There are 3 ways to get from Santiago to Santiago de Cuba by plane, shuttle, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Antonio Maceo International Airport
best- Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Antonio Maceo International Airport (SCU)plane SCL - SCU
14h 27m$295–1,105Fly to Ignacio Agramonte International Airport, bus
cheapest- Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Ignacio Agramonte International Airport (CMW)plane SCL - CMW
- Take the bus from Camagüey to Santiago de Cubabus
21h 14m$246–909Fly to Frank País International Airport, shuttle
- Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Frank País International Airport (HOG)plane SCL - HOG
- Take a shuttle bus from Hotel Pernik Holguin to Melia Santiago de Cuba
19h 50m$285–1,040
Comodoro Arturo Merino Benítez International Airport (SCL) to Antonio Maceo International Airport (SCU) flights
Questions & Answers
The cheapest way to get from Santiago to Santiago de Cuba is to fly and bus which costs $240 - $950 and takes 21h 14m.
The fastest way to get from Santiago to Santiago de Cuba is to fly which takes 14h 27m and costs $290 - $1,200.
The distance between Santiago and Santiago de Cuba is 5978 km.
It takes approximately 14h 27m to get from Santiago to Santiago de Cuba, including transfers.
What companies run services between Santiago, Chile and Santiago de Cuba?
American Airlines and LATAM Chile fly from Comodoro Arturo Merino Benítez International Airport (SCL) to Antonio Maceo International Airport (SCU) once daily.
- Website
- aa.com
Flights from Comodoro Arturo Merino Benítez International Airport to Antonio Maceo International Airport via Miami
- Ave. Duration
- 12h 20m
- When
- Wednesday to Sunday
- Estimated price
- $290–1,200
Flights from Comodoro Arturo Merino Benítez International Airport to Frank País International Airport via Miami
- Ave. Duration
- 15h 10m
- When
- Every day
- Estimated price
- $250–1,100
Flights from Comodoro Arturo Merino Benítez International Airport to Ignacio Agramonte International Airport via Miami
- Ave. Duration
- 14h 50m
- When
- Every day
- Estimated price
- $240–1,000
- Phone
- +(537) 206 9590
- [email protected]
- Website
- ecured.cu
Shuttle from Hotel Pernik Holguin to Melia Santiago de Cuba
- Ave. Duration
- 1h 9m
- Frequency
- Twice daily
- Estimated price
- $28–80
- Schedules at
- viajescubanacan.cu
- Phone
- +53 7873 7373
- [email protected]
- Website
- Ómnibus Nacionales
Bus from Camagüey to Santiago de Cuba
- Ave. Duration
- 4h
- Frequency
- 4 times a week
- Estimated price
- $2–5
- Schedules at
- Ómnibus Nacionales
Want to know more about travelling around the world?
Rome2Rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including 4 stunningly beautiful Philippines islands you need to visit, Why you should take the train in the US, and How do I get from Sydney to Melbourne - to help you get the most out of your next trip.