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How to get fromSantiago to Santa Cruzby plane, train, bus, or car

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There are 6 ways to get from Santiago to Santa Cruz by plane, train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Puerto Natales

    best
    1. Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Puerto Natales (PNT)plane plane SCL - PNT
    5h 8m
    $118,129–380,429

  2. Train, bus

    1. Take the train from Estacion Central Alameda to Chillántrain train
    2. Take the bus from Terminal María Teresa to Terminal De Buses Osornobus bus
    3. Take the bus from Osorno to Villa La Angosturabus bus
    4. Take the bus from Villa La Angostura to Barilochebus bus
    5. Take the bus from Terminal de Omnibus Bariloche to Terminal de Ómnibus de Río Gallegosbus bus
    43h 10m
    $200,847–472,756

  3. Drive 2,705.7 km

    1. Drive from Santiago to Río Gallegoscar car 2,705.7 km
    31h 48m
    $500,532–722,990

  4. Fly to Piloto Civil Norberto Fernández International Airport

    1. Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Piloto Civil Norberto Fernández International Airport (RGL)plane plane SCL - RGL
    7h 58m
    $244,429–867,429

  5. Bus via Bariloche

    1. Take the bus from Terminal Sur to Barilochebus bus Bariloche / ...
    2. Take the bus from Terminal de Omnibus Bariloche to Terminal de Ómnibus de Río Gallegosbus bus Bariloche
    45h 58m
    $232,159–449,420

  6. Bus

    1. Take the bus from Terminal Sur de Santiago to Potrerillosbus bus
    2. Take the bus from Potrerillos to Terminal Mendozabus bus
    3. Take the bus from Terminal Mendoza to Terminal Río Cuartobus bus
    4. Take the bus from Terminal Río Cuarto to Terminal de Ómnibus de Río Gallegosbus bus
    2d 3h
    $360,445–571,645

Comodoro Arturo Merino Benítez International Airport (SCL) to Puerto Natales (PNT) flights

Calendar12Weekly Planes
Duration3h 59mAverage Duration
Ticket$114,146Cheapest Price
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Questions & Answers

Map of how to get from Santiago to Santa Cruz.ExpandLaunch map view
  • Distance: 2,077.5 km
  • Duration: 5h 8m

What companies run services between Santiago, Chile and Santa Cruz, Argentina?

Sky Airline and LATAM Chile fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Puerto Natales (PNT) twice daily. Alternatively, you can take a subway from Pajaritos Dirección Los Domínicos to Río Gallegos via Universidad de Santiago Dirección Los Domínicos, Terminal Sur, Terminal de Omnibus Bariloche, and Terminal de Ómnibus de Río Gallegos in around 45h 58m.

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