There are 5 ways to get from Santiago to Esquipulas by plane or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Comodoro Arturo Merino Benítez International Airport to Cuscatlán International Airport, bus
best- Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Cuscatlán International Airport (SAL)plane SCL - SAL
- Take the bus from San Salvador Airport to San Salvadorbus
- Take the bus from San Salvador to San Ignaciobus
16h 28m$368–761Fly Comodoro Arturo Merino Benítez International Airport to Ramón Villeda Morales International Airport, bus
cheapest- Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Ramón Villeda Morales International Airport (SAP)plane SCL - SAP
- Take the bus from Terminal Metropolitana de Buses to Esquipulasbus
17h 29m$252–897Fly Comodoro Arturo Merino Benítez International Airport to La Aurora International Airport, bus
- Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to La Aurora International Airport (GUA)plane SCL - GUA
- Take the bus from Guatemala to Esquipulasbus
17h 21m$335–934Fly Comodoro Arturo Merino Benítez International Airport to Palmerola Airport, bus
- Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Palmerola Airport (XPL)plane SCL - XPL
- Take the bus from Siguatepeque to La Esperanzabus
- Take the bus from La Esperanza to Santa Rosa de Copánbus
- Take the bus from Santa Rosa de Copán to Esquipulasbus
20h 36mBus to Governor Francisco Gabrielli International Airport, fly to Cuscatlán International Airport, bus
- Take the bus from Terminal Alameda - Turbus to Terminal Mendozabus
- Fly from Governor Francisco Gabrielli International Airport (MDZ) to Cuscatlán International Airport (SAL)plane MDZ - SAL
- Take the bus from San Salvador Airport to San Salvadorbus
- Take the bus from San Salvador to San Ignaciobus
27h 23m$620–930
Comodoro Arturo Merino Benítez International Airport (SCL) to Cuscatlán International Airport (SAL) flights
Comparing Your Travel Options
The cheapest way to get from Santiago to Esquipulas is to fly and bus which costs $330 - $950 and takes 17h 21m.
The fastest way to get from Santiago to Esquipulas is to fly and bus which takes 16h 28m and costs $360 - $800.
The distance between Santiago and Esquipulas is 5751 km.
It takes approximately 16h 28m to get from Santiago to Esquipulas, including transfers.
Esquipulas is 3h behind Santiago. It is currently 7:41 PM in Santiago and 4:41 PM in Esquipulas.
There are 16+ hotels available in Esquipulas.
What companies run services between Santiago, Chile and Esquipulas, Chiquimula, Guatemala?
There is no direct connection from Santiago to Esquipulas. However, you can take the bus to Estación de Buses Aeropuerto Internacional Arturo Merino Benítez, walk to Comodoro Arturo Merino Benítez International Airport (SCL) airport, fly to Cuscatlán International Airport (SAL), walk to San Salvador Airport, take the bus to San Salvador, take the bus to San Ignacio, drive to Nueva Ocotepeque, then take the bus to Esquipulas. Alternatively, you can take the bus to Estación de Buses Aeropuerto Internacional Arturo Merino Benítez, walk to Comodoro Arturo Merino Benítez International Airport (SCL) airport, fly to Ramón Villeda Morales International Airport (SAP), take the taxi to Terminal Metropolitana de Buses, then take the bus to Esquipulas.
