How to get fromSantiago to Panamaby plane, bus, ferry, or car

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There are 4 ways to get from Santiago to Panama by plane, bus, ferry, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly to Tocumen International Airport
best
1. Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Tocumen International Airport (PTY)plane SCL - PTY
9h 59m
$352–592
Fly to David
cheapest
1. Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to David (DAV)plane SCL - DAV
11h 57m
$245–906
Bus, ferry, drive
1. Take the bus from Terminal San Borja to Cúcutabus
2. Take the bus from Terminal Cúcuta to Terminal de Transporte de Cartagenabus
3. Take the ferry from Cartagena to Portobeloferry
4. Drive from Portobelo to Panama Citycar
10d 14h
$1,191–1,304
Fly to Panama Pacific International Airport
1. Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Panama Pacific International Airport (BLB)plane SCL - BLB
12h 28m
$259–723

Comodoro Arturo Merino Benítez International Airport (SCL) to Tocumen International Airport (PTY) flights

68Weekly Planes

8h 4mAverage Duration

$158Cheapest Price

Questions & Answers

Map of how to get from Santiago to Panama.

Launch map view

Distance: 4,845 km
Duration: 9h 59m

What companies run services between Santiago, Chile and Panama?

Copa Airlines and Avianca - Aerovías del Continente Americano S.A. fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Tocumen International Airport (PTY) every 3 hours.

Airlines

Bus operators

Ferry operators

Want to know more about travelling around the world?

Rome2Rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including How to get from Luton Airport into central London, How to travel India's Golden Triangle, and Travelling around the UAE - to help you get the most out of your next trip.

Panama City, Panama(opens in a new window)

Panama City, also known as Panama (or Panamá in Spanish), is the capital and largest city of Panama. It has a total population of 1,938,000, with over 1,500,000 in its urban area. The city is located at the Pacific entrance of the Panama Canal, in the province of Panama. The city is the political and administrative center of the country, as well as a hub for banking and commerce.

Places to stay in Panama City

Plaza Paitilla Inn(Opens in a new window)

8.9Fabulous

Ramada Plaza by Wyndham Panama Punta Pacifica(Opens in a new window)

9.2Superb

Megapolis Hotel Panama(Opens in a new window)

8.5Very Good

Global Hotel Panama(Opens in a new window)

8.6Fabulous

Rome2Rio makes travelling from Santiago to Panama easy.

Rome2Rio is a door-to-door travel information and booking engine, helping you get to and from any location in the world. Find all the transport options for your trip from Santiago to Panama right here. Rome2Rio displays up to date schedules, route maps, journey times and estimated fares from relevant transport operators, ensuring you can make an informed decision about which option will suit you best. Rome2Rio also offers online bookings for selected operators, making reservations easy and straightforward.