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How to get fromSantiago to Santa Anaby plane, train, or bus

Find Transport to Santa Ana

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There are 7 ways to get from Santiago to Santa Ana by plane, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to John Wayne Airport Orange County

    best
    1. Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to John Wayne Airport Orange County (SNA)plane plane SCL - SNA
    16h 35m
    $381–1,337

  2. Fly to San Diego International Airport, train

    cheapest
    1. Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to San Diego International Airport (SAN)plane plane SCL - SAN
    2. Take the train from San Diego to Santa Anatrain train
    20h 1m
    $296–1,062

  3. Fly to Los Angeles International Airport, train

    1. Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Los Angeles International Airport (LAX)plane plane SCL - LAX
    2. Take the train from Los Angeles to Santa Anatrain train
    16h 28m
    $387–1,135

  4. Fly to Tijuana International Airport, bus

    1. Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Tijuana International Airport (TIJ)plane plane SCL - TIJ
    2. Take the bus from Tijuana Aeropuerto, B.C. to Santa Anabus bus
    18h 20m
    $492–2,747

  5. Fly to Palm Springs International Airport, bus

    1. Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Palm Springs International Airport (PSP)plane plane SCL - PSP
    2. Take the bus from Palm Springs Airport Amtrak Bus Stop to Fullerton Amtrak Stationbus bus
    22h 34m
    $309–1,146

  6. Fly to Burbank Bob Hope Airport, train

    1. Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Burbank Bob Hope Airport (BUR)plane plane SCL - BUR
    2. Take the train from Los Angeles to Santa Anatrain train
    22h 1m
    $336–1,232

  7. Fly to Ontario International Airport, train

    1. Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Ontario International Airport (ONT)plane plane SCL - ONT
    2. Take the train from San Bernardino Depot to Santa Anatrain train
    20h 19m
    $313–1,119

Comodoro Arturo Merino Benítez International Airport (SCL) to John Wayne Airport Orange County (SNA) flights

Calendar20Weekly Planes
Duration16h 31mAverage Duration
Ticket$354Cheapest Price
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Comparing Your Travel Options

Map of how to get from Santiago to Santa Ana.ExpandLaunch map view
  • Distance: 5,564.8 mi
  • Duration: 16h 35m

What companies run services between Santiago, Chile and Santa Ana, CA, USA?

American Airlines, United Airlines, and Delta fly from Comodoro Arturo Merino Benítez International Airport (SCL) to John Wayne Airport Orange County (SNA) 3 times a day.

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