- Website
- copaair.com
Flights from Comodoro Arturo Merino Benítez International Airport to Cuscatlán International Airport via Panama City
- Ave. Duration
- 10h 53m
- When
- Every day
- Estimated price
- $190–750
Flights from Comodoro Arturo Merino Benítez International Airport to Ramón Villeda Morales International Airport via Panama City
- Ave. Duration
- 12h 24m
- When
- Every day
- Estimated price
- $210–800
Flights from Comodoro Arturo Merino Benítez International Airport to La Aurora International Airport via Panama City
- Ave. Duration
- 10h 41m
- When
- Every day
- Estimated price
- $170–700
Flights from Comodoro Arturo Merino Benítez International Airport to Palmerola Airport via Panama City
- Ave. Duration
- 11h 35m
- When
- Every day
- Estimated price
- $220–850
Flights from Governor Francisco Gabrielli International Airport to Cuscatlán International Airport via Panama City
- Ave. Duration
- 18h 21m
- When
- Every day
- Estimated price
- $250–1,000
- Website
- avianca.com
Flights from Comodoro Arturo Merino Benítez International Airport to Cuscatlán International Airport via Bogota
- Ave. Duration
- 12h 59m
- When
- Every day
- Estimated price
- $290–900
Flights from Comodoro Arturo Merino Benítez International Airport to La Aurora International Airport via Bogota
- Ave. Duration
- 12h 50m
- When
- Every day
- Estimated price
- $320–900
- Website
- aeromexico.com
Flights from Comodoro Arturo Merino Benítez International Airport to Cuscatlán International Airport via Mexico City
- Ave. Duration
- 17h 37m
- When
- Every day
- Estimated price
- $240–900
Flights from Comodoro Arturo Merino Benítez International Airport to Ramón Villeda Morales International Airport via Mexico City
- Ave. Duration
- 15h
- When
- Monday, Wednesday, Friday, and Saturday
- Estimated price
- $270–1,000
Flights from Comodoro Arturo Merino Benítez International Airport to La Aurora International Airport via Mexico City
- Ave. Duration
- 14h 44m
- When
- Every day
- Estimated price
- $210–800
Flights from Comodoro Arturo Merino Benítez International Airport to Palmerola Airport via Mexico City
- Ave. Duration
- 17h 41m
- When
- Wednesday, Thursday, Saturday, and Sunday
- Estimated price
- $290–1,100
- Website
- aa.com
Flights from Comodoro Arturo Merino Benítez International Airport to Cuscatlán International Airport via Miami
- Ave. Duration
- 15h 53m
- When
- Every day
- Estimated price
- $260–950
Flights from Comodoro Arturo Merino Benítez International Airport to Ramón Villeda Morales International Airport via Miami
- Ave. Duration
- 15h 59m
- When
- Every day
- Estimated price
- $280–1,000
Flights from Comodoro Arturo Merino Benítez International Airport to Palmerola Airport via Miami
- Ave. Duration
- 15h 37m
- When
- Every day
- Estimated price
- $290–1,100
- [email protected]
Bus from San Salvador Airport to San Salvador
- Ave. Duration
- 30 min
- Frequency
- Every 20 minutes
- Estimated price
- $1
- Schedules at
- centrocoasting.com
Bus from San Salvador to San Ignacio
- Ave. Duration
- 1h 20m
- Frequency
- Hourly
- Estimated price
- $2
- Schedules at
- centrocoasting.com
Bus from San Salvador Airport to San Salvador
- Ave. Duration
- 30 min
- Frequency
- Every 20 minutes
- Estimated price
- $1
- Schedules at
- centrocoasting.com
Bus from San Salvador to San Ignacio
- Ave. Duration
- 1h 20m
- Frequency
- Hourly
- Estimated price
- $2
- Schedules at
- centrocoasting.com
- Phone
- +504 3247 0793
- Website
- Transportes Congolón
Bus from Terminal Metropolitana de Buses to Esquipulas
- Ave. Duration
- 3h 43m
- Frequency
- On demand
- Estimated price
- $10–55
- Schedules at
- Transportes Congolón
Bus from Guatemala to Esquipulas
- Ave. Duration
- 2h 16m
- Frequency
- On demand
- Estimated price
- $6–11
- Schedules at
- Transportes Congolón
Bus from Santa Rosa de Copán to Esquipulas
- Ave. Duration
- 1h 33m
- Frequency
- On demand
- Estimated price
- $4–8
- Schedules at
- Transportes Congolón
- Phone
- +504 3256-9996
- Website
- Carolina'Tours
Bus from Siguatepeque to La Esperanza
- Ave. Duration
- 1h 4m
- Frequency
- Hourly
- Website
- Carolina'Tours
Bus from Siguatepeque to La Esperanza
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $3
- Schedules at
- Travel with Hello - Honduras public transport
- Phone
- +504 9475-9218
- [email protected]
- Website
- Transportes Gracianos
Bus from La Esperanza to Santa Rosa de Copán
- Ave. Duration
- 2h
- Frequency
- Once daily
- Website
- Transportes Gracianos
- Phone
- +56 22 822 7500
- [email protected]
- Website
- turbus.cl
Bus from Terminal Alameda - Turbus to Terminal Mendoza
- Semi Cama
- $13–18
- Cama
- $16–23
- Premium
- $55–70
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