What is the cheapest way to get from Santiago to La Serena?

The cheapest way to get from Santiago to La Serena is to bus via Quilimarí which costs $12 - $35 and takes 6h 37m.

What is the fastest way to get from Santiago to La Serena?

The fastest way to get from Santiago to La Serena is to fly which takes 2h 31m and costs $23 - $85.

Is there a direct bus between Santiago and La Serena?

Yes, there is a direct bus departing from Terminal San Borja and arriving at Terminal de buses La Serena. Services depart every 30 minutes, and operate every day. The journey takes approximately 6h 20m.

How far is it from Santiago to La Serena?

The distance between Santiago and La Serena is 403 km. The road distance is 473.3 km.

How do I travel from Santiago to La Serena without a car?

The best way to get from Santiago to La Serena without a car is to bus which takes 6h 20m and costs $8 - $75.

How long does it take to get from Santiago to La Serena?

It takes approximately 2h 31m to get from Santiago to La Serena, including transfers.

Where do I catch the Santiago to La Serena bus from?

Santiago to La Serena bus services, operated by Pluss Chile, depart from Terminal San Borja station.

Bus or fly from Santiago to La Serena?

The best way to get from Santiago to La Serena is to fly which takes 2h 31m and costs $23 - $85. Alternatively, you can bus, which costs $8 - $75 and takes 6h 20m.

Where does the Santiago to La Serena bus arrive?

Santiago to La Serena bus services, operated by Pluss Chile, arrive at Terminal de buses La Serena station.

Can I drive from Santiago to La Serena?

Yes, the driving distance between Santiago to La Serena is 473 km. It takes approximately 4h 52m to drive from Santiago to La Serena.

How do I get a bus ticket from Santiago to La Serena?

Book your Santiago to La Serena bus tickets online with Omio, 12go.asia and FlixBus.

Where can I stay near La Serena?

There are 961+ hotels available in La Serena.

Santiago to La Serena - 5 ways to travel via plane, bus, and car

How to get fromSantiago to La Serena

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There are 5 ways to get from Santiago to La Serena by plane, bus (Flixbus), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly
best
1. Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to La Florida Airport (LSC)plane SCL - LSC
2h 31m
$23–82
Bus
cheapest
1. Take the bus from Terminal San Borja to Terminal de buses La Serenabus Santiago / ...
6h 20m
$8–75
Drive 473.3 km
1. Drive from Santiago to La Serenacar 473.3 km
4h 52m
$59–85
Bus via Quilimarí
1. Take the bus from Terminal San Borja to Pichidangui - Crucebus Santiago
2. Take the bus from Pichidangui - Cruce to Terminal de buses La Serenabus Santiago
6h 37m
$12–31
Bus via Santiago (Flixbus)
1. Take the bus from Santiago to Terminal de buses La Serenabus FlixBus CL040
6h 55m
$51–86

Santiago to La Serena by bus

902Weekly Buses

6h 20mAverage Duration

$8Cheapest Price

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Questions & Answers

Map of how to get from Santiago to La Serena.

Launch map view

Distance: 402.7 km
Duration: 2h 31m

What companies run services between Santiago, Chile and La Serena, Chile?

Sky Airline, JetSMART, and LATAM Chile fly from Comodoro Arturo Merino Benítez International Airport (SCL) to La Florida Airport (LSC) every 4 hours. Alternatively, Pluss Chile operates a bus from Terminal San Borja to Terminal de buses La Serena twice daily. Tickets cost $14–27 and the journey takes 6h 20m. 12 other operators also service this route.

Airlines