There are 5 ways to get from Santiago to Medellín by plane, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Medellin Jose Marie Cordova
best- Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Medellin Jose Marie Cordova (MDE)plane SCL - MDE
9h 30m$227–502Bus via Tumbes
cheapest- Take the bus from Terminal Sur de Santiago to Gran Terminal Terrestre Plaza Nortebus
- Take the bus from Gran Terminal Terrestre Plaza Norte to Tumbesbus
- Take the bus from Huaquillas to Tulcánbus
- Take the bus from Terminal de Transporte Ipiales to Terminal del Surbus
4d 13h$182–333Drive 6,148 km
- Drive from Santiago to Medellíncar 6,148 km
3d 14h$858–1,239Fly to Enrique Olaya Herrera Airport
- Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Enrique Olaya Herrera Airport (EOH)plane SCL - EOH
10h 31m$602–2,102Bus
- Take the bus from Terminal Sur de Santiago to Lima Javier Pradobus
- Take the bus from Lima Javier Prado to Terminal Terrestre Quitumbebus
- Take the bus from Terminal Terrestre Quitumbe to Tulcánbus
- Take the bus from Terminal de Transporte Ipiales to Terminal del Surbus
4d 20h$200–357
Comodoro Arturo Merino Benítez International Airport (SCL) to Medellin Jose Marie Cordova (MDE) flights
Comparing Your Travel Options
The cheapest way to get from Santiago to Medellín is to bus via Tumbes which costs $180 - $340 and takes 4 days 13h.
The fastest way to get from Santiago to Medellín is to fly which takes 9h 30m and costs $220 - $500.
No, there is no direct bus from Santiago to Medellín. However, there are services departing from Terminal Sur de Santiago and arriving at Terminal del Sur via Gran Terminal Terrestre Plaza Norte, Huaquillas and Terminal de Transporte Ipiales. The journey, including transfers, takes approximately 4 days 13h.
The distance between Santiago and Medellín is 4464 km. The road distance is 6148 km.
It takes approximately 9h 30m to get from Santiago to Medellín, including transfers.
Santiago to Medellín bus services, operated by Cruz Del Sur International, depart from Terminal Sur de Santiago station.
The best way to get from Santiago to Medellín is to fly which takes 9h 30m and costs $220 - $500. Alternatively, you can bus via Tumbes, which costs $180 - $340 and takes 4 days 13h.
Santiago to Medellín bus services, operated by Cruz Del Sur International, arrive at Gran Terminal Terrestre Plaza Norte station.
Medellín is 2h behind Santiago. It is currently 10:39 AM in Santiago and 8:39 AM in Medellín.
Yes, the driving distance between Santiago to Medellín is 6148 km. It takes approximately 3 days 14h to drive from Santiago to Medellín.
What companies run services between Santiago, Chile and Medellín, Colombia?
JetSMART, LATAM Chile, and two other airlines fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Medellin Jose Marie Cordova (MDE) every 2 hours. Alternatively, you can take a bus from Terminal Sur de Santiago to Terminal del Sur via Gran Terminal Terrestre Plaza Norte, Tumbes, Huaquillas, Tulcán, and Terminal de Transporte Ipiales in around 4d 13h.
