1779
- [email protected]
- Website
- facebook.com
Bus from Oruro to La Paz
- Ave. Duration
- 4h 30m
- Frequency
- Once daily
- Website
- https://boliviatravelsite.com/predilecto-bus
- Phone
- +591 466-60443
- [email protected]
- Website
- facebook.com
Bus from Oruro to La Paz
- Ave. Duration
- 5h 6m
- Frequency
- Once daily
- Estimated price
- $13–23
- Schedules at
- facebook.com
- Phone
- +591 22283843
- [email protected]
- Website
- facebook.com
Bus from La Paz to Cusco
- Ave. Duration
- 14h
- Frequency
- Twice daily
- Estimated price
- $40–340
- Book at
- https://www.ticketsbolivia.com/company/nc_internacional.php
- Phone
- +591 2 228 1920
- [email protected]
- Website
- facebook.com
Bus from La Paz to Cusco
- Ave. Duration
- 15h
- Frequency
- Once daily
- Estimated price
- $45
- Schedules at
- redbus.pe
Want to know more about travelling around the world?
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More Questions & Answers
Yes, the driving distance between Santiago to Cusco is 2856 km. It takes approximately 37h 35m to drive from Santiago to Cusco.
There are 1388+ hotels available in Cusco.
























