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How to get fromSantiago to Esquipulasby plane or bus

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There are 4 ways to get from Santiago to Esquipulas by plane or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Cuscatlán International Airport, bus

    best
    1. Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Cuscatlán International Airport (SAL)plane plane SCL - SAL
    2. Take the bus from San Salvador Airport to San Salvadorbus bus
    3. Take the bus from San Salvador to San Ignaciobus bus
    15h 26m
    $368–711

  2. Fly to Ramón Villeda Morales International Airport, bus

    cheapest
    1. Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Ramón Villeda Morales International Airport (SAP)plane plane SCL - SAP
    2. Take the bus from Terminal Metropolitana de Buses to Esquipulasbus bus
    16h 24m
    $242–897

  3. Fly to La Aurora International Airport, bus

    1. Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to La Aurora International Airport (GUA)plane plane SCL - GUA
    2. Take the bus from Guatemala to Esquipulasbus bus
    15h 59m
    $335–884

  4. Fly to Palmerola Airport, bus

    1. Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Palmerola Airport (XPL)plane plane SCL - XPL
    2. Take the bus from Siguatepeque to La Esperanzabus bus
    3. Take the bus from La Esperanza to Santa Rosa de Copánbus bus
    4. Take the bus from Santa Rosa de Copán to Esquipulasbus bus
    19h 32m

Comodoro Arturo Merino Benítez International Airport (SCL) to Cuscatlán International Airport (SAL) flights

Calendar43Weekly Planes
Duration12h 9mAverage Duration
Ticket$191Cheapest Price
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Comparing Your Travel Options

Map of how to get from Santiago to Esquipulas.ExpandLaunch map view
  • Distance: 5,750.7 km
  • Duration: 15h 26m

What companies run services between Santiago, Chile and Esquipulas, Chiquimula, Guatemala?

There is no direct connection from Santiago to Esquipulas. However, you can take the bus to Estación de Buses Aeropuerto Internacional Arturo Merino Benítez, walk to Comodoro Arturo Merino Benítez International Airport (SCL) airport, fly to Cuscatlán International Airport (SAL), walk to San Salvador Airport, take the bus to San Salvador, take the bus to San Ignacio, drive to Nueva Ocotepeque, then take the bus to Esquipulas. Alternatively, you can take the bus to Estación de Buses Aeropuerto Internacional Arturo Merino Benítez, walk to Comodoro Arturo Merino Benítez International Airport (SCL) airport, fly to Ramón Villeda Morales International Airport (SAP), take the taxi to Terminal Metropolitana de Buses, then take the bus to Esquipulas.

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