There are 5 ways to get from Santiago to Santa Cruz by bus (Flixbus), train, bus, car, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Terminal Sur de Santiago to Hospitalbus Santiago
2h 41m$4–35Train, bus
- Take the train from Estacion Central Alameda to San Fernandotrain Santiago / ...
- Take the bus from San Fernando to Santa Cruzbus FlixBus CL027 / ...
3h 10m$11–35Drive 179.8 km
- Drive from Santiago to Santa Cruzcar 179.8 km
2h 3m$23–32Taxi
- Take the taxi from Santiago to Santa Cruztaxi 179.8 km
2h 3m$140–170Bus via Marchihue
- Take the bus from Terminal Sur de Santiago to Marchihuebus Santiago / ...
4h 21m$6–20
Santiago to Santa Cruz by bus
Questions & Answers
The cheapest way to get from Santiago to Santa Cruz is to bus which costs $4 - $35 and takes 2h 41m.
The fastest way to get from Santiago to Santa Cruz is to drive which takes 2h 3m and costs $22 - $35.
Yes, there is a direct bus departing from Terminal Sur de Santiago and arriving at Hospital. Services depart hourly, and operate every day. The journey takes approximately 2h 41m.
The distance between Santiago and Santa Cruz is 178 km. The road distance is 179.8 km.
The best way to get from Santiago to Santa Cruz without a car is to bus which takes 2h 41m and costs $4 - $35.
The bus from Terminal Sur de Santiago to Hospital takes 2h 41m including transfers and departs hourly.
Santiago to Santa Cruz bus services, operated by Andimar, depart from Terminal Sur de Santiago station.
Santiago to Santa Cruz bus services, operated by Andimar, arrive at Hospital station.
Yes, the driving distance between Santiago to Santa Cruz is 180 km. It takes approximately 2h 3m to drive from Santiago to Santa Cruz.
Book your Santiago to Santa Cruz bus tickets online with Omio and FlixBus.
What companies run services between Santiago, Chile and Santa Cruz, O'Higgins, Chile?
Andimar operates a bus from Terminal Sur de Santiago to Hospital hourly. Tickets cost $4–11 and the journey takes 2h 41m. Five other operators also service this route.
- Phone
- +56 22 585 5000
- [email protected]
- Website
- efe.cl
Train from Estacion Central Alameda to San Fernando
- Phone
- +56 22 683 8528
- [email protected]
- Website
- Andimar
Bus from Terminal Sur de Santiago to Hospital
- Ave. Duration
- 2h 41m
- Frequency
- Hourly
- Estimated price
- $4–11
- Schedules at
- Andimar
- Semi Cama
- $4–9
- Cama
- $5–11
- Website
- Flixbus Chile
Bus from Terminal Sur de Santiago to Hospital
- Ave. Duration
- 2h 40m
- Frequency
- Hourly
- Estimated price
- $17–29
- Schedules at
- Flixbus Chile
Bus from San Fernando to Santa Cruz
- Ave. Duration
- 50 min
- Frequency
- Hourly
- Estimated price
- $4–8
- Schedules at
- Flixbus Chile
- [email protected]
- Website
- Expreso Santa Cruz
Bus from Terminal Sur de Santiago to Hospital
- Ave. Duration
- 3h
- Frequency
- Every 30 minutes
- Estimated price
- $8
- Schedules at
- Expreso Santa Cruz
Bus from Terminal Sur de Santiago to Hospital
- Ave. Duration
- 3h 20m
- Frequency
- Every 30 minutes
- Estimated price
- $4–11
- Schedules at
- TranSantin
- Road
- $4–11
Bus from Terminal Sur de Santiago to Marchihue
- Ave. Duration
- 3h 30m
- Frequency
- Every 30 minutes
- Estimated price
- $4–11
- Schedules at
- TranSantin
- Road
- $4–11
- Phone
- +56 600 600 0018
- [email protected]
- Website
- pullmanbus.cl
Bus from Terminal Sur de Santiago to Hospital
- Ave. Duration
- 3h
- Frequency
- 4 times a day
- Estimated price
- $12–35
- Schedules at
- pullmanbus.cl
- Book at
- pullmanbus.cl
- Salón Cama
- $13–35
Bus from San Fernando to Santa Cruz
- Ave. Duration
- 1h
- Frequency
- 4 times a day
- Estimated price
- $9–30
- Schedules at
- pullmanbus.cl
- Book at
- pullmanbus.cl
- Salón Cama
- $9–30
- Phone
- +56 2 2666 5505
- [email protected]
- Website
- Buses Jetsur
Bus from Terminal Sur de Santiago to Hospital
- Ave. Duration
- 3h 13m
- Frequency
- 4 times a day
- Estimated price
- $10–13
- Website
- Buses Jetsur
- Ave. Duration
- 2h 3m
- Estimated price
- $140–170
Mobicab
- Phone
- +56 2 2954 6013
- Website
- transportesantiago.movicab.cl
Radio Taxi Las Golondrinas
- Phone
- +56 2 2789 6308
- Website
- radiotaxilasgolondrinas.cl
Radio Taxi Lautaro
- Phone
- +56 2 2835 6600
- Website
- radiotaxilautaro.cl
Radio Taxi Metropolitano
- Phone
- +56 2 2506 6595
- Website
- radiotaximetropolitano.cl
Taxi Oficial
- Phone
- +56 2 2601 9880
- Website
- taxioficial.cl
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