- Website
- avianca.com
Flights from Comodoro Arturo Merino Benítez International Airport to Medellin Jose Marie Cordova via Bogota
- Ave. Duration
- 8h 30m
- When
- Every day
- Estimated price
- $250–850
Flights from Comodoro Arturo Merino Benítez International Airport to Medellin Jose Marie Cordova via Cartagena
- Ave. Duration
- 9h 35m
- When
- Wednesday, Friday, and Sunday
- Estimated price
- $270–900
Flights from Comodoro Arturo Merino Benítez International Airport to Enrique Olaya Herrera Airport via Bogota
- Ave. Duration
- 9h 52m
- When
- Every day
- Estimated price
- $850–2,800
- Website
- latam.com
Flights from Comodoro Arturo Merino Benítez International Airport to Medellin Jose Marie Cordova via Bogota
- Ave. Duration
- 8h 33m
- When
- Every day
- Estimated price
- $190–600
Flights from Comodoro Arturo Merino Benítez International Airport to Medellin Jose Marie Cordova via Lima
- Ave. Duration
- 9h 45m
- When
- Every day
- Estimated price
- $190–600
- Website
- copaair.com
Flights from Comodoro Arturo Merino Benítez International Airport to Medellin Jose Marie Cordova via Panama City
- Ave. Duration
- 9h 43m
- When
- Every day
- Estimated price
- $140–600
- Website
- jetsmart.com
Flights from Comodoro Arturo Merino Benítez International Airport to Medellin Jose Marie Cordova
- Ave. Duration
- 6h 15m
- When
- Monday, Tuesday, Friday, Saturday, and Sunday
- Estimated price
- $200–350
Flights from Comodoro Arturo Merino Benítez International Airport to Medellin Jose Marie Cordova via Bogota
- Ave. Duration
- 8h 41m
- When
- Tuesday
- Estimated price
- $200–350
Flights from Comodoro Arturo Merino Benítez International Airport to Medellin Jose Marie Cordova via Cali
- Ave. Duration
- 8h 44m
- When
- Sunday
- Estimated price
- $200–350
- Website
- satena.com
Flights from Comodoro Arturo Merino Benítez International Airport to Enrique Olaya Herrera Airport via Bogota
- Ave. Duration
- 7h 48m
- When
- Thursday, Monday, Tuesday, Friday, and Saturday
- Estimated price
- $600–2,100
- Website
- easyfly.com.co
Flights from Comodoro Arturo Merino Benítez International Airport to Enrique Olaya Herrera Airport via Antofagasta, Cali
- Ave. Duration
- 10h
- When
- Saturday
- Estimated price
- $600–2,100
- Phone
- +51 1 311-5050
- Website
- Cruz Del Sur International
Bus from Terminal Sur de Santiago to Gran Terminal Terrestre Plaza Norte
- Ave. Duration
- 2d 7h
- Frequency
- Once daily
- Estimated price
- $95–170
- Website
- Cruz Del Sur International
Bus from Terminal Sur de Santiago to Lima Javier Prado
- Ave. Duration
- 2d 6h
- Frequency
- Once daily
- Estimated price
- $95–170
- Website
- Cruz Del Sur International
Bus from Lima Javier Prado to Terminal Terrestre Quitumbe
- Ave. Duration
- 35h 35m
- Frequency
- Once a week
- Estimated price
- $55–100
- Website
- Cruz Del Sur International
- Phone
- +51 511 418 1111
- [email protected]
- Website
- CIVA
Bus from Gran Terminal Terrestre Plaza Norte to Tumbes
- Ave. Duration
- 17h 10m
- Frequency
- Every 4 hours
- Estimated price
- $35–55
- Schedules at
- CIVA
- Phone
- +51 1 4800725
- [email protected]
- Website
- floreshnos.pe
Bus from Gran Terminal Terrestre Plaza Norte to Tumbes
- Ave. Duration
- 19h
- Frequency
- Every 4 hours
- Estimated price
- $29–45
- Schedules at
- floreshnos.pe
- Book at
- floreshnos.pe
- Phone
- +51 994 656 518
- [email protected]
- Website
- Oltursa
Bus from Gran Terminal Terrestre Plaza Norte to Tumbes
- Ave. Duration
- 22h
- Frequency
- Twice daily
- Estimated price
- $28–40
- Website
- Oltursa
- Phone
- +593 062980728
- [email protected]
- Website
- Cooperativa Tax Gacela
Bus from Huaquillas to Tulcán
- Ave. Duration
- 14h
- Frequency
- Every 4 hours
- Estimated price
- $11–24
- Schedules at
- Cooperativa Tax Gacela
Bus from Terminal Terrestre Quitumbe to Tulcán
- Ave. Duration
- 5h
- Frequency
- Hourly
- Estimated price
- $6–10
- Schedules at
- Cooperativa Tax Gacela
- Phone
- +57 601 4249090
- [email protected]
- Website
- bolivariano.com.co
Bus from Terminal de Transporte Ipiales to Terminal del Sur
- Ave. Duration
- 19h 39m
- Frequency
- Every 4 hours
- Estimated price
- $40–80
- Schedules at
- bolivariano.com.co
- Book at
- bolivariano.com.co
Bus from Terminal de Transporte Ipiales to Terminal del Sur
- Ave. Duration
- 19h 39m
- Frequency
- Every 4 hours
- Estimated price
- $40–80
- Schedules at
- bolivariano.com.co
- Book at
- bolivariano.com.co